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ChemicalBook >> CAS DataBase List >> AZD8186

AZD8186

AZD8186 price.
  • $8 - $1800
  • Product name: AZD8186
  • CAS: 1627494-13-6
  • MF: C24H25F2N3O4
  • MW: 457.47
  • EINECS:-0
  • MDL Number:MFCD27987908
  • Synonyms:AZD8186;AZD 8186, >=98%;(R)-8-(1-(3,5-difluorophenylamino)ethyl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide;8-[(1R)-1-[(3,5-Difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-6-carboxamide;AZD8186;AZD-8186;AZD 8186;CS-1576;8-(1-((3,5-difluorophenyl)amino)ethyl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide;AZD-8186;AZD 8186
Price40 Properties Safety Information Description
40 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TRC
Package
  • 5mg
  • 10mg
  • 1mg
  • 10mM*1mLinDMSO
  • 25mg
  • 50mg
  • 100.00mg
  • 100mg
  • 250mg
  • 250.00mg
  • 1G
  • 1.00g
  • 5G
  • Manufactureraablocks
  • Product numberAA001TBB
  • Product description8-[(1R)-1-[(3,5-difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-6-carboxamide 95%
  • Packaging100mg
  • Price$57
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001TBB
  • Product description8-[(1R)-1-[(3,5-difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-6-carboxamide 95%
  • Packaging250mg
  • Price$79
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001TBB
  • Product description8-[(1R)-1-[(3,5-difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-6-carboxamide ≥98%
  • Packaging50mg
  • Price$38
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001TBB
  • Product description8-[(1R)-1-[(3,5-difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-6-carboxamide ≥98%
  • Packaging25mg
  • Price$21
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001TBB
  • Product description8-[(1R)-1-[(3,5-difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-6-carboxamide 99%
  • Packaging10mg
  • Price$13
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001TBB
  • Product description8-[(1R)-1-[(3,5-difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-6-carboxamide ≥98%
  • Packaging5mg
  • Price$10
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001TBB
  • Product description8-[(1R)-1-[(3,5-difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-6-carboxamide 99%
  • Packaging1mg
  • Price$8
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberL14957
  • Product descriptionazd-8186 98%
  • Packaging250MG
  • Price$110
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberL14957
  • Product descriptionazd-8186 98%
  • Packaging1G
  • Price$395
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberL14957
  • Product descriptionazd-8186 98%
  • Packaging5G
  • Price$1220
  • Updated2026-05-27
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0002592
  • Product description(R)-8-(1-((3,5-DIFLUOROPHENYL)AMINO)ETHYL)-N,N-DIMETHYL-2-MORPHOLINO-4-OXO-4H-CHROMENE-6-CARBOXAMIDE 95.00%
  • Packaging5MG
  • Price$451.47
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5950
  • Product descriptionAZD8186
  • Packaging5mg
  • Price$106
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5950
  • Product descriptionAZD8186
  • Packaging25mg
  • Price$358
  • Updated2026-05-06
  • Buy
  • ManufacturerBiosynth
  • Product numberFD103345
  • Product descriptionAZD 8186
  • Packaging5mg
  • Price$250
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFD103345
  • Product descriptionAZD 8186
  • Packaging10mg
  • Price$388.3
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFD103345
  • Product descriptionAZD 8186
  • Packaging25mg
  • Price$776.75
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA001TBB 8-[(1R)-1-[(3,5-difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-6-carboxamide 95% 100mg $57 2026-05-28 Buy
aablocks AA001TBB 8-[(1R)-1-[(3,5-difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-6-carboxamide 95% 250mg $79 2026-05-28 Buy
aablocks AA001TBB 8-[(1R)-1-[(3,5-difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-6-carboxamide ≥98% 50mg $38 2026-05-28 Buy
aablocks AA001TBB 8-[(1R)-1-[(3,5-difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-6-carboxamide ≥98% 25mg $21 2026-05-28 Buy
aablocks AA001TBB 8-[(1R)-1-[(3,5-difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-6-carboxamide 99% 10mg $13 2026-05-28 Buy
aablocks AA001TBB 8-[(1R)-1-[(3,5-difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-6-carboxamide ≥98% 5mg $10 2026-05-28 Buy
aablocks AA001TBB 8-[(1R)-1-[(3,5-difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-6-carboxamide 99% 1mg $8 2026-05-28 Buy
ACHEMBLOCK L14957 azd-8186 98% 250MG $110 2026-05-27 Buy
ACHEMBLOCK L14957 azd-8186 98% 1G $395 2026-05-27 Buy
ACHEMBLOCK L14957 azd-8186 98% 5G $1220 2026-05-27 Buy
American Custom Chemicals Corporation KIN0002592 (R)-8-(1-((3,5-DIFLUOROPHENYL)AMINO)ETHYL)-N,N-DIMETHYL-2-MORPHOLINO-4-OXO-4H-CHROMENE-6-CARBOXAMIDE 95.00% 5MG $451.47 2021-12-16 Buy
ApexBio Technology B5950 AZD8186 5mg $106 2026-05-06 Buy
ApexBio Technology B5950 AZD8186 25mg $358 2026-05-06 Buy
Biosynth FD103345 AZD 8186 5mg $250 2026-06-04 Buy
Biosynth FD103345 AZD 8186 10mg $388.3 2026-06-04 Buy
Biosynth FD103345 AZD 8186 25mg $776.75 2026-06-04 Buy
Next Last

Properties

Melting point :226-227°C
Boiling point :645.2±55.0 °C(Predicted)
Density :1.351±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
pka :2.56±0.50(Predicted)
form :Solid
color :White to Off-White
InChI :InChI=1S/C24H25F2N3O4/c1-14(27-18-11-16(25)10-17(26)12-18)19-8-15(24(31)28(2)3)9-20-21(30)13-22(33-23(19)20)29-4-6-32-7-5-29/h8-14,27H,4-7H2,1-3H3/t14-/m1/s1
InChIKey :LMJFJIDLEAWOQJ-CQSZACIVSA-N
SMILES :C1(N2CCOCC2)OC2=C([C@H](NC3=CC(F)=CC(F)=C3)C)C=C(C(N(C)C)=O)C=C2C(=O)C=1

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

AZD 8186 is a potent and selective inhibitor of PI3Kβ and PI3Kδ for the treatment of PTEN-deficient cancers.

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Suppliers and manufacturers

Shanghai Taibao Pharmaceutical Technology Co., Ltd. Kaixin Chemical (Hong Kong) Limited Shanghai Boyle Chemical Co., Ltd. Chembest Research Laboratories Limited Shanghai Hanhong Scientific Co.,Ltd. Dalian Meilun Biotech Co., Ltd. Haoyuan Chemexpress Co., Ltd. ShangHai Caerulum Pharma Discovery Co., Ltd. Suzhou Sino Rare Chemical Co., Ltd. Bide Pharmatech Ltd.