ANTALARMIN HYDROCHLORIDE
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- $110 - $935
- Product name: ANTALARMIN HYDROCHLORIDE
- CAS: 220953-69-5
- MF: C24H35ClN4
- MW: 415.02
- EINECS:
- MDL Number:MFCD05664721
- Synonyms:ANTALARMIN HYDROCHLORIDE;N-BUTYL-N-ETHYL-2,5,6-TRIMETHYL-7-(2,4,6-TRIMETHYLPHENYL)-7H-PYRROLOL[2,3-D]PYRIMIDIN-4-AMINE HYDROCHLORIDE;N-Butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolol[2,3-d]pyrimidin-4-amine hydrochloride;N-Butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-aminehydrochloride;7H-Pyrrolo[2,3-d]pyrimidin-4-amine,N-butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-,hydrochloride;Antalarmin hydrochlo;7H-Pyrrolo[2,3-d]pyrimidin-4-amine,N-butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-, hydrochloride (1:1);N-Butyl-N-ethyl-7-mesityl-2,5,6-trimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine hydrochloride
14 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Sigma-Aldrich
- Tocris
- TRC
Package
- 50
- 5mg
- 10mg
- 25mg
- 10
- 50mg
- ManufacturerAK Scientific
- Product number2244CW
- Product descriptionAntalarmin hydrochloride
- Packaging25mg
- Price$460
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2244CW
- Product descriptionAntalarmin hydrochloride
- Packaging10mg
- Price$268
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004701
- Product descriptionANTALARMIN 95.00%
- Packaging10MG
- Price$708.87
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7184
- Product descriptionAntalarmin hydrochloride
- Packaging10mg
- Price$263
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7184
- Product descriptionAntalarmin hydrochloride
- Packaging50mg
- Price$935
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15147
- Product descriptionAntalarmin (hydrochloride) ≥98%
- Packaging5mg
- Price$110
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15147
- Product descriptionAntalarmin (hydrochloride) ≥98%
- Packaging10mg
- Price$153
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15147
- Product descriptionAntalarmin (hydrochloride) ≥98%
- Packaging25mg
- Price$326
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15147
- Product descriptionAntalarmin (hydrochloride) ≥98%
- Packaging50mg
- Price$542
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberA8727
- Product descriptionAntalarmin hydrochloride ≥98% (HPLC), solid
- Packaging50mg
- Price$924
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberA8727
- Product descriptionAntalarmin hydrochloride ≥98% (HPLC), solid
- Packaging10mg
- Price$270
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number2778
- Product descriptionAntalarmin hydrochloride ≥99%(HPLC)
- Packaging10
- Price$216
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number2778
- Product descriptionAntalarmin hydrochloride ≥99%(HPLC)
- Packaging50
- Price$876
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberA678415
- Product descriptionAntalarmin hydrochloride
- Packaging25mg
- Price$265
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2244CW | Antalarmin hydrochloride | 25mg | $460 | 2021-12-16 | Buy |
| AK Scientific | 2244CW | Antalarmin hydrochloride | 10mg | $268 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004701 | ANTALARMIN 95.00% | 10MG | $708.87 | 2021-12-16 | Buy |
| ApexBio Technology | B7184 | Antalarmin hydrochloride | 10mg | $263 | 2021-12-16 | Buy |
| ApexBio Technology | B7184 | Antalarmin hydrochloride | 50mg | $935 | 2021-12-16 | Buy |
| Cayman Chemical | 15147 | Antalarmin (hydrochloride) ≥98% | 5mg | $110 | 2024-03-01 | Buy |
| Cayman Chemical | 15147 | Antalarmin (hydrochloride) ≥98% | 10mg | $153 | 2024-03-01 | Buy |
| Cayman Chemical | 15147 | Antalarmin (hydrochloride) ≥98% | 25mg | $326 | 2024-03-01 | Buy |
| Cayman Chemical | 15147 | Antalarmin (hydrochloride) ≥98% | 50mg | $542 | 2024-03-01 | Buy |
| Sigma-Aldrich | A8727 | Antalarmin hydrochloride ≥98% (HPLC), solid | 50mg | $924 | 2024-03-01 | Buy |
| Sigma-Aldrich | A8727 | Antalarmin hydrochloride ≥98% (HPLC), solid | 10mg | $270 | 2024-03-01 | Buy |
| Tocris | 2778 | Antalarmin hydrochloride ≥99%(HPLC) | 10 | $216 | 2021-12-16 | Buy |
| Tocris | 2778 | Antalarmin hydrochloride ≥99%(HPLC) | 50 | $876 | 2021-12-16 | Buy |
| TRC | A678415 | Antalarmin hydrochloride | 25mg | $265 | 2021-12-16 | Buy |
Properties
storage temp. :2-8°C
solubility :DMSO: ~24 mg/mL, soluble
form :solid
color :off-white
InChI :InChI=1S/C24H34N4.ClH/c1-9-11-12-27(10-2)23-21-18(6)19(7)28(24(21)26-20(8)25-23)22-16(4)13-15(3)14-17(22)5;/h13-14H,9-12H2,1-8H3;1H
InChIKey :CGDGXEDXEXACKQ-UHFFFAOYSA-N
SMILES :CC1=C(C2C(=NC(C)=NC=2N1C1C(=CC(C)=CC=1C)C)N(CC)CCCC)C.Cl
solubility :DMSO: ~24 mg/mL, soluble
form :solid
color :off-white
InChI :InChI=1S/C24H34N4.ClH/c1-9-11-12-27(10-2)23-21-18(6)19(7)28(24(21)26-20(8)25-23)22-16(4)13-15(3)14-17(22)5;/h13-14H,9-12H2,1-8H3;1H
InChIKey :CGDGXEDXEXACKQ-UHFFFAOYSA-N
SMILES :CC1=C(C2C(=NC(C)=NC=2N1C1C(=CC(C)=CC=1C)C)N(CC)CCCC)C.Cl
Safety Information
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Description
Corticotropin-releasing hormone (CRH) secreted from the hypothalamus is the major regulator of pituitary corticotropin-release and consequent glucocorticoid secretion. Antalarmin is a selective, nonpeptide antagonist of the CRH receptor 1 (Ki = 1 nM) that, consequently, reduces the release of corticotropin in response to chronic stress. Through its antagonism of central CRH signaling, antalarmin can reduce endocrinological, cardiovascular, and behavioral responses to stressful stimuli. It has also been shown to reduce dose escalation in cocaine-addicted rats, to produce anti-inflammatory effects in arthritis models, and to suppress stress-induced gastric ulceration related to irritable bowel syndrome.Suppliers and manufacturers
Henan Tianfu Chemical Co.,Ltd.
Nantong HI-FUTURE Biology Co., Ltd.
Aladdin Scientific
DAYANG CHEM (HANGZHOU) CO.,LTD
Nantong Hi-Future Biotechnology Co., Ltd
3B Pharmachem (Wuhan) International Co.,Ltd.
Sigma-Aldrich
EMMX Biotechnology LLC
Shanghai EFE Biological Technology Co., Ltd.
