1-[4-(1,2,3,4-TETRAHYDROXYBUTYL)-1H-IMIDAZOL-2-YL]ETHANONE
![1-[4-(1,2,3,4-TETRAHYDROXYBUTYL)-1H-IMIDAZOL-2-YL]ETHANONE price.](/CAS/GIF/94944-70-4.gif)
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- $64 - $6143
- Product name: 1-[4-(1,2,3,4-TETRAHYDROXYBUTYL)-1H-IMIDAZOL-2-YL]ETHANONE
- CAS: 94944-70-4
- MF: C9H14N2O5
- MW: 230.22
- EINECS:
- MDL Number:MFCD03844698
- Synonyms:1-[4-(1,2,3,4-TETRAHYDROXYBUTYL)-1H-IMIDAZOL-2-YL]ETHANONE;2-acetyl-4(5)-tetrahydroxybutylimidazole;2-ACETYL-4(5)-(1,2,3,4-TETRAHYDROXYBUTYL)-IMIDAZOLE (THI);2-Athbi;Ethanone, 1-(4-(1,2,3,4-tetrahydroxybutyl)-1H-imidazol-2-yl)-, (1R-(1R*,2S*,3R*))-;2-Acetyl-5-tetrahydroxybutyl Imidazole;Ethanone, 1-[5-[(1R,2S,3R)-1,2,3,4-tetrahydroxybutyl]-1H-iMidazol-2-yl]-;Ethanone, 1-[4-(1,2,3,4-tetrahydroxybutyl)-1H-iMidazol-2-yl]-, [1R-(1R*,2S*,3R*)]- (9CI)
20 prices
Selected condition：
Brand
- AK Scientific
- Biosynth Carbosynth
- Cayman Chemical
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 500μg
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 500mg
- ManufacturerAK Scientific
- Product number4194AF
- Product description1-[4-(1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl]ethanone
- Packaging25mg
- Price$164
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number4194AF
- Product description1-[4-(1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl]ethanone
- Packaging50mg
- Price$252
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number4194AF
- Product description1-[4-(1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl]ethanone
- Packaging500mg
- Price$1602
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberMA61366
- Product description2-Acetyl-4-tetrahydroxybutyl imidazole
- Packaging25mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberMA61366
- Product description2-Acetyl-4-tetrahydroxybutyl imidazole
- Packaging50mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberMA61366
- Product description2-Acetyl-4-tetrahydroxybutyl imidazole
- Packaging100mg
- Price$290
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberMA61366
- Product description2-Acetyl-4-tetrahydroxybutyl imidazole
- Packaging250mg
- Price$625
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberMA61366
- Product description2-Acetyl-4-tetrahydroxybutyl imidazole
- Packaging500mg
- Price$1150
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13222
- Product description2-Acetyl-5-tetrahydroxybutyl Imidazole ≥95%
- Packaging500μg
- Price$64
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13222
- Product description2-Acetyl-5-tetrahydroxybutyl Imidazole ≥95%
- Packaging1mg
- Price$119
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13222
- Product description2-Acetyl-5-tetrahydroxybutyl Imidazole ≥95%
- Packaging5mg
- Price$497
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13222
- Product description2-Acetyl-5-tetrahydroxybutyl Imidazole ≥95%
- Packaging10mg
- Price$867
- Updated2024-03-01
- Buy
- ManufacturerMatrix Scientific
- Product number089250
- Product description1-[4-(1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl]ethanone
- Packaging10mg
- Price$788
- Updated2021-12-16
- Buy
- ManufacturerMatrix Scientific
- Product number089250
- Product description1-[4-(1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl]ethanone
- Packaging50mg
- Price$3073
- Updated2021-12-16
- Buy
- ManufacturerMatrix Scientific
- Product number089250
- Product description1-[4-(1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl]ethanone
- Packaging500mg
- Price$6143
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number42759
- Product description(R,S,R)-2-Acetyl-4-(1,2,3,4-tetrahydroxybutyl)-imidazole
- Packaging100mg
- Price$650
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 4194AF | 1-[4-(1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl]ethanone | 25mg | $164 | 2021-12-16 | Buy |
