1-[4-(1,2,3,4-TETRAHYDROXYBUTYL)-1H-IMIDAZOL-2-YL]ETHANONE
![1-[4-(1,2,3,4-TETRAHYDROXYBUTYL)-1H-IMIDAZOL-2-YL]ETHANONE price.](/CAS/GIF/94944-70-4.gif)
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- $64 - $6143
- Product name: 1-[4-(1,2,3,4-TETRAHYDROXYBUTYL)-1H-IMIDAZOL-2-YL]ETHANONE
- CAS: 94944-70-4
- MF: C9H14N2O5
- MW: 230.22
- EINECS:
- MDL Number:MFCD03844698
- Synonyms:1-[4-(1,2,3,4-TETRAHYDROXYBUTYL)-1H-IMIDAZOL-2-YL]ETHANONE;2-acetyl-4(5)-tetrahydroxybutylimidazole;2-ACETYL-4(5)-(1,2,3,4-TETRAHYDROXYBUTYL)-IMIDAZOLE (THI);2-Athbi;Ethanone, 1-(4-(1,2,3,4-tetrahydroxybutyl)-1H-imidazol-2-yl)-, (1R-(1R*,2S*,3R*))-;Ethanone, 1-[5-[(1R,2S,3R)-1,2,3,4-tetrahydroxybutyl]-1H-iMidazol-2-yl]-;Ethanone, 1-[4-(1,2,3,4-tetrahydroxybutyl)-1H-iMidazol-2-yl]-, [1R-(1R*,2S*,3R*)]- (9CI);2-Acetyl-4-(1,2,3,4-tetrahydroxybutyl)iMidazole, 97%
50 prices
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Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Apolloscientific
- AvaChem
- Biosynth
- Cayman Chemical
- ChemScene
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Thermo Scientific Chemicals
- TRC
- Usbiological
Package
- 500μg
- 1mg
- 5mg
- 10.00mg
- 10mg
- 25MG
- 50mg
- 50.00mg
- 100mg
- 250mg
- 500mg
- 500.00mg
- 1000mg
- Manufactureraablocks
- Product numberAA005TZD
- Product description1-(5-(1,1,2,2-Tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone ≥95%
- Packaging1mg
- Price$131
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005TZD
- Product description1-(5-(1,1,2,2-Tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone ≥95%
- Packaging10mg
- Price$954
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005TZD
- Product description1-(5-(1,1,2,2-Tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone ≥95%
- Packaging5mg
- Price$547
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227007
- Product description2-ATHBI 95.00%
- Packaging5MG
- Price$135
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227007
- Product description2-ATHBI 95.00%
- Packaging25MG
- Price$405
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number4194AF
- Product description1-[4-(1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl]ethanone
- Packaging25mg
- Price$164
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number4194AF
- Product description1-[4-(1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl]ethanone
- Packaging50mg
- Price$252
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number4194AF
- Product description1-[4-(1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl]ethanone
- Packaging500mg
- Price$1602
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBICL2051
- Product description2-Acetyl-4-tetrahydroxybutyl imidazole
- Packaging50mg
- Price$395
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBICL2051
- Product description2-Acetyl-4-tetrahydroxybutyl imidazole
- Packaging25mg
- Price$228
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBICL2051
- Product description2-Acetyl-4-tetrahydroxybutyl imidazole
- Packaging100mg
- Price$687
- Updated2026-06-04
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- ManufacturerAvaChem
- Product number6856
- Product descriptionTHI 98%
- Packaging25mg
- Price$280
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number6856
- Product descriptionTHI 98%
- Packaging5mg
- Price$70
- Updated2026-05-22
- Buy
- ManufacturerBiosynth
- Product numberMA61366
- Product description2-Acetyl-4-tetrahydroxybutyl imidazole
- Packaging25mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberMA61366
- Product description2-Acetyl-4-tetrahydroxybutyl imidazole
- Packaging50mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberMA61366
- Product description2-Acetyl-4-tetrahydroxybutyl imidazole
- Packaging100mg
- Price$290
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA005TZD | 1-(5-(1,1,2,2-Tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone ≥95% | 1mg | $131 | 2026-05-28 | Buy |
