Ac-VDVAD-AFC
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- $76 - $926.2
- Product name: Ac-VDVAD-AFC
- CAS: 210344-94-8
- MF: C33H41F3N6O12
- MW: 770.71
- EINECS:
- MDL Number:MFCD04037014
- Synonyms:AC-VAL-ASP-VAL-ALA-ASP-7-AMINO-4-TRIFLUORO-METHYLCOUMARIN;AC-VAL-ASP-VAL-ALA-ASP-AFC;CASPASE 2 (ICH-1) SUBSTRATE 1F, FLUOROGENIC;N-ACETYL-VAL-ASP-VAL-ALA-ASP-7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN;BKQMJQIAIFEZJR-OIOUIRQFSA-N;3-[2-[[2-[[2-[(2-acetamido-3-methylbutanoyl)amino]-3-carboxypropanoyl]amino]-3-methylbutanoyl]amino]propanoylamino]-4-oxo-4-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]butanoic acid;L-α-Asparagine, N-acetyl-L-valyl-L-α-aspartyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]- (9CI);(4S,7S,10S,13S,16S)-7-(carboxymethyl)-4,10-diisopropyl-13-methyl-2,5,8,11,14-pentaoxo-16-((2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl)carbamoyl)-3,6,9,12,15-pentaazaoctadecan-18-oic acid
4 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- Cayman Chemical
Package
- 1mg
- 5MG
- 10mg
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0066712
- Product descriptionN-ACETYL-VAL-ASP-VAL-ALA-ASP-7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN 95.00%
- Packaging5MG
- Price$926.2
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14988
- Product descriptionAc-VDVAD-AFC ≥95%
- Packaging1mg
- Price$76
- Updated2022-04-27
- Buy
- ManufacturerCayman Chemical
- Product number14988
- Product descriptionAc-VDVAD-AFC ≥95%
- Packaging5mg
- Price$206
- Updated2022-04-27
- Buy
- ManufacturerCayman Chemical
- Product number14988
- Product descriptionAc-VDVAD-AFC ≥95%
- Packaging10mg
- Price$374
- Updated2022-04-27
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | HCH0066712 | N-ACETYL-VAL-ASP-VAL-ALA-ASP-7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN 95.00% | 5MG | $926.2 | 2021-12-16 | Buy |
| Cayman Chemical | 14988 | Ac-VDVAD-AFC ≥95% | 1mg | $76 | 2022-04-27 | Buy |
| Cayman Chemical | 14988 | Ac-VDVAD-AFC ≥95% | 5mg | $206 | 2022-04-27 | Buy |
| Cayman Chemical | 14988 | Ac-VDVAD-AFC ≥95% | 10mg | $374 | 2022-04-27 | Buy |
Properties
Boiling point :1137.178±65.00 °C(Press: 760.00 Torr)(predicted)
Density :1.403±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. :−20°C
solubility :DMSO/DMF: 20 mM
form :powder
pka :4.095±0.10(predicted)
Density :1.403±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. :−20°C
solubility :DMSO/DMF: 20 mM
form :powder
pka :4.095±0.10(predicted)
Safety Information
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Description
Ac-VDVAD-AFC is a fluorogenic substrate whose amino acids VDVAD have been shown to be a preferred cleavage site for caspase-2. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm. Increases in Ac-VDVAD-AFC cleavage have been reported to correlate with nitric oxide-induced activation of caspase-2 and subsequent apoptosis in human neuroblastoma lines.Suppliers and manufacturers
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