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ChemicalBook >> CAS DataBase List >> ACY-1215

ACY-1215

ACY-1215 price.
  • $28 - $2395.3
  • Product name: ACY-1215
  • CAS: 1316214-52-4
  • MF: C24H27N5O3
  • MW: 433.5
  • EINECS:
  • MDL Number:MFCD22666356
  • Synonyms:Rocilinostat (ACY-1215);2-(Diphenylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]-5-pyrimidinecarboxamide;ACY 63;2-(DiphenylaMino)-N-(7-(hydroxyaMino)-7-oxoheptyl)pyriMidine-5-carboxaMide;Rocilinostat, >=99%;5-Pyrimidinecarboxamide, 2-(diphenylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]-;2-(Diphenylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]-5-pyrimidinecarboxamide ACY 1215;Ricolinostat
Price27 Properties Safety Information Description
27 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1unit
  • 5MG
  • 10mg
  • 20mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 1000mg
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product numberX5832
  • Product descriptionACY-1215
  • Packaging100mg
  • Price$232
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001873
  • Product descriptionACY-1215 95.00%
  • Packaging5MG
  • Price$251.9
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4083
  • Product descriptionRocilinostat(ACY-1215)
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4083
  • Product descriptionRocilinostat(ACY-1215)
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4083
  • Product descriptionRocilinostat(ACY-1215)
  • Packaging10mM(in 1mL DMSO)
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4083
  • Product descriptionRocilinostat(ACY-1215)
  • Packaging10mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4083
  • Product descriptionRocilinostat(ACY-1215)
  • Packaging50mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4083
  • Product descriptionRocilinostat(ACY-1215)
  • Packaging200mg
  • Price$850
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60110
  • Product descriptionRicolinostat(ACY-1215) ≥98%
  • Packaging20mg
  • Price$138
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180914
  • Product descriptionRocilinostat (ACY-1215) >98%
  • Packaging100mg
  • Price$690.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180914
  • Product descriptionRocilinostat (ACY-1215) >98%
  • Packaging250mg
  • Price$1283.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180914
  • Product descriptionRocilinostat (ACY-1215) >98%
  • Packaging1000mg
  • Price$2395.3
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBA164806
  • Product descriptionACY 1215
  • Packaging10mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBA164806
  • Product descriptionACY 1215
  • Packaging50mg
  • Price$297.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21531
  • Product descriptionACY-1215 ≥98%
  • Packaging25mg
  • Price$72
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21531
  • Product descriptionACY-1215 ≥98%
  • Packaging50mg
  • Price$129
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X5832 ACY-1215 100mg $232 2021-12-16 Buy
American Custom Chemicals Corporation INB0001873 ACY-1215 95.00% 5MG $251.9 2021-12-16 Buy
ApexBio Technology A4083 Rocilinostat(ACY-1215) 1unit $28 2021-12-16 Buy
ApexBio Technology A4083 Rocilinostat(ACY-1215) 5mg $70 2021-12-16 Buy
ApexBio Technology A4083 Rocilinostat(ACY-1215) 10mM(in 1mL DMSO) $75 2021-12-16 Buy
ApexBio Technology A4083 Rocilinostat(ACY-1215) 10mg $100 2021-12-16 Buy
ApexBio Technology A4083 Rocilinostat(ACY-1215) 50mg $280 2021-12-16 Buy
ApexBio Technology A4083 Rocilinostat(ACY-1215) 200mg $850 2021-12-16 Buy
Arctom CFN60110 Ricolinostat(ACY-1215) ≥98% 20mg $138 2021-12-16 Buy
Biorbyt Ltd orb180914 Rocilinostat (ACY-1215) >98% 100mg $690.2 2021-12-16 Buy
Biorbyt Ltd orb180914 Rocilinostat (ACY-1215) >98% 250mg $1283.5 2021-12-16 Buy
Biorbyt Ltd orb180914 Rocilinostat (ACY-1215) >98% 1000mg $2395.3 2021-12-16 Buy
Biosynth Carbosynth BA164806 ACY 1215 10mg $85 2021-12-16 Buy
Biosynth Carbosynth BA164806 ACY 1215 50mg $297.5 2021-12-16 Buy
Cayman Chemical 21531 ACY-1215 ≥98% 25mg $72 2024-03-01 Buy
Cayman Chemical 21531 ACY-1215 ≥98% 50mg $129 2024-03-01 Buy
Next Last

Properties

Melting point :189 - 191°C
Density :1.239±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly)
pka :9.47±0.20(Predicted)
form :Solid
color :White to Off-White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

ACY-1215 is an inhibitor of histone deacetylase 6 (HDAC6; IC50 = 5 nM). It is at least 10-fold less active against other HDACs in enzymatic assays. ACY-1215 shows synergistic activity with the proteasome inhibitor bortezomib against multiple myeloma (MM) cells, inducing protracted endoplasmic reticulum stress and apoptosis. ACY-1215 combined with proteasome inhibitors suppresses tumor growth and increases survival in mice with MM and mantle cell lymphoma xenografts. A multicenter phase I trial examining ACY-1215 combined with the E3 ligase inhibitor lenalidomide and dexamethasone in multiple myeloma found inhibition of HDAC6 in vivo. ACY-1215 also diminishes liver cyst development and fibrosis in a rat model of polycystic liver disease.

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Suppliers and manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
ACY-1215
$0.00 /25kg
ACY-1215 CAS:1316214-52-4
TargetMol Chemicals Inc.
Ricolinostat
$44.00 /5mg
Ricolinostat CAS:1316214-52-4
Capot Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
Biochempartner
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BOC Sciences
Alchem Pharmtech,Inc.
HANGZHOU CLAP TECHNOLOGY CO.,LTD