| aablocks | AA005TZD | 1-(5-(1,1,2,2-Tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone ≥95% | 10mg | $954 | 2026-05-28 | Buy |
| aablocks | AA005TZD | 1-(5-(1,1,2,2-Tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone ≥95% | 5mg | $547 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y227007 | 2-ATHBI 95.00% | 5MG | $135 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y227007 | 2-ATHBI 95.00% | 25MG | $405 | 2026-05-27 | Buy |
| AK Scientific | 4194AF | 1-[4-(1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl]ethanone | 25mg | $164 | 2021-12-16 | Buy |
| AK Scientific | 4194AF | 1-[4-(1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl]ethanone | 50mg | $252 | 2021-12-16 | Buy |
| AK Scientific | 4194AF | 1-[4-(1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl]ethanone | 500mg | $1602 | 2021-12-16 | Buy |
| Apolloscientific | BICL2051 | 2-Acetyl-4-tetrahydroxybutyl imidazole | 50mg | $395 | 2026-06-04 | Buy |
| Apolloscientific | BICL2051 | 2-Acetyl-4-tetrahydroxybutyl imidazole | 25mg | $228 | 2026-06-04 | Buy |
| Apolloscientific | BICL2051 | 2-Acetyl-4-tetrahydroxybutyl imidazole | 100mg | $687 | 2026-06-04 | Buy |
| AvaChem | 6856 | THI 98% | 25mg | $280 | 2026-05-22 | Buy |
| AvaChem | 6856 | THI 98% | 5mg | $70 | 2026-05-22 | Buy |
| Biosynth | MA61366 | 2-Acetyl-4-tetrahydroxybutyl imidazole | 25mg | $85 | 2021-12-16 | Buy |
| Biosynth | MA61366 | 2-Acetyl-4-tetrahydroxybutyl imidazole | 50mg | $150 | 2021-12-16 | Buy |
| Biosynth | MA61366 | 2-Acetyl-4-tetrahydroxybutyl imidazole | 100mg | $290 | 2021-12-16 | Buy |
Properties
Melting point :approximate 230℃ (dec.)
Boiling point :613.5±65.0 °C(Predicted)
Density :1.536±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble2mg/mL, clear (warmed)
form :Powder
pka :10.63±0.10(Predicted)
color :white to light brown
Water Solubility :Soluble in distilled water, DMSO (>5 mg/ml), clear (warmed), and PBS pH 7.2 (~0.15 mg/ml).
Stability :Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.
InChI :1S/C9H14N2O5/c1-4(13)9-10-2-5(11-9)7(15)8(16)6(14)3-12/h2,6-8,12,14-16H,3H2,1H3,(H,10,11)/t6-,7-,8-/m1/s1
InChIKey :CQSIXFHVGKMLGQ-BWZBUEFSSA-N
SMILES :CC(=O)c1nc(c[nH]1)[C@@H](O)[C@H](O)[C@H](O)CO
CAS DataBase Reference :94944-70-4
Boiling point :613.5±65.0 °C(Predicted)
Density :1.536±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble2mg/mL, clear (warmed)
form :Powder
pka :10.63±0.10(Predicted)
color :white to light brown
Water Solubility :Soluble in distilled water, DMSO (>5 mg/ml), clear (warmed), and PBS pH 7.2 (~0.15 mg/ml).
Stability :Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.
InChI :1S/C9H14N2O5/c1-4(13)9-10-2-5(11-9)7(15)8(16)6(14)3-12/h2,6-8,12,14-16H,3H2,1H3,(H,10,11)/t6-,7-,8-/m1/s1
InChIKey :CQSIXFHVGKMLGQ-BWZBUEFSSA-N
SMILES :CC(=O)c1nc(c[nH]1)[C@@H](O)[C@H](O)[C@H](O)CO
CAS DataBase Reference :94944-70-4
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Sphingosine-1-phosphate (S1P) lyase catalyzes the irreversible decomposition of S1P to hexadecanaldehyde and phosphoethanolamine. 2-Acetyl-5-tetrahydroxybutyl imidazole (THI) is an inhibitor of S1P lyase. Because S1P lyase is primarily expressed in lymphatic tissue, treatment of mice with THI (50 μg/ml in drinking water) increases lymphoid tissue S1P concentrations 100-fold, reducing lymphocyte egress from thymus and peripheral lymphoid organs. The resulting lymphopenia is reversible following cessation of THI treatment. Reducing S1P lyase activity results in therapeutic levels of immunosuppression without the non-lymphoid lesions that result from synthetic S1P receptor agonists.Related product price
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Suppliers and manufacturers
BOC Sciences
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J & K SCIENTIFIC LTD.
Alfa Aesar
Hangzhou Sage Chemical Co., Ltd.
Nanjing JinruiJiuAn Biotechnology Co., Ltd.
Guangzhou Isun Pharmaceutical Co., Ltd
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