H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-HIS-ASP-OH
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- $55 - $1462
- Product name: H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-HIS-ASP-OH
- CAS: 99534-03-9
- MF: C94H148N32O31
- MW: 2222.38
- EINECS:
- MDL Number:MFCD00133989
- Synonyms:H-TTYADFIASGRTGRRNAIHD;H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-HIS-ASP-OH;CAMP DEPENDENT PK INHIBITOR (5-24);CAMP-DEPENDENT PROTEIN KINASE INHIBITOR (5-24);CAMP-DEPENDENT PROTEIN KINASE INHIBITOR-ALPHA (5-24) (HUMAN, MOUSE, RABBIT, RAT);ip20 ;TTYADFIASGRTGRRNAIHD;THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-HIS-ASP
13 prices
Selected condition:
Brand
- AK Scientific
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Tocris
- TRC
Package
- 1
- 500μg
- 1mg
- 5mg
- 10mg
- ManufacturerAK Scientific
- Product number2591CW
- Product description(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-4-Amino-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-carboxypropanoyl]amino]-3-phenylpropanoyl]amino]-3-methylpentanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-oxobutanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]butanedioicacid
- Packaging1mg
- Price$226
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2591CW
- Product description(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-4-Amino-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-carboxypropanoyl]amino]-3-phenylpropanoyl]amino]-3-methylpentanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-oxobutanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]butanedioicacid
- Packaging5mg
- Price$619
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb364468
- Product descriptioncAMP Dependent PK Inhibitor (5-24) > 95%
- Packaging1mg
- Price$462.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb364468
- Product descriptioncAMP Dependent PK Inhibitor (5-24) > 95%
- Packaging5mg
- Price$979.2
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb364468
- Product descriptioncAMP Dependent PK Inhibitor (5-24) > 95%
- Packaging10mg
- Price$1462
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15996
- Product descriptionPKA Inhibitor (5-24) ≥95%
- Packaging500μg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15996
- Product descriptionPKA Inhibitor (5-24) ≥95%
- Packaging1mg
- Price$94
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15996
- Product descriptionPKA Inhibitor (5-24) ≥95%
- Packaging5mg
- Price$385
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0021889
- Product descriptionPKI(5-24) 98.95%
- Packaging5mg
- Price$290
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0021889
- Product descriptionPKI(5-24) 98.95%
- Packaging10mg
- Price$490
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product number116805
- Product descriptionPKA Inhibitor 5-24 - CAS 99534-03-9 - Calbiochem
- Packaging500μg
- Price$214
- Updated2025-07-31
- Buy
- ManufacturerTocris
- Product number6221
- Product descriptionPKI(5-24)
- Packaging1
- Price$161
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberP571593
- Product descriptionPKI(5-24),PKAInhibitor
- Packaging500μg
- Price$95
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2591CW | (2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-4-Amino-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-carboxypropanoyl]amino]-3-phenylpropanoyl]amino]-3-methylpentanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-oxobutanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]butanedioicacid | 1mg | $226 | 2021-12-16 | Buy |
| AK Scientific | 2591CW | (2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-4-Amino-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-carboxypropanoyl]amino]-3-phenylpropanoyl]amino]-3-methylpentanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-oxobutanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]butanedioicacid | 5mg | $619 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb364468 | cAMP Dependent PK Inhibitor (5-24) > 95% | 1mg | $462.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb364468 | cAMP Dependent PK Inhibitor (5-24) > 95% | 5mg | $979.2 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb364468 | cAMP Dependent PK Inhibitor (5-24) > 95% | 10mg | $1462 | 2021-12-16 | Buy |
| Cayman Chemical | 15996 | PKA Inhibitor (5-24) ≥95% | 500μg | $55 | 2021-12-16 | Buy |
| Cayman Chemical | 15996 | PKA Inhibitor (5-24) ≥95% | 1mg | $94 | 2021-12-16 | Buy |
| Cayman Chemical | 15996 | PKA Inhibitor (5-24) ≥95% | 5mg | $385 | 2021-12-16 | Buy |
| ChemScene | CS-0021889 | PKI(5-24) 98.95% | 5mg | $290 | 2021-12-16 | Buy |
| ChemScene | CS-0021889 | PKI(5-24) 98.95% | 10mg | $490 | 2021-12-16 | Buy |
| Sigma-Aldrich | 116805 | PKA Inhibitor 5-24 - CAS 99534-03-9 - Calbiochem | 500μg | $214 | 2025-07-31 | Buy |
| Tocris | 6221 | PKI(5-24) | 1 | $161 | 2021-12-16 | Buy |
| TRC | P571593 | PKI(5-24),PKAInhibitor | 500μg | $95 | 2021-12-16 | Buy |
Properties
Density :1.54±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :Soluble in DMSO
form :Lyophilized
color :White to off-white
biological source :rabbit
Water Solubility :Soluble in water
Sequence :Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-His-Asp
storage temp. :−20°C
solubility :Soluble in DMSO
form :Lyophilized
color :White to off-white
biological source :rabbit
Water Solubility :Soluble in water
Sequence :Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-His-Asp
Safety Information
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Description
PKI PKA Inhibitor (5-24) is a synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase) (Ki = 2.3 nM) derived from the active site of the skeletal muscle inhibitor protein. It mimics the protein substrate by binding to the catalytic site through the arginine-cluster basic subsite. The prominent enzyme-substrate interaction site occurs where PKA catalytic subunit residues Tyr235 and Phe239 form a sandwich-like structure with residue Phe10 of PKI (5-24).Related product price
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$1.00 /1g
H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-HIS-ASP-OH CAS:99534-03-9
H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-HIS-ASP-OH CAS:99534-03-9




