3-[3-[[2-(3,4-DIMETHOXYPHENYL)ETHYL]METHYLAMINO]PROPYL]-1,3,4,5-TETRAHYDRO-7,8-DIMETHOXY-2H-3-BENZAZEPIN-2-ONE HYDROCHLORIDE
![3-[3-[[2-(3,4-DIMETHOXYPHENYL)ETHYL]METHYLAMINO]PROPYL]-1,3,4,5-TETRAHYDRO-7,8-DIMETHOXY-2H-3-BENZAZEPIN-2-ONE HYDROCHLORIDE price.](/CAS/GIF/91940-87-3.gif)
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- $43 - $2000
- Product name: 3-[3-[[2-(3,4-DIMETHOXYPHENYL)ETHYL]METHYLAMINO]PROPYL]-1,3,4,5-TETRAHYDRO-7,8-DIMETHOXY-2H-3-BENZAZEPIN-2-ONE HYDROCHLORIDE
- CAS: 91940-87-3
- MF: C26H37ClN2O5
- MW: 493.04
- EINECS:
- MDL Number:MFCD06798356
- Synonyms:UL-FS49;ZATEBRADINE HYDROCHLORIDE;UL-FS49, 3-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one hydrochloride;3-[3-[[2-(3,4-DIMETHOXYPHENYL)ETHYL]METHYLAMINO]PROPYL]-1,3,4,5-TETRAHYDRO-7,8-DIMETHOXY-2H-3-BENZAZEPIN-2-ONE HYDROCHLORIDE;2H-3-Benzazepin-2-one, 3-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-, monohydrochloride;Zatebradine HCl;ULFS 49CL;Zatebradine dihydrochloride
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Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 5mg
- 50
- 1mg
- 10mg
- 25mg
- 50mg
- 1g
- ManufacturerAK Scientific
- Product number4166AH
- Product descriptionZatebradine hydrochloride
- Packaging5mg
- Price$214
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6974
- Product descriptionZatebradine hydrochloride
- Packaging5mg
- Price$156
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6974
- Product descriptionZatebradine hydrochloride
- Packaging10mg
- Price$268
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6974
- Product descriptionZatebradine hydrochloride
- Packaging50mg
- Price$1087
- Updated2021-12-16
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- ManufacturerCayman Chemical
- Product number18608
- Product descriptionZatebradine (hydrochloride) ≥95%
- Packaging5mg
- Price$106
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18608
- Product descriptionZatebradine (hydrochloride) ≥95%
- Packaging10mg
- Price$178
- Updated2024-03-01
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- ManufacturerCayman Chemical
- Product number18608
- Product descriptionZatebradine (hydrochloride) ≥95%
- Packaging25mg
- Price$388
- Updated2024-03-01
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- ManufacturerCayman Chemical
- Product number18608
- Product descriptionZatebradine (hydrochloride) ≥95%
- Packaging50mg
- Price$723
- Updated2024-03-01
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- ManufacturerChemScene
- Product numberCS-3619
- Product descriptionZatebradine hydrochloride 99.30%
- Packaging5mg
- Price$85
- Updated2021-12-16
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- ManufacturerChemScene
- Product numberCS-3619
- Product descriptionZatebradine hydrochloride 99.30%
- Packaging10mg
- Price$135
- Updated2021-12-16
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- ManufacturerChemScene
- Product numberCS-3619
- Product descriptionZatebradine hydrochloride 99.30%
- Packaging50mg
- Price$588
- Updated2021-12-16
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- ManufacturerCrysdot
- Product numberCD31000255
- Product descriptionZatebradine hydrochloride 98+%
- Packaging10mg
- Price$90
- Updated2021-12-16
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- ManufacturerCrysdot
- Product numberCD31000255
- Product descriptionZatebradine hydrochloride 98+%
- Packaging50mg
- Price$343
- Updated2021-12-16
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- ManufacturerCSNpharm
- Product numberCSN18579
- Product descriptionZatebradineHCl
- Packaging1mg
- Price$43
- Updated2021-12-16
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- ManufacturerCSNpharm
- Product numberCSN18579
- Product descriptionZatebradineHCl
- Packaging10mg
- Price$115
- Updated2021-12-16
- Buy
- ManufacturerCSNpharm
- Product numberCSN18579
- Product descriptionZatebradineHCl
- Packaging50mg
- Price$500
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 4166AH | Zatebradine hydrochloride | 5mg | $214 | 2021-12-16 | Buy |
| ApexBio Technology | B6974 | Zatebradine hydrochloride | 5mg | $156 | 2021-12-16 | Buy |
| ApexBio Technology | B6974 | Zatebradine hydrochloride | 10mg | $268 | 2021-12-16 | Buy |
| ApexBio Technology | B6974 | Zatebradine hydrochloride | 50mg | $1087 | 2021-12-16 | Buy |
| Cayman Chemical | 18608 | Zatebradine (hydrochloride) ≥95% | 5mg | $106 | 2024-03-01 | Buy |
| Cayman Chemical | 18608 | Zatebradine (hydrochloride) ≥95% | 10mg | $178 | 2024-03-01 | Buy |
| Cayman Chemical | 18608 | Zatebradine (hydrochloride) ≥95% | 25mg | $388 | 2024-03-01 | Buy |
| Cayman Chemical | 18608 | Zatebradine (hydrochloride) ≥95% | 50mg | $723 | 2024-03-01 | Buy |
| ChemScene | CS-3619 | Zatebradine hydrochloride 99.30% | 5mg | $85 | 2021-12-16 | Buy |
| ChemScene | CS-3619 | Zatebradine hydrochloride 99.30% | 10mg | $135 | 2021-12-16 | Buy |
| ChemScene | CS-3619 | Zatebradine hydrochloride 99.30% | 50mg | $588 | 2021-12-16 | Buy |
| Crysdot | CD31000255 | Zatebradine hydrochloride 98+% | 10mg | $90 | 2021-12-16 | Buy |
| Crysdot | CD31000255 | Zatebradine hydrochloride 98+% | 50mg | $343 | 2021-12-16 | Buy |
| CSNpharm | CSN18579 | ZatebradineHCl | 1mg | $43 | 2021-12-16 | Buy |
| CSNpharm | CSN18579 | ZatebradineHCl | 10mg | $115 | 2021-12-16 | Buy |
| CSNpharm | CSN18579 | ZatebradineHCl | 50mg | $500 | 2021-12-16 | Buy |
Properties
Melting point :188° and mp 168°
storage temp. :2-8°C
solubility :H2O: ~14 mg/mL
form :solid
color :white
Water Solubility :Soluble in water (100mM)
storage temp. :2-8°C
solubility :H2O: ~14 mg/mL
form :solid
color :white
Water Solubility :Soluble in water (100mM)
Safety Information
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Description
Zatebradine is a bradycardic compound that blocks hyperpolarization-activated inward current (If) through cyclic nucleotide-gated cation (HCN) channels in sinoatrial node cells (IC50s = 1.83, 2.21, 1.9, and 1.88 μM, respectively for HCN1-4 in vitro). Additionally, it can block voltage-gated outward K+ (IK) currents and related neuronal hyperpolarization-activated inward current (Ih) channels, but exhibits little or no activity for L-type Ca2+ (ICa) currents. When assessed through telemetric ECG recording in mice, zatebradine reduced heart rate from 600 to 200 beats per minute with an ED50 value of 1.8 mg/kg and induced increasing arrhythmia at concentrations >10 mg/kg.More related product prices
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