| AK Scientific | 4194AF | 1-[4-(1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl]ethanone | 50mg | $252 | 2021-12-16 | Buy |
| AK Scientific | 4194AF | 1-[4-(1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl]ethanone | 500mg | $1602 | 2021-12-16 | Buy |
| Biosynth Carbosynth | MA61366 | 2-Acetyl-4-tetrahydroxybutyl imidazole | 25mg | $85 | 2021-12-16 | Buy |
| Biosynth Carbosynth | MA61366 | 2-Acetyl-4-tetrahydroxybutyl imidazole | 50mg | $150 | 2021-12-16 | Buy |
| Biosynth Carbosynth | MA61366 | 2-Acetyl-4-tetrahydroxybutyl imidazole | 100mg | $290 | 2021-12-16 | Buy |
| Biosynth Carbosynth | MA61366 | 2-Acetyl-4-tetrahydroxybutyl imidazole | 250mg | $625 | 2021-12-16 | Buy |
| Biosynth Carbosynth | MA61366 | 2-Acetyl-4-tetrahydroxybutyl imidazole | 500mg | $1150 | 2021-12-16 | Buy |
| Cayman Chemical | 13222 | 2-Acetyl-5-tetrahydroxybutyl Imidazole ≥95% | 500μg | $64 | 2024-03-01 | Buy |
| Cayman Chemical | 13222 | 2-Acetyl-5-tetrahydroxybutyl Imidazole ≥95% | 1mg | $119 | 2024-03-01 | Buy |
| Cayman Chemical | 13222 | 2-Acetyl-5-tetrahydroxybutyl Imidazole ≥95% | 5mg | $497 | 2024-03-01 | Buy |
| Cayman Chemical | 13222 | 2-Acetyl-5-tetrahydroxybutyl Imidazole ≥95% | 10mg | $867 | 2024-03-01 | Buy |
| Matrix Scientific | 089250 | 1-[4-(1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl]ethanone | 10mg | $788 | 2021-12-16 | Buy |
| Matrix Scientific | 089250 | 1-[4-(1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl]ethanone | 50mg | $3073 | 2021-12-16 | Buy |
| Matrix Scientific | 089250 | 1-[4-(1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl]ethanone | 500mg | $6143 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 42759 | (R,S,R)-2-Acetyl-4-(1,2,3,4-tetrahydroxybutyl)-imidazole | 100mg | $650 | 2021-12-16 | Buy |
Properties
Melting point :approximate 230℃ (dec.)
Boiling point :613.5±65.0 °C(Predicted)
Density :1.536±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble2mg/mL, clear (warmed)
form :Powder
pka :10.63±0.10(Predicted)
color :white to light brown
Water Solubility :Soluble in distilled water, DMSO (>5 mg/ml), clear (warmed), and PBS pH 7.2 (~0.15 mg/ml).
Stability :Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.
InChI :1S/C9H14N2O5/c1-4(13)9-10-2-5(11-9)7(15)8(16)6(14)3-12/h2,6-8,12,14-16H,3H2,1H3,(H,10,11)/t6-,7-,8-/m1/s1
InChIKey :CQSIXFHVGKMLGQ-BWZBUEFSSA-N
SMILES :CC(=O)c1nc(c[nH]1)[C@@H](O)[C@H](O)[C@H](O)CO
CAS DataBase Reference :94944-70-4
Boiling point :613.5±65.0 °C(Predicted)
Density :1.536±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble2mg/mL, clear (warmed)
form :Powder
pka :10.63±0.10(Predicted)
color :white to light brown
Water Solubility :Soluble in distilled water, DMSO (>5 mg/ml), clear (warmed), and PBS pH 7.2 (~0.15 mg/ml).
Stability :Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.
InChI :1S/C9H14N2O5/c1-4(13)9-10-2-5(11-9)7(15)8(16)6(14)3-12/h2,6-8,12,14-16H,3H2,1H3,(H,10,11)/t6-,7-,8-/m1/s1
InChIKey :CQSIXFHVGKMLGQ-BWZBUEFSSA-N
SMILES :CC(=O)c1nc(c[nH]1)[C@@H](O)[C@H](O)[C@H](O)CO
CAS DataBase Reference :94944-70-4
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Sphingosine-1-phosphate (S1P) lyase catalyzes the irreversible decomposition of S1P to hexadecanaldehyde and phosphoethanolamine. 2-Acetyl-5-tetrahydroxybutyl imidazole (THI) is an inhibitor of S1P lyase. Because S1P lyase is primarily expressed in lymphatic tissue, treatment of mice with THI (50 μg/ml in drinking water) increases lymphoid tissue S1P concentrations 100-fold, reducing lymphocyte egress from thymus and peripheral lymphoid organs. The resulting lymphopenia is reversible following cessation of THI treatment. Reducing S1P lyase activity results in therapeutic levels of immunosuppression without the non-lymphoid lesions that result from synthetic S1P receptor agonists.Related product price
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Suppliers and manufacturers
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