BFH772
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- $38 - $1339
- Product name: BFH772
- CAS: 890128-81-1
- MF: C23H16F3N3O3
- MW: 439.39
- EINECS:-0
- MDL Number:MFCD30534392
- Synonyms:BFH772;Bfh-722;CS-2412;BFH-772; BFH 772;1-Naphthalenecarboxamide, 6-[[6-(hydroxymethyl)-4-pyrimidinyl]oxy]-N-[3-(trifluoromethyl)phenyl]-;6-((6-(Hydroxymethyl)pyrimidin-4-yl)oxy)-N-(3-(trifluoromethyl)phenyl)-1-naphthamide;inhibit,BFH 772,VEGFR,BFH-772,BFH772,Vascular endothelial growth factor receptor,Inhibitor
30 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number1308DC
- Product descriptionCID24756034
- Packaging1mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1308DC
- Product descriptionCID24756034
- Packaging5mg
- Price$282
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA694724
- Product descriptionBFH772 98+%
- Packaging1mg
- Price$38
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA694724
- Product descriptionBFH772 98+%
- Packaging5mg
- Price$76
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA694724
- Product descriptionBFH772 98+%
- Packaging10mg
- Price$99
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA694724
- Product descriptionBFH772 98+%
- Packaging25mg
- Price$129
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA694724
- Product descriptionBFH772 98+%
- Packaging50mg
- Price$168
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA694724
- Product descriptionBFH772 98+%
- Packaging100mg
- Price$219
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA694724
- Product descriptionBFH772 98+%
- Packaging250mg
- Price$438
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA694724
- Product descriptionBFH772 98+%
- Packaging1g
- Price$1094
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6199
- Product descriptionBFH772
- Packaging1mg
- Price$79
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6199
- Product descriptionBFH772
- Packaging5mg
- Price$142
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6199
- Product descriptionBFH772
- Packaging10mg
- Price$236
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6199
- Product descriptionBFH772
- Packaging25mg
- Price$473
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6199
- Product descriptionBFH772
- Packaging50mg
- Price$709
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6199
- Product descriptionBFH772
- Packaging100mg
- Price$1339
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 1308DC | CID24756034 | 1mg | $140 | 2021-12-16 | Buy |
AK Scientific | 1308DC | CID24756034 | 5mg | $282 | 2021-12-16 | Buy |
Ambeed | A694724 | BFH772 98+% | 1mg | $38 | 2021-12-16 | Buy |
Ambeed | A694724 | BFH772 98+% | 5mg | $76 | 2021-12-16 | Buy |
Ambeed | A694724 | BFH772 98+% | 10mg | $99 | 2021-12-16 | Buy |
Ambeed | A694724 | BFH772 98+% | 25mg | $129 | 2021-12-16 | Buy |
Ambeed | A694724 | BFH772 98+% | 50mg | $168 | 2021-12-16 | Buy |
Ambeed | A694724 | BFH772 98+% | 100mg | $219 | 2021-12-16 | Buy |
Ambeed | A694724 | BFH772 98+% | 250mg | $438 | 2021-12-16 | Buy |
Ambeed | A694724 | BFH772 98+% | 1g | $1094 | 2021-12-16 | Buy |
ApexBio Technology | B6199 | BFH772 | 1mg | $79 | 2021-12-16 | Buy |
ApexBio Technology | B6199 | BFH772 | 5mg | $142 | 2021-12-16 | Buy |
ApexBio Technology | B6199 | BFH772 | 10mg | $236 | 2021-12-16 | Buy |
ApexBio Technology | B6199 | BFH772 | 25mg | $473 | 2021-12-16 | Buy |
ApexBio Technology | B6199 | BFH772 | 50mg | $709 | 2021-12-16 | Buy |
ApexBio Technology | B6199 | BFH772 | 100mg | $1339 | 2021-12-16 | Buy |
Properties
Boiling point :541.2±50.0 °C(Predicted)
Density :1.432±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :A crystalline solid
pka :12.65±0.70(Predicted)
Density :1.432±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :A crystalline solid
pka :12.65±0.70(Predicted)
Safety Information
Symbol(GHS): |
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Description
BFH772 is an inhibitor of VEGF receptor 2 (VEGFR2; IC50 = 0.0027 μM for the human receptor). It is selective for human VEGFR2 over mouse VEGFR2 and human VEGFR1 and VEGFR3 (IC50s = 1.5, 1.7, and 1.1 μM, respectively), as well as 40-fold selective over B-RAF, RET, and Tie2. BFH772 inhibits VEGF-induced proliferation of human umbilical vein endothelial cells (HUVECs; IC50 = <0.01 nM). It inhibits VEGF-induced increases in tissue weight and Tie2 levels in an angiogenesis chamber implant model in mice when administered at doses of 1 and 3 mg/kg per day. BFH772 (3 mg/kg per day) inhibits primary tumor and metastasis growth in a B16 melanoma mouse model.Suppliers and manufacturers
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