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ChemicalBook >> CAS DataBase List >> N-benzyl-4-chloro-N-cyclohexylbenzaMide

N-benzyl-4-chloro-N-cyclohexylbenzaMide

N-benzyl-4-chloro-N-cyclohexylbenzaMide price.
  • $13 - $1200
  • Product name: N-benzyl-4-chloro-N-cyclohexylbenzaMide
  • CAS: 945714-67-0
  • MF: C20H22ClNO
  • MW: 327.85
  • EINECS:
  • MDL Number:MFCD22378757
  • Synonyms:N-benzyl-4-chloro-N-cyclohexylbenzaMide;FPS-ZM1;4-Chloro-N-cyclohexyl-N-(phenylmethyl)benzamide;CS-2304;Benzamide, 4-chloro-N-cyclohexyl-N-(phenylmethyl)-;FPS-ZM1, RAGE receptor antagonist;FPS-ZM1, 10 mM in DMSO
29 prices
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Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
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  • 10mg
  • 25mg
  • 50mg
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  • 200mg
  • 250mg
  • 1g
  • 25 mg
  • ManufacturerAK Scientific
  • Product number1294DC
  • Product descriptionFps-ZM1
  • Packaging25mg
  • Price$284
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA171795
  • Product descriptionFPS-ZM1 98+%
  • Packaging1mg
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA171795
  • Product descriptionFPS-ZM1 98+%
  • Packaging5mg
  • Price$22
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA171795
  • Product descriptionFPS-ZM1 98+%
  • Packaging10mg
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA171795
  • Product descriptionFPS-ZM1 98+%
  • Packaging50mg
  • Price$48
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA171795
  • Product descriptionFPS-ZM1 98+%
  • Packaging100mg
  • Price$64
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA171795
  • Product descriptionFPS-ZM1 98+%
  • Packaging250mg
  • Price$132
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA171795
  • Product descriptionFPS-ZM1 98+%
  • Packaging1g
  • Price$334
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBRS0009229
  • Product descriptionN-BENZYL-4-CHLORO-N-CYCLOHEXYLBENZAMIDE 95.00%
  • Packaging5MG
  • Price$504.35
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3723
  • Product descriptionFPS-ZM1
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545944
  • Product descriptionFPS-ZM1 >98%
  • Packaging5mg
  • Price$127.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545944
  • Product descriptionFPS-ZM1 >98%
  • Packaging25mg
  • Price$299.2
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11909
  • Product descriptionFPS-ZM1 ≥98%
  • Packaging5mg
  • Price$30
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11909
  • Product descriptionFPS-ZM1 ≥98%
  • Packaging10mg
  • Price$54
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11909
  • Product descriptionFPS-ZM1 ≥98%
  • Packaging25mg
  • Price$105
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM255935
  • Product descriptionN-Benzyl-4-chloro-N-cyclohexylbenzamide 98%
  • Packaging100mg
  • Price$404
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1294DC Fps-ZM1 25mg $284 2021-12-16 Buy
Ambeed A171795 FPS-ZM1 98+% 1mg $13 2021-12-16 Buy
Ambeed A171795 FPS-ZM1 98+% 5mg $22 2021-12-16 Buy
Ambeed A171795 FPS-ZM1 98+% 10mg $28 2021-12-16 Buy
Ambeed A171795 FPS-ZM1 98+% 50mg $48 2021-12-16 Buy
Ambeed A171795 FPS-ZM1 98+% 100mg $64 2021-12-16 Buy
Ambeed A171795 FPS-ZM1 98+% 250mg $132 2021-12-16 Buy
Ambeed A171795 FPS-ZM1 98+% 1g $334 2021-12-16 Buy
American Custom Chemicals Corporation BRS0009229 N-BENZYL-4-CHLORO-N-CYCLOHEXYLBENZAMIDE 95.00% 5MG $504.35 2021-12-16 Buy
ApexBio Technology C3723 FPS-ZM1 5mg $50 2021-12-16 Buy
Biorbyt Ltd orb545944 FPS-ZM1 >98% 5mg $127.5 2021-12-16 Buy
Biorbyt Ltd orb545944 FPS-ZM1 >98% 25mg $299.2 2021-12-16 Buy
Cayman Chemical 11909 FPS-ZM1 ≥98% 5mg $30 2024-03-01 Buy
Cayman Chemical 11909 FPS-ZM1 ≥98% 10mg $54 2024-03-01 Buy
Cayman Chemical 11909 FPS-ZM1 ≥98% 25mg $105 2024-03-01 Buy
Chemenu CM255935 N-Benzyl-4-chloro-N-cyclohexylbenzamide 98% 100mg $404 2021-12-16 Buy

Properties

Boiling point :497.6±38.0 °C(Predicted)
Density :1.18±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 20 mg/ml)
form :solid
pka :-1.54±0.20(Predicted)
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

FPS-ZM1 (945714-67-0) is a high-affinity RAGE (Receptor for Advanced Glycation End products) receptor antagonist (IC50?= 0.6 μM). It lowers levels of Aβ via binding to the V domain of RAGE and can block multiple mechanisms of Aβ40- and Aβ42-induced cellular stress in RAGE-expressing brain endothelium, neurons and microglia?in vitro?and?in vivo.1,2? Can cross the BBB.? In a rat model of intracerebral hemorrhage, FPS-ZM1 was able to attenuate blood-brain barrier and white matter fiber damage.3?FPS-ZM1 antagonism of RAGE was able to ameliorate inflammatory damage after acute intracerebral hemorrhage via downstream blockade of high mobility box-1(HMGB1) signaling.4? FPS-ZM1 has also been shown to impair breast cancer cell invasion and metastasis.5