Welcome to chemicalbook!
China English Japan Germany
010-86108875
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structure Search
RFQ
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook Sign in

Welcome back!

RFQ
skype
MY Account
Top
ChemicalBook >> CAS DataBase List >> ABC294640

ABC294640

ABC294640 price.
  • $44 - $3728.1
  • Product name: ABC294640
  • CAS: 915385-81-8
  • MF: C23H25ClN2O
  • MW: 380.91
  • EINECS:
  • MDL Number:MFCD22666355
  • Synonyms:ABC294640;3-(4-Chlorophenyl)-N-(4-pyridinylmethyl)tricyclo[3.3.1.1(3,7)]decane-1-carboxamide;Tricyclo[3.3.1.13,7]decane-1-carboxamide, 3-(4-chlorophenyl)-N-(4-pyridinylmethyl);ABC294640(Opaganib);3-(4-chlorophenyl)-adamantane-1-carboxylic acid (pyridin-4-ylmethyl)amide;ABC294640; ABC-294640; ABC 294640; 3-(4-CHLOROPHENYL)-ADAMANTANE-1-CARBOXYLIC ACID (PYRIDIN-4-YLMETHYL)AMIDE;OPAGANIB;CS-802;ABC294640;ABC-294640;ABC 294640;3-(4-CHLOROPHENYL)-ADAMANTANE-1-CARBOXYLIC ACID (PYRIDIN-4-YLMETHYL)AMIDE.
Price39 Properties Safety Information Description
39 prices
Selected condition：
Brand
  • Adipogen Life Sciences
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • Crysdot
  • CSNpharm
  • DC Chemicals
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3749-M025
  • Product descriptionOpaganib ≥98%(HPLC)
  • Packaging25mg
  • Price$360
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3749-M100
  • Product descriptionOpaganib ≥98%(HPLC)
  • Packaging100mg
  • Price$850
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA110039
  • Product descriptionABC294640 98+%
  • Packaging1mg
  • Price$44
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA110039
  • Product descriptionABC294640 98+%
  • Packaging5mg
  • Price$74
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA110039
  • Product descriptionABC294640 98+%
  • Packaging10mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA110039
  • Product descriptionABC294640 98+%
  • Packaging50mg
  • Price$182
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA110039
  • Product descriptionABC294640 98+%
  • Packaging100mg
  • Price$244
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA110039
  • Product descriptionABC294640 98+%
  • Packaging250mg
  • Price$510
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA110039
  • Product descriptionABC294640 98+%
  • Packaging1g
  • Price$1203
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0017247
  • Product descriptionABC-294640 95.00%
  • Packaging250MG
  • Price$3067.05
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0017247
  • Product descriptionABC-294640 95.00%
  • Packaging5MG
  • Price$504.17
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1182
  • Product descriptionABC294640
  • Packaging5mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1182
  • Product descriptionABC294640
  • Packaging25mg
  • Price$279
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1182
  • Product descriptionABC294640
  • Packaging100mg
  • Price$685
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS006710
  • Product descriptionABC294640 ≥98%
  • Packaging1mg
  • Price$44
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS006710
  • Product descriptionABC294640 ≥98%
  • Packaging5mg
  • Price$73
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3749-M025 Opaganib ≥98%(HPLC) 25mg $360 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-3749-M100 Opaganib ≥98%(HPLC) 100mg $850 2021-12-16 Buy
Ambeed A110039 ABC294640 98+% 1mg $44 2021-12-16 Buy
Ambeed A110039 ABC294640 98+% 5mg $74 2021-12-16 Buy
Ambeed A110039 ABC294640 98+% 10mg $108 2021-12-16 Buy
Ambeed A110039 ABC294640 98+% 50mg $182 2021-12-16 Buy
Ambeed A110039 ABC294640 98+% 100mg $244 2021-12-16 Buy
Ambeed A110039 ABC294640 98+% 250mg $510 2021-12-16 Buy
Ambeed A110039 ABC294640 98+% 1g $1203 2021-12-16 Buy
American Custom Chemicals Corporation API0017247 ABC-294640 95.00% 250MG $3067.05 2021-12-16 Buy
American Custom Chemicals Corporation API0017247 ABC-294640 95.00% 5MG $504.17 2021-12-16 Buy
ApexBio Technology B1182 ABC294640 5mg $85 2021-12-16 Buy
ApexBio Technology B1182 ABC294640 25mg $279 2021-12-16 Buy
ApexBio Technology B1182 ABC294640 100mg $685 2021-12-16 Buy
Arctom AS006710 ABC294640 ≥98% 1mg $44 2021-12-16 Buy
Arctom AS006710 ABC294640 ≥98% 5mg $73 2021-12-16 Buy
Next Last

Properties

Boiling point :589.5±50.0 °C(Predicted)
Density :1.273±0.06 g/cm3(Predicted)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :≥38.1 mg/mL in DMSO; insoluble in H2O; ≥58.9 mg/mL in EtOH
form :solid
pka :14.57±0.40(Predicted)
color :White to off-white
InChI :InChI=1S/C23H25ClN2O/c24-20-3-1-19(2-4-20)22-10-17-9-18(11-22)13-23(12-17,15-22)21(27)26-14-16-5-7-25-8-6-16/h1-8,17-18H,9-15H2,(H,26,27)
InChIKey :CAOTVXGYTWCKQE-UHFFFAOYSA-N
SMILES :C12(C(NCC3C=CN=CC=3)=O)CC3CC(CC(C4=CC=C(Cl)C=C4)(C3)C1)C2

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

ABC294640 is an inhibitor of sphingosine kinase 2 (SPHK2; Ki = 9.8 μM). It inhibits SPHK2 (IC50 = 60 μM) without affecting SPHK1 activity up to 100 μM but does reduce SPHK1 isoform a (SPHK1a) protein levels in androgen-independent LNCaP (LNCaP-AI) cells via an SPHK1-indirect, proteasomal-dependent mechanism when used at concentrations ranging from 5 to 25 μM. ABC294640 is inactive against a panel of 20 lipid-regulated kinases at 50 μM. It decreases sphingosine-1-phosphate (S1P) production in MDA-MB-231 cells in a concentration-dependent manner. ABC294640 inhibits proliferation of a variety of cancer cells, including HepG2 liver, A-498 kidney, PANC-1 pancreas, and HT-29 colon cells (IC50s = 6, 12.2, 32.8, and 48.1 μM, respectively). It reduces actin filament polymerization in, and cell migration of, A-498 cells in a scratch assay. Oral administration of ABC294640 (35 and 100 mg/kg every other day) reduces tumor growth in a mouse syngeneic model of mammary adenocarcinoma. It also reduces colonic inflammation in mouse and rat models of Crohn’s disease induced by trinitrobenzene sulfonic acid (TNBS).

More related product prices

Acetanilide

Related product price

Suppliers and manufacturers

career henan chemical co
ABC294640
$9.80 /1.79999995231628KG
ABC294640 CAS:915385-81-8
TargetMol Chemicals Inc.
Opaganib
$34.00 /1mg
Opaganib CAS:915385-81-8
ATK CHEMICAL COMPANY LIMITED
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd
Zibo Hangyu Biotechnology Development Co., Ltd
Aladdin Scientific