Apafant
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- $45 - $1732.5
- Product name: Apafant
- CAS: 105219-56-5
- MF: C22H22ClN5O2S
- MW: 455.96
- EINECS:
- MDL Number:MFCD00865271
- Synonyms:4-[3-[4-(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-1-oxopropyl]-morpholine;WEB 208;WEB 2086BS;4-[3-[4-(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-α][1,4]diazepin-2-yl]-1-oxopropyl]-morpholine;3-[4-(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-1-(4-morpholinyl)-1-propanone;4-(2-Chlorophenyl)-9-methyl-2-(3-morpholino-3-oxopropyl)-6H-thieno[3,2- f] [1,2,4]triazolo[4,3-a][1,4]diazepine;4-[3-[4[(2-CHLOROPHENYL)-9-METHYL-6H-THIENO[3,2-F][1,2,4]TRIAZOLO[4,3-A]DIAZEPIN-2-YL]-1-OXOPROPYL]]MORPHOLINE;WEB 2086
25 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biosynth
- Cayman Chemical
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 25mg
- 50mg
- 1
- 2mg
- 10
- 1mg
- 10mM*1mLinDMSO(Solution)
- 5mg
- 10MG
- 10mM*1mLinDMSO(Solid+Solvent)
- ManufacturerAK Scientific
- Product number1890BA
- Product descriptionApafant
- Packaging1mg
- Price$154
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0015803
- Product description4-[3-[4-(2-CHLOROPHENYL)-9-METHYL-6H-THIENO[3,2-F][1,2,4]TRIAZOLO[4,3-A][1,4]DIAZEPIN-2-YL]-1-OXOPROPYL]-MORPHOLINE 95.00%
- Packaging1MG
- Price$154.35
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0015803
- Product description4-[3-[4-(2-CHLOROPHENYL)-9-METHYL-6H-THIENO[3,2-F][1,2,4]TRIAZOLO[4,3-A][1,4]DIAZEPIN-2-YL]-1-OXOPROPYL]-MORPHOLINE 95.00%
- Packaging10MG
- Price$1732.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7024
- Product descriptionWEB2086
- Packaging5mg
- Price$378
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7024
- Product descriptionWEB 2086
- Packaging5mg
- Price$235
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-108634
- Product descriptionApafant 99.93%
- Packaging10mg
- Price$274
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-108634
- Product descriptionApafant 99.93%
- Packaging5mg
- Price$171
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-108634
- Product descriptionApafant 99.93%
- Packaging10mM*1mLinDMSO(Solution)
- Price$172
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-108634
- Product descriptionApafant 99.93%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$164
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-108634
- Product descriptionApafant 99.93%
- Packaging1mg
- Price$67
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-108634
- Product descriptionApafant 99.93%
- Packaging25mg
- Price$548
- Updated2026-05-26
- Buy
- ManufacturerBiosynth
- Product numberFA17951
- Product descriptionApafant
- Packaging50mg
- Price$612.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFA17951
- Product descriptionApafant
- Packaging10mg
- Price$400
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14532
- Product descriptionApafant ≥98%
- Packaging1mg
- Price$45
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number14532
- Product descriptionApafant ≥98%
- Packaging1mg
- Price$50
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14532
- Product descriptionApafant ≥98%
- Packaging5mg
- Price$169
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 1890BA | Apafant | 1mg | $154 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0015803 | 4-[3-[4-(2-CHLOROPHENYL)-9-METHYL-6H-THIENO[3,2-F][1,2,4]TRIAZOLO[4,3-A][1,4]DIAZEPIN-2-YL]-1-OXOPROPYL]-MORPHOLINE 95.00% | 1MG | $154.35 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0015803 | 4-[3-[4-(2-CHLOROPHENYL)-9-METHYL-6H-THIENO[3,2-F][1,2,4]TRIAZOLO[4,3-A][1,4]DIAZEPIN-2-YL]-1-OXOPROPYL]-MORPHOLINE 95.00% | 10MG | $1732.5 | 2021-12-16 | Buy |
| ApexBio Technology | B7024 | WEB2086 | 5mg | $378 | 2021-12-16 | Buy |
| ApexBio Technology | B7024 | WEB 2086 | 5mg | $235 | 2026-05-06 | Buy |
| Arctom | HY-108634 | Apafant 99.93% | 10mg | $274 | 2026-05-26 | Buy |
| Arctom | HY-108634 | Apafant 99.93% | 5mg | $171 | 2026-05-26 | Buy |
| Arctom | HY-108634 | Apafant 99.93% | 10mM*1mLinDMSO(Solution) | $172 | 2026-05-26 | Buy |
| Arctom | HY-108634 | Apafant 99.93% | 10mM*1mLinDMSO(Solid+Solvent) | $164 | 2026-05-26 | Buy |
| Arctom | HY-108634 | Apafant 99.93% | 1mg | $67 | 2026-05-26 | Buy |
| Arctom | HY-108634 | Apafant 99.93% | 25mg | $548 | 2026-05-26 | Buy |
| Biosynth | FA17951 | Apafant | 50mg | $612.5 | 2021-12-16 | Buy |
| Biosynth | FA17951 | Apafant | 10mg | $400 | 2021-12-16 | Buy |
| Cayman Chemical | 14532 | Apafant ≥98% | 1mg | $45 | 2026-04-30 | Buy |
| Cayman Chemical | 14532 | Apafant ≥98% | 1mg | $50 | 2024-03-01 | Buy |
| Cayman Chemical | 14532 | Apafant ≥98% | 5mg | $169 | 2026-04-30 | Buy |
Properties
Melting point :186-188°C
Boiling point :720.2±70.0 °C(Predicted)
Density :1.48
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL (clear solution)
pka :2.36±0.40(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChI :1S/C22H22ClN5O2S/c1-14-25-26-19-13-24-21(16-4-2-3-5-18(16)23)17-12-15(31-22(17)28(14)19)6-7-20(29)27-8-10-30-11-9-27/h2-5,12H,6-11,13H2,1H3
InChIKey :JGPJQFOROWSRRS-UHFFFAOYSA-N
SMILES :Cc1nnc2CN=C(c3ccccc3Cl)c4cc(CCC(=O)N5CCOCC5)sc4-n12
Boiling point :720.2±70.0 °C(Predicted)
Density :1.48
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL (clear solution)
pka :2.36±0.40(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChI :1S/C22H22ClN5O2S/c1-14-25-26-19-13-24-21(16-4-2-3-5-18(16)23)17-12-15(31-22(17)28(14)19)6-7-20(29)27-8-10-30-11-9-27/h2-5,12H,6-11,13H2,1H3
InChIKey :JGPJQFOROWSRRS-UHFFFAOYSA-N
SMILES :Cc1nnc2CN=C(c3ccccc3Cl)c4cc(CCC(=O)N5CCOCC5)sc4-n12
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Platelet-activating factor (PAF) is a biologically active phospholipid that activates platelets, polymorphonuclear leukocytes, monocytes, and macrophages. PAF also increases vascular permeability, decreases cardiac output, induces hypotension, stimulates uterine contraction, and has been implicated in pathological processes, such as inflammation and allergy. Apafant is a water soluble, selective PAF receptor antagonist that inhibits PAF binding to human PAF receptors with a Ki value of 9.9 nM. Apafant displays anti-inflammatory, antiangiogenic, and anticancer activity.More related product prices
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