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ChemicalBook >> CAS DataBase List >> BFH772

BFH772

BFH772 price.
  • $38 - $1339
  • Product name: BFH772
  • CAS: 890128-81-1
  • MF: C23H16F3N3O3
  • MW: 439.39
  • EINECS:-0
  • MDL Number:MFCD30534392
  • Synonyms:BFH772;Bfh-722;CS-2412;BFH-772; BFH 772;1-Naphthalenecarboxamide, 6-[[6-(hydroxymethyl)-4-pyrimidinyl]oxy]-N-[3-(trifluoromethyl)phenyl]-;6-((6-(Hydroxymethyl)pyrimidin-4-yl)oxy)-N-(3-(trifluoromethyl)phenyl)-1-naphthamide;inhibit,BFH 772,VEGFR,BFH-772,BFH772,Vascular endothelial growth factor receptor,Inhibitor
30 prices
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  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
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  • ManufacturerAK Scientific
  • Product number1308DC
  • Product descriptionCID24756034
  • Packaging1mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1308DC
  • Product descriptionCID24756034
  • Packaging5mg
  • Price$282
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA694724
  • Product descriptionBFH772 98+%
  • Packaging1mg
  • Price$38
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA694724
  • Product descriptionBFH772 98+%
  • Packaging5mg
  • Price$76
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA694724
  • Product descriptionBFH772 98+%
  • Packaging10mg
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA694724
  • Product descriptionBFH772 98+%
  • Packaging25mg
  • Price$129
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA694724
  • Product descriptionBFH772 98+%
  • Packaging50mg
  • Price$168
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA694724
  • Product descriptionBFH772 98+%
  • Packaging100mg
  • Price$219
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA694724
  • Product descriptionBFH772 98+%
  • Packaging250mg
  • Price$438
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA694724
  • Product descriptionBFH772 98+%
  • Packaging1g
  • Price$1094
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6199
  • Product descriptionBFH772
  • Packaging1mg
  • Price$79
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6199
  • Product descriptionBFH772
  • Packaging5mg
  • Price$142
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6199
  • Product descriptionBFH772
  • Packaging10mg
  • Price$236
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6199
  • Product descriptionBFH772
  • Packaging25mg
  • Price$473
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6199
  • Product descriptionBFH772
  • Packaging50mg
  • Price$709
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6199
  • Product descriptionBFH772
  • Packaging100mg
  • Price$1339
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1308DC CID24756034 1mg $140 2021-12-16 Buy
AK Scientific 1308DC CID24756034 5mg $282 2021-12-16 Buy
Ambeed A694724 BFH772 98+% 1mg $38 2021-12-16 Buy
Ambeed A694724 BFH772 98+% 5mg $76 2021-12-16 Buy
Ambeed A694724 BFH772 98+% 10mg $99 2021-12-16 Buy
Ambeed A694724 BFH772 98+% 25mg $129 2021-12-16 Buy
Ambeed A694724 BFH772 98+% 50mg $168 2021-12-16 Buy
Ambeed A694724 BFH772 98+% 100mg $219 2021-12-16 Buy
Ambeed A694724 BFH772 98+% 250mg $438 2021-12-16 Buy
Ambeed A694724 BFH772 98+% 1g $1094 2021-12-16 Buy
ApexBio Technology B6199 BFH772 1mg $79 2021-12-16 Buy
ApexBio Technology B6199 BFH772 5mg $142 2021-12-16 Buy
ApexBio Technology B6199 BFH772 10mg $236 2021-12-16 Buy
ApexBio Technology B6199 BFH772 25mg $473 2021-12-16 Buy
ApexBio Technology B6199 BFH772 50mg $709 2021-12-16 Buy
ApexBio Technology B6199 BFH772 100mg $1339 2021-12-16 Buy

Properties

Boiling point :541.2±50.0 °C(Predicted)
Density :1.432±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :A crystalline solid
pka :12.65±0.70(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

BFH772 is an inhibitor of VEGF receptor 2 (VEGFR2; IC50 = 0.0027 μM for the human receptor). It is selective for human VEGFR2 over mouse VEGFR2 and human VEGFR1 and VEGFR3 (IC50s = 1.5, 1.7, and 1.1 μM, respectively), as well as 40-fold selective over B-RAF, RET, and Tie2. BFH772 inhibits VEGF-induced proliferation of human umbilical vein endothelial cells (HUVECs; IC50 = <0.01 nM). It inhibits VEGF-induced increases in tissue weight and Tie2 levels in an angiogenesis chamber implant model in mice when administered at doses of 1 and 3 mg/kg per day. BFH772 (3 mg/kg per day) inhibits primary tumor and metastasis growth in a B16 melanoma mouse model.