Avasimibe
|
- $49 - $2250
- Product name: Avasimibe
- CAS: 166518-60-1
- MF: C29H43NO4S
- MW: 501.72
- EINECS:1592732-453-0
- MDL Number:MFCD00934956
- Synonyms:Avasimibe, >=98%;2,6-diisopropylphenyl 2-(2,4,6-triisopropylphenyl)acetylsulfamate;[[2,4,6-tris(1-methylethyl)phenyl]acetyl]-, 2,6-bis(1-methylethyl)phenyl ester] sulfamic acid;PD 148515;avasimibe;n-(2,6-dipropan-2-ylphenoxy)sulfonyl-2-(2,4,6-tripropan-2-ylphenyl)acetamide;N-[(2,6-DIISOPROPYLPHENOXY)SULFONYL]-2-(2,4,6-TRIISOPROPYLPHENYL)ACETAMIDE;((2,4,6-TRIS(1-METHYLETHYL)PHENYL)ACETYL)SULFAMICACID2,6-BIS(1-METHYLETHYL)PHENYLESTER
36 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 25
- 200mg
- 250mg
- 500MG
- 5
- 1g
- ManufacturerAK Scientific
- Product numberV2056
- Product descriptionavasimibe
- Packaging50mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA156472
- Product descriptionAvasimibe 95+%
- Packaging5mg
- Price$147
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA156472
- Product descriptionAvasimibe 95+%
- Packaging10mg
- Price$191
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA156472
- Product descriptionAvasimibe 95+%
- Packaging50mg
- Price$322
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA156472
- Product descriptionAvasimibe 95+%
- Packaging100mg
- Price$418
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA156472
- Product descriptionAvasimibe 95+%
- Packaging250mg
- Price$626
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA156472
- Product descriptionAvasimibe 95+%
- Packaging1g
- Price$2128
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000864
- Product descriptionAVASIMIBE 95.00%
- Packaging5MG
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000864
- Product descriptionAVASIMIBE 95.00%
- Packaging250MG
- Price$862.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000864
- Product descriptionAVASIMIBE 95.00%
- Packaging500MG
- Price$1325
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000864
- Product descriptionAVASIMIBE 95.00%
- Packaging1G
- Price$2250
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4318
- Product descriptionAvasimibe
- Packaging10mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0114
- Product descriptionAvasimibe
- Packaging5mg
- Price$109
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0114
- Product descriptionAvasimibe
- Packaging10mg
- Price$138
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0114
- Product descriptionAvasimibe
- Packaging50mg
- Price$334
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60441
- Product descriptionAvasimibe ≥98%
- Packaging10mg
- Price$118
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | V2056 | avasimibe | 50mg | $240 | 2021-12-16 | Buy |
| Ambeed | A156472 | Avasimibe 95+% | 5mg | $147 | 2021-12-16 | Buy |
| Ambeed | A156472 | Avasimibe 95+% | 10mg | $191 | 2021-12-16 | Buy |
| Ambeed | A156472 | Avasimibe 95+% | 50mg | $322 | 2021-12-16 | Buy |
| Ambeed | A156472 | Avasimibe 95+% | 100mg | $418 | 2021-12-16 | Buy |
| Ambeed | A156472 | Avasimibe 95+% | 250mg | $626 | 2021-12-16 | Buy |
| Ambeed | A156472 | Avasimibe 95+% | 1g | $2128 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000864 | AVASIMIBE 95.00% | 5MG | $450 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000864 | AVASIMIBE 95.00% | 250MG | $862.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000864 | AVASIMIBE 95.00% | 500MG | $1325 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000864 | AVASIMIBE 95.00% | 1G | $2250 | 2021-12-16 | Buy |
| ApexBio Technology | A4318 | Avasimibe | 10mg | $50 | 2021-12-16 | Buy |
| Apolloscientific | BISN0114 | Avasimibe | 5mg | $109 | 2021-12-16 | Buy |
| Apolloscientific | BISN0114 | Avasimibe | 10mg | $138 | 2021-12-16 | Buy |
| Apolloscientific | BISN0114 | Avasimibe | 50mg | $334 | 2021-12-16 | Buy |
| Arctom | CFN60441 | Avasimibe ≥98% | 10mg | $118 | 2021-12-16 | Buy |
Properties
Melting point :178-180° (Lee); mp 169.5-170.4° (Dozeman)
Density :1.072±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥40mg/mL
form :powder
pka :1.97±0.70(Predicted)
color :white to tan
InChIKey :PTQXTEKSNBVPQJ-UHFFFAOYSA-N
Density :1.072±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥40mg/mL
form :powder
pka :1.97±0.70(Predicted)
color :white to tan
InChIKey :PTQXTEKSNBVPQJ-UHFFFAOYSA-N
Safety Information
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Description
Acyl-Coenzyme A:cholesterol acyltransferases (ACAT1 and ACAT2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. Avasimibe is an orally bioavailable inhibitor of ACAT (IC50s = 24 and 9.2 μM for ACAT1 and ACAT2, respectively). It reduces foam cell formation in human macrophages in vitro, enhancing free cholesterol efflux and inhibiting the uptake of modified LDL and dose-dependently reduces plasma total triglyceride and VLDL cholesterol levels in cholesterol-fed animal models. Avasimibe inhibition of ACAT has been used to decrease amyloid β generation in models of Alzheimer’s disease.Related product price
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$13-950
