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ChemicalBook >> CAS DataBase List >> 4-Chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine

4-Chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine

4-Chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine price.
  • $8 - $790
  • Product name: 4-Chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine
  • CAS: 941685-26-3
  • MF: C12H18ClN3OSi
  • MW: 283.83
  • EINECS:1592732-453-0
  • MDL Number:MFCD11857752
  • Synonyms:7H-Pyrrolo[2,3-d]pyriMidine, 4-chloro-7-[[2-(triMethylsilyl)ethoxy]Methyl]-;2-[(4-CHLOROPYRROLO[2,3-D]PYRIMIDIN-7-YL)METHOXY]ETHYL-TRIMETHYLSILANE;4-Chloro-7-((2-(trimethylsilyl)ethoxy)methyl-7H-pyrrolo[2,3-...;4-chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrolo[2,3-D]pyrimidine;Baricitinib Impurity 72;Ruxolitinib SEM Chloro pyrimidine;Baritinib impurity 9;4-Chloro-7-[[2-(trimethylsilanyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine
Price30 Properties Safety Information Description
30 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • American Custom Chemicals Corporation
  • Arctom
  • Chemenu
  • Crysdot
  • SynQuest Laboratories
  • Synthonix
  • TRC
Package
  • 250mg
  • 1g
  • 5g
  • 10g
  • 25g
  • 50g
  • 100G
  • Manufactureraablocks
  • Product numberAA00GSTU
  • Product description4-Chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine 98%
  • Packaging1g
  • Price$8
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GSTU
  • Product description4-Chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine ≥95%
  • Packaging5g
  • Price$25
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GSTU
  • Product description4-Chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine 95%
  • Packaging25g
  • Price$60
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GSTU
  • Product description4-Chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine ≥95%
  • Packaging10g
  • Price$40
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GSTU
  • Product description4-Chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine 95%
  • Packaging50g
  • Price$111
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberL13497
  • Product description4-Chloro-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine 97%
  • Packaging100G
  • Price$330
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberL13497
  • Product description4-Chloro-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine 97%
  • Packaging25G
  • Price$105
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberL13497
  • Product description4-Chloro-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine 97%
  • Packaging5G
  • Price$35
  • Updated2026-05-27
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberORS0004029
  • Product description4-CHLORO-7-((2-(TRIMETHYLSILYL)ETHOXY)METHYL)-7H-PYRROLO[2,3-D]PYRIMIDINE 95.00%
  • Packaging1G
  • Price$191.1
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberSY047225
  • Product description4-Chloro-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine ≥95%
  • Packaging100g
  • Price$209
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberSY047225
  • Product description4-Chloro-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine ≥95%
  • Packaging25g
  • Price$64
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberSY047225
  • Product description4-Chloro-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine ≥95%
  • Packaging10g
  • Price$34
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberSY047225
  • Product description4-Chloro-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine ≥95%
  • Packaging1g
  • Price$13
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberSY047225
  • Product description4-Chloro-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine ≥95%
  • Packaging5g
  • Price$22
  • Updated2026-05-26
  • Buy
  • ManufacturerChemenu
  • Product numberCM103625
  • Product description4-chloro-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine 95%+
  • Packaging25g
  • Price$160
  • Updated2026-05-26
  • Buy
  • ManufacturerChemenu
  • Product numberCM103625
  • Product description4-chloro-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine 95%+
  • Packaging250mg
  • Price$59
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00GSTU 4-Chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine 98% 1g $8 2026-05-28 Buy
aablocks AA00GSTU 4-Chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine ≥95% 5g $25 2026-05-28 Buy
aablocks AA00GSTU 4-Chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine 95% 25g $60 2026-05-28 Buy
aablocks AA00GSTU 4-Chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine ≥95% 10g $40 2026-05-28 Buy
aablocks AA00GSTU 4-Chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine 95% 50g $111 2026-05-28 Buy
ACHEMBLOCK L13497 4-Chloro-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine 97% 100G $330 2026-05-27 Buy
ACHEMBLOCK L13497 4-Chloro-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine 97% 25G $105 2026-05-27 Buy
ACHEMBLOCK L13497 4-Chloro-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine 97% 5G $35 2026-05-27 Buy
American Custom Chemicals Corporation ORS0004029 4-CHLORO-7-((2-(TRIMETHYLSILYL)ETHOXY)METHYL)-7H-PYRROLO[2,3-D]PYRIMIDINE 95.00% 1G $191.1 2021-12-16 Buy
Arctom SY047225 4-Chloro-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine ≥95% 100g $209 2026-05-26 Buy
Arctom SY047225 4-Chloro-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine ≥95% 25g $64 2026-05-26 Buy
Arctom SY047225 4-Chloro-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine ≥95% 10g $34 2026-05-26 Buy
Arctom SY047225 4-Chloro-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine ≥95% 1g $13 2026-05-26 Buy
Arctom SY047225 4-Chloro-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine ≥95% 5g $22 2026-05-26 Buy
Chemenu CM103625 4-chloro-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine 95%+ 25g $160 2026-05-26 Buy
Chemenu CM103625 4-chloro-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine 95%+ 250mg $59 2021-12-16 Buy
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Properties

Boiling point :368.3±37.0 °C(Predicted)
Density :1.17±0.1 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
pka :3.00±0.30(Predicted)
Appearance :White to off-white Solid
InChI :InChI=1S/C12H18ClN3OSi/c1-18(2,3)7-6-17-9-16-5-4-10-11(13)14-8-15-12(10)16/h4-5,8H,6-7,9H2,1-3H3
InChIKey :YWBDBLXIRAQZIH-UHFFFAOYSA-N
SMILES :C1=NC(Cl)=C2C=CN(COCC[Si](C)(C)C)C2=N1

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

4-Chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine is used in the design and preparation of ruxolitinib-vorinostat conjugate derivatives which have dual inhibitory activity against Janus kinase (JAK) and histone deacetylase (HDAC).

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Suppliers and manufacturers

Bayee Biotech (Anqing) Co., Ltd. Jiangsu Vcare PharmaTech Co., Ltd. Shandong Meiao Huawei Technology Co., LTD Taizhou Yuxin Biotechnology Co., Ltd., Wuhan Chemwish Technology Co., Ltd Adamas Reagent, Ltd. Hangzhou Sage Chemical Co., Ltd. Nanjing Norris-Pharm Technology Co., Ltd Shanghai Jian Chao Chemical Technology Co., Ltd. SHANGHAI YINGRUI CHEMICAL TECHNOLOGY CO.,LTD.