AF12198
|
- $110 - $2384
- Product name: AF12198
- CAS: 185413-30-3
- MF: C96H123N19O22
- MW: 1895.12
- EINECS:
- MDL Number:MFCD02259571
- Synonyms:AF12198;AC-PHE-GLU-TRP-THR-PRO-GLY-TRP-TYR-GLN-AZE-TYR-ALA-LEU-PRO-LEU-NH2;AC-PHE-GLU-TRP-THR-PRO-GLY-TRP-TYR-GLN-L-AZETIDINE-2-CARBONYL-TYR-ALA-LEU-PRO-LEU-NH2;AC-PHE-GLU-TRP-THR-PRO-GLY-TRP-TYR-GLN-L-AZETIDINE-2-CARBOXYLIC ACID-TYR-ALA-LEU-PRO-LEU-NH2;L-Leucinamide, N-acetyl-L-phenylalanyl-L-α-glutamyl-L-tryptophyl-L-threonyl-L-prolylglycyl-L-tryptophyl-L-tyrosyl-L-glutaminyl-(2S)-2-azetidinecarbonyl-L-tyrosyl-L-alanyl-L-leucyl-L-prolyl-;Ac-FEWTPGWYQ（Aze）YALPL-NH2;AF12198（TFA）;AF12198, human type I interleukin receptor antagonist
20 prices
Selected condition：
Brand
- aablocks
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth
- DC Chemicals
- Medical Isotopes, Inc.
- Tocris
- TRC
- Usbiological
Package
- 50ug
- 100ug
- 500ug
- 1mg
- 1
- 250ug
- 5mg
- 10mg
- 25mg
- 50mg
- Manufactureraablocks
- Product numberAA00ACEF
- Product descriptionAF 12198 ≥98%
- Packaging1mg
- Price$239
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ACEF
- Product descriptionAF 12198 ≥98%
- Packaging5mg
- Price$636
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ACEF
- Product descriptionAF 12198 ≥98%
- Packaging10mg
- Price$1060
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ACEF
- Product descriptionAF 12198 ≥98%
- Packaging25mg
- Price$1695
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ACEF
- Product descriptionAF 12198 ≥98%
- Packaging50mg
- Price$2384
- Updated2026-05-28
- Buy
- ManufacturerAK Scientific
- Product number2681CW
- Product description(4S)-4-[[(2S)-2-Acetamido-3-phenylpropanoyl]amino]-5-[[(2S)-1-[[(2S,3R)-1-[(2S)-2-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoyl]azetidin-1-yl]-1,5-dioxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-oxopentanoicacid
- Packaging1mg
- Price$1737
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPEP0004562
- Product descriptionAF12198 95.00%
- Packaging1MG
- Price$830.74
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5175
- Product descriptionAF12198
- Packaging1mg
- Price$511
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5175
- Product descriptionAF 12198
- Packaging1mg
- Price$110
- Updated2026-05-06
- Buy
- ManufacturerBiosynth
- Product numberFA109195
- Product descriptionAc-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-L-azetidine-2-carbonyl-Tyr-Ala-Leu-Pro-Leu-NH2
- Packaging50ug
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFA109195
- Product descriptionAc-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-L-azetidine-2-carbonyl-Tyr-Ala-Leu-Pro-Leu-NH2
- Packaging100ug
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFA109195
- Product descriptionAc-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-L-azetidine-2-carbonyl-Tyr-Ala-Leu-Pro-Leu-NH2
- Packaging500ug
- Price$775
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFA109195
- Product descriptionAc-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-L-azetidine-2-carbonyl-Tyr-Ala-Leu-Pro-Leu-NH2
- Packaging1mg
- Price$1250
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFA109195
- Product descriptionAc-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-L-azetidine-2-carbonyl-Tyr-Ala-Leu-Pro-Leu-NH2
- Packaging250ug
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC41586
- Product descriptionAF12198 >98%
- Packaging25mg
- Price$990
- Updated2026-05-24
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number67690
