ACT-462206
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- $86.92 - $815
- Product name: ACT-462206
- CAS: 1361321-96-1
- MF: C20H24N2O4S
- MW: 388.48
- EINECS:-0
- MDL Number:MFCD28502270
- Synonyms:ACT-462206;(2S)-N-(3,5-DIMETHYLPHENYL)-1-(4-METHOXYPHENYL)SULFONYLPYRROLIDINE-2-CARBOXAMIDE;(2S)-N-(3,5-Dimethylphenyl)-1-[(4-methoxyphenyl)sulfonyl]-2-pyrrolidinecarboxamide;ACT-462206 >=98% (HPLC);ACT 462206,ACT462206;2-Pyrrolidinecarboxamide, N-(3,5-dimethylphenyl)-1-[(4-methoxyphenyl)sulfonyl]-, (2S)-;ACT-462206, 10 mM in DMSO
6 prices
Selected condition：
Brand
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50
- 2.5mg
- 5 mg
- 10mg
- 25 mg
- 10
- ManufacturerSigma-Aldrich
- Product numberSML1393
- Product descriptionACT-462206 ≥98% (HPLC)
- Packaging5 mg
- Price$86.92
- Updated2025-07-31
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1393
- Product descriptionACT-462206 ≥98% (HPLC)
- Packaging25 mg
- Price$272
- Updated2025-07-31
- Buy
- ManufacturerTocris
- Product number5319
- Product descriptionACT462206 ≥99%(HPLC)
- Packaging10
- Price$219
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number5319
- Product descriptionACT462206 ≥99%(HPLC)
- Packaging50
- Price$815
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberA305313
- Product descriptionACT462206
- Packaging2.5mg
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number254538
- Product descriptionACT 462206
- Packaging10mg
- Price$495
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1393 | ACT-462206 ≥98% (HPLC) | 5 mg | $86.92 | 2025-07-31 | Buy |
| Sigma-Aldrich | SML1393 | ACT-462206 ≥98% (HPLC) | 25 mg | $272 | 2025-07-31 | Buy |
| Tocris | 5319 | ACT462206 ≥99%(HPLC) | 10 | $219 | 2021-12-16 | Buy |
| Tocris | 5319 | ACT462206 ≥99%(HPLC) | 50 | $815 | 2021-12-16 | Buy |
| TRC | A305313 | ACT462206 | 2.5mg | $220 | 2021-12-16 | Buy |
| Usbiological | 254538 | ACT 462206 | 10mg | $495 | 2021-12-16 | Buy |
Properties
Density :1.285±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO
pka :14.27±0.70(Predicted)
form :Solid
color :White to off-white
InChI :1S/C20H24N2O4S/c1-14-11-15(2)13-16(12-14)21-20(23)19-5-4-10-22(19)27(24,25)18-8-6-17(26-3)7-9-18/h6-9,11-13,19H,4-5,10H2,1-3H3,(H,21,23)/t19-/m0/s1
InChIKey :NHPQGZOBHSVTAQ-IBGZPJMESA-N
SMILES :O=S(N1CCC[C@H]1C(NC2=CC(C)=CC(C)=C2)=O)(C3=CC=C(OC)C=C3)=O
storage temp. :Store at -20°C
solubility :Soluble in DMSO
pka :14.27±0.70(Predicted)
form :Solid
color :White to off-white
InChI :1S/C20H24N2O4S/c1-14-11-15(2)13-16(12-14)21-20(23)19-5-4-10-22(19)27(24,25)18-8-6-17(26-3)7-9-18/h6-9,11-13,19H,4-5,10H2,1-3H3,(H,21,23)/t19-/m0/s1
InChIKey :NHPQGZOBHSVTAQ-IBGZPJMESA-N
SMILES :O=S(N1CCC[C@H]1C(NC2=CC(C)=CC(C)=C2)=O)(C3=CC=C(OC)C=C3)=O
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
ACT-462206 is a potent and selective dual orexin receptor antagonist (DORA) that inhibits the stimulating effects of the orexin peptides at both the orexin 1 and 2 receptors. It decreases wakefulness and increases non-rapid eye movement (non-REM) and REM sleep while maintaining natural sleep architectures in some animal models while showing anxiolytic-like properties without affecting cognition and motor function in others.Suppliers and manufacturers
TargetMol Chemicals Inc.
Aladdin Scientific
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
HangZhou YuHao Chemical Technology Co., Ltd.
Shanghai JiYi Biotechnology Co. Ltd.
Shanghai YuanYe Biotechnology Co., Ltd.
MQ (shanghai) Pharmaceuticals Co., Ltd.
Jinan Yaoyan Pharmaceutical Co., Ltd.
Angel Pharmatech, Ltd.
Shanghai Hongye Biotechnology Co. Ltd