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ChemicalBook >> CAS DataBase List >> H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-HIS-ASP-OH

H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-HIS-ASP-OH

H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-HIS-ASP-OH price.
  • $55 - $1462
  • Product name: H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-HIS-ASP-OH
  • CAS: 99534-03-9
  • MF: C94H148N32O31
  • MW: 2222.38
  • EINECS:
  • MDL Number:MFCD00133989
  • Synonyms:H-TTYADFIASGRTGRRNAIHD;H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-HIS-ASP-OH;CAMP DEPENDENT PK INHIBITOR (5-24);CAMP-DEPENDENT PROTEIN KINASE INHIBITOR (5-24);CAMP-DEPENDENT PROTEIN KINASE INHIBITOR-ALPHA (5-24) (HUMAN, MOUSE, RABBIT, RAT);ip20 ;TTYADFIASGRTGRRNAIHD;THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-HIS-ASP
14 prices
Selected condition:
Brand
  • AK Scientific
  • Alfa Aesar
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 1
  • 500μg
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerAK Scientific
  • Product number2591CW
  • Product description(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-4-Amino-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-carboxypropanoyl]amino]-3-phenylpropanoyl]amino]-3-methylpentanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-oxobutanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]butanedioicacid
  • Packaging1mg
  • Price$226
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2591CW
  • Product description(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-4-Amino-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-carboxypropanoyl]amino]-3-phenylpropanoyl]amino]-3-methylpentanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-oxobutanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]butanedioicacid
  • Packaging5mg
  • Price$619
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ66438
  • Product descriptioncAMP Dependent Protein Kinase Inhibitor (PKI 5-24)
  • Packaging1mg
  • Price$160
  • Updated2023-06-20
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb364468
  • Product descriptioncAMP Dependent PK Inhibitor (5-24) > 95%
  • Packaging1mg
  • Price$462.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb364468
  • Product descriptioncAMP Dependent PK Inhibitor (5-24) > 95%
  • Packaging5mg
  • Price$979.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb364468
  • Product descriptioncAMP Dependent PK Inhibitor (5-24) > 95%
  • Packaging10mg
  • Price$1462
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15996
  • Product descriptionPKA Inhibitor (5-24) ≥95%
  • Packaging500μg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15996
  • Product descriptionPKA Inhibitor (5-24) ≥95%
  • Packaging1mg
  • Price$94
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15996
  • Product descriptionPKA Inhibitor (5-24) ≥95%
  • Packaging5mg
  • Price$385
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0021889
  • Product descriptionPKI(5-24) 98.95%
  • Packaging5mg
  • Price$290
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0021889
  • Product descriptionPKI(5-24) 98.95%
  • Packaging10mg
  • Price$490
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number116805
  • Product descriptionPKA Inhibitor 5-24 - CAS 99534-03-9 - Calbiochem
  • Packaging500μg
  • Price$245
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number6221
  • Product descriptionPKI(5-24)
  • Packaging1
  • Price$161
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberP571593
  • Product descriptionPKI(5-24),PKAInhibitor
  • Packaging500μg
  • Price$95
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2591CW (2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-4-Amino-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-carboxypropanoyl]amino]-3-phenylpropanoyl]amino]-3-methylpentanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-oxobutanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]butanedioicacid 1mg $226 2021-12-16 Buy
AK Scientific 2591CW (2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-4-Amino-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-carboxypropanoyl]amino]-3-phenylpropanoyl]amino]-3-methylpentanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-oxobutanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]butanedioicacid 5mg $619 2021-12-16 Buy
Alfa Aesar J66438 cAMP Dependent Protein Kinase Inhibitor (PKI 5-24) 1mg $160 2023-06-20 Buy
Biorbyt Ltd orb364468 cAMP Dependent PK Inhibitor (5-24) > 95% 1mg $462.4 2021-12-16 Buy
Biorbyt Ltd orb364468 cAMP Dependent PK Inhibitor (5-24) > 95% 5mg $979.2 2021-12-16 Buy
Biorbyt Ltd orb364468 cAMP Dependent PK Inhibitor (5-24) > 95% 10mg $1462 2021-12-16 Buy
Cayman Chemical 15996 PKA Inhibitor (5-24) ≥95% 500μg $55 2021-12-16 Buy
Cayman Chemical 15996 PKA Inhibitor (5-24) ≥95% 1mg $94 2021-12-16 Buy
Cayman Chemical 15996 PKA Inhibitor (5-24) ≥95% 5mg $385 2021-12-16 Buy
ChemScene CS-0021889 PKI(5-24) 98.95% 5mg $290 2021-12-16 Buy
ChemScene CS-0021889 PKI(5-24) 98.95% 10mg $490 2021-12-16 Buy
Sigma-Aldrich 116805 PKA Inhibitor 5-24 - CAS 99534-03-9 - Calbiochem 500μg $245 2024-03-01 Buy
Tocris 6221 PKI(5-24) 1 $161 2021-12-16 Buy
TRC P571593 PKI(5-24),PKAInhibitor 500μg $95 2021-12-16 Buy

Properties

Density :1.54±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :Soluble in DMSO
form :Lyophilized
Water Solubility :Soluble in water

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

PKI PKA Inhibitor (5-24) is a synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase) (Ki = 2.3 nM) derived from the active site of the skeletal muscle inhibitor protein. It mimics the protein substrate by binding to the catalytic site through the arginine-cluster basic subsite. The prominent enzyme-substrate interaction site occurs where PKA catalytic subunit residues Tyr235 and Phe239 form a sandwich-like structure with residue Phe10 of PKI (5-24).

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