- Product descriptionAF12198
- Packaging25mg
- Price$2320
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00ACEF | AF 12198 ≥98% | 1mg | $239 | 2026-05-28 | Buy |
| aablocks | AA00ACEF | AF 12198 ≥98% | 5mg | $636 | 2026-05-28 | Buy |
| aablocks | AA00ACEF | AF 12198 ≥98% | 10mg | $1060 | 2026-05-28 | Buy |
| aablocks | AA00ACEF | AF 12198 ≥98% | 25mg | $1695 | 2026-05-28 | Buy |
| aablocks | AA00ACEF | AF 12198 ≥98% | 50mg | $2384 | 2026-05-28 | Buy |
| AK Scientific | 2681CW | (4S)-4-[[(2S)-2-Acetamido-3-phenylpropanoyl]amino]-5-[[(2S)-1-[[(2S,3R)-1-[(2S)-2-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoyl]azetidin-1-yl]-1,5-dioxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-oxopentanoicacid | 1mg | $1737 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PEP0004562 | AF12198 95.00% | 1MG | $830.74 | 2021-12-16 | Buy |
| ApexBio Technology | B5175 | AF12198 | 1mg | $511 | 2021-12-16 | Buy |
| ApexBio Technology | B5175 | AF 12198 | 1mg | $110 | 2026-05-06 | Buy |
| Biosynth | FA109195 | Ac-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-L-azetidine-2-carbonyl-Tyr-Ala-Leu-Pro-Leu-NH2 | 50ug | $200 | 2021-12-16 | Buy |
| Biosynth | FA109195 | Ac-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-L-azetidine-2-carbonyl-Tyr-Ala-Leu-Pro-Leu-NH2 | 100ug | $300 | 2021-12-16 | Buy |
| Biosynth | FA109195 | Ac-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-L-azetidine-2-carbonyl-Tyr-Ala-Leu-Pro-Leu-NH2 | 500ug | $775 | 2021-12-16 | Buy |
| Biosynth | FA109195 | Ac-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-L-azetidine-2-carbonyl-Tyr-Ala-Leu-Pro-Leu-NH2 | 1mg | $1250 | 2021-12-16 | Buy |
| Biosynth | FA109195 | Ac-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-L-azetidine-2-carbonyl-Tyr-Ala-Leu-Pro-Leu-NH2 | 250ug | $500 | 2021-12-16 | Buy |
| DC Chemicals | DC41586 | AF12198 >98% | 25mg | $990 | 2026-05-24 | Buy |
| Medical Isotopes, Inc. | 67690 | AF12198 | 25mg | $2320 | 2021-12-16 | Buy |
Properties
Melting point :>179°C (dec.)
Density :1.353±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMSO (Slightly), Methanol (Slightly), Water (Very Slightly)
pka :4.44±0.10(Predicted)
form :solid
color :White to Off-White
Sequence :Ac-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-{Aze}-Tyr-Ala-Leu-Pro-Leu-NH2
Density :1.353±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMSO (Slightly), Methanol (Slightly), Water (Very Slightly)
pka :4.44±0.10(Predicted)
form :solid
color :White to Off-White
Sequence :Ac-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-{Aze}-Tyr-Ala-Leu-Pro-Leu-NH2
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
AF 12198 is a peptide that selectively binds Interleukin-1 (IL-1) receptor and blocks in vivo responses to IL-1 (1). The interleukin-1 receptor can activate the innate immune response by binding to cytokines (2). Dysregulation of cytokine production can lead to aberrant immune cells activation that could result in auto-inflammatory disorders.More related product prices
Related product price
-
AZETIDINE-2-CARBOXAMIDE
$88-2297 -
2-Azetidinemethanamine
$60-4890 -
AF12198
$110-2384
Suppliers and manufacturers
Shenzhen Nexconn Pharmatechs Ltd
BOC Sciences
Zhejiang J&C Biological Technology Co.,Limited
Chengdu Youngshe Chemical Co., Ltd.
Nanjing TGpeptide
Aladdin Scientific
Changsha MOL Changes Biotechnology Co., Ltd.
LEON (NANJING) BIOTECHNOLOGY CO., LTD.
3B Pharmachem (Wuhan) International Co.,Ltd.
GL Biochem (Shanghai) Ltd