Adapalene
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- $6 - $1504.5
- Product name: Adapalene
- CAS: 106685-40-9
- MF: C28H28O3
- MW: 412.52
- EINECS:620-513-9
- MDL Number:MFCD03106112
- Synonyms:ADAPALENE;6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTHOIC ACID;6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic Acid;CD-271;Differi;6-[4-Methoxy-3-(adamantan-1-yl)phenyl]-2-naphthalenecarboxylic acid;6-[3-(adaMantan-1-yl)-4-Methoxyphenyl]naphthalene-2-carboxylic acid;[1]6-[4-Methoxy-3-(tricyclo[3.3.1.1~3,7~]dec-1-yl)phenyl]naphthalene-2-carboxylic acid
68 prices
Selected condition：
Brand
- AHH
- AK Scientific
- Alfa Aesar
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- y0001119
- 10mg
- 200MG
- 500mg
- 50
- y0001121
- 2g
- 5g
- 10
- 25mg
- 100mg
- 250mg
- 1g
- 10g
- 50mg
- 0.25G
- 25g
- 10mM(in 1mL DMSO)
- ManufacturerAHH
- Product numberAPI-1690
- Product descriptionAdapalene 98%
- Packaging1g
- Price$610
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberI810
- Product descriptionAdapalene
- Packaging100mg
- Price$39
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ50424
- Product descriptionAdapalene
- Packaging250mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberI810
- Product descriptionAdapalene
- Packaging250mg
- Price$61
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ50424
- Product descriptionAdapalene
- Packaging1g
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberI810
- Product descriptionAdapalene
- Packaging1g
- Price$167
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberI810
- Product descriptionAdapalene
- Packaging10g
- Price$667
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ67025
- Product descriptionAdapalene
- Packaging25mg
- Price$117
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ67025
- Product descriptionAdapalene
- Packaging50mg
- Price$144
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105293
- Product description6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoicacid 99+%
- Packaging50mg
- Price$6
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105293
- Product description6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoicacid 99+%
- Packaging100mg
- Price$10
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105293
- Product description6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoicacid 99+%
- Packaging250mg
- Price$13
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105293
- Product description6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoicacid 99+%
- Packaging1g
- Price$13
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105293
- Product description6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoicacid 99+%
- Packaging25g
- Price$441
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0001385
- Product descriptionAdapalene 95.00%
- Packaging0.25G
- Price$407
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1267
- Product descriptionAdapalene
- Packaging50mg
- Price$50
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | API-1690 | Adapalene 98% | 1g | $610 | 2021-12-16 | Buy |
| AK Scientific | I810 | Adapalene | 100mg | $39 | 2021-12-16 | Buy |
| AK Scientific | J50424 | Adapalene | 250mg | $45 | 2021-12-16 | Buy |
| AK Scientific | I810 | Adapalene | 250mg | $61 | 2021-12-16 | Buy |
| AK Scientific | J50424 | Adapalene | 1g | $125 | 2021-12-16 | Buy |
| AK Scientific | I810 | Adapalene | 1g | $167 | 2021-12-16 | Buy |
| AK Scientific | I810 | Adapalene | 10g | $667 | 2021-12-16 | Buy |
| Alfa Aesar | J67025 | Adapalene | 25mg | $117 | 2021-12-16 | Buy |
| Alfa Aesar | J67025 | Adapalene | 50mg | $144 | 2021-12-16 | Buy |
| Ambeed | A105293 | 6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoicacid 99+% | 50mg | $6 | 2021-12-16 | Buy |
| Ambeed | A105293 | 6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoicacid 99+% | 100mg | $10 | 2021-12-16 | Buy |
| Ambeed | A105293 | 6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoicacid 99+% | 250mg | $13 | 2021-12-16 | Buy |
| Ambeed | A105293 | 6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoicacid 99+% | 1g | $13 | 2021-12-16 | Buy |
| Ambeed | A105293 | 6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoicacid 99+% | 25g | $441 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0001385 | Adapalene 95.00% | 0.25G | $407 | 2021-12-16 | Buy |
| ApexBio Technology | A1267 | Adapalene | 50mg | $50 | 2021-12-16 | Buy |
Properties
Melting point :319-3220C
Boiling point :606.3±55.0 °C(Predicted)
Density :1.233±0.06 g/cm3(Predicted)
RTECS :QJ1987000
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :4.2(at 25℃)
form :White solid
color :white to off-white
Merck :14,150
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months
InChIKey :LZCDAPDGXCYOEH-UHFFFAOYSA-N
SMILES :C1=C2C(C=C(C3=CC=C(OC)C(C45CC6CC(CC(C6)C4)C5)=C3)C=C2)=CC=C1C(O)=O
CAS DataBase Reference :106685-40-9(CAS DataBase Reference)
Boiling point :606.3±55.0 °C(Predicted)
Density :1.233±0.06 g/cm3(Predicted)
RTECS :QJ1987000
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :4.2(at 25℃)
form :White solid
color :white to off-white
Merck :14,150
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months
InChIKey :LZCDAPDGXCYOEH-UHFFFAOYSA-N
SMILES :C1=C2C(C=C(C3=CC=C(OC)C(C45CC6CC(CC(C6)C4)C5)=C3)C=C2)=CC=C1C(O)=O
CAS DataBase Reference :106685-40-9(CAS DataBase Reference)
Safety Information
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| Signal word: | Warning | ||||||||||||
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Description
Adapalene, a synthetic naphthoic acid derivative, is a selective agonist of retinoic acid receptor (RAR)-β and RAR-γ (Kds = 34 and 130 nM, respectively). At 0.1-10 μM, adapalene dose-dependently inhibits sebocyte growth, proliferation, and differentiation in a primary rat preputial cell culture system. Adapalene demonstrates anti-inflammatory and immunomodulatory activity by inhibiting 5-lipoxygenase-catalyzed leukotriene production and expression of toll-like receptor 2 on human monocytes. It is commonly used for the study of the pathogenesis and treatment of acne vulgaris.Related product price
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Suppliers and manufacturers
Changsha Junyu Chemexpress.co., Ltd
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
Beijing Cooperate Pharmaceutical Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
Shanghai Time Chemicals CO., Ltd.
Nanjing ChemLin Chemical Industry Co., Ltd.
