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ChemicalBook >> CAS DataBase List >> BI-6C9

BI-6C9

BI-6C9 price.
  • $55 - $2455.5
  • Product name: BI-6C9
  • CAS: 791835-21-7
  • MF: C23H25N3O4S2
  • MW: 471.59
  • EINECS:
  • MDL Number:MFCD07784498
  • Synonyms:N-[4-(4-aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide;Butanamide, N-[4-[(4-aminophenyl)thio]phenyl]-4-[[(4-methoxyphenyl)sulfonyl]amino]-;N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide;Inhibitor,fission,Neurodegeneration,Bid,BI6C9,BI 6C9,Mitochodondrial,death,Mitochondria,Apoptosis,inhibit,Glutamate,stress,Neuronal,Bcl-2,Mitochondrial,Mitochondrial Metabolism,potential,cell,Oxidative,membrane,BI-6C9,BI-6C-9;BI-6C9, 10 mM in DMSO
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  • aablocks
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  • Cayman Chemical
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  • Manufactureraablocks
  • Product numberAA005340
  • Product descriptionN-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97%
  • Packaging1mg
  • Price$59
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA005340
  • Product descriptionN-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97
  • Packaging2mg
  • Price$90
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA005340
  • Product descriptionN-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97
  • Packaging5mg
  • Price$138
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA005340
  • Product descriptionN-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97
  • Packaging10mg
  • Price$198
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA005340
  • Product descriptionN-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97
  • Packaging25mg
  • Price$337
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA005340
  • Product descriptionN-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97
  • Packaging50mg
  • Price$490
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA005340
  • Product descriptionN-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97
  • Packaging100mg
  • Price$679
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA005340
  • Product descriptionN-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97
  • Packaging200mg
  • Price$892
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberY230417
  • Product descriptionBI-6C9 98%
  • Packaging100MG
  • Price$945
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberY230417
  • Product descriptionBI-6C9 98%
  • Packaging25MG
  • Price$505
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberY230417
  • Product descriptionBI-6C9 98%
  • Packaging5MG
  • Price$170
  • Updated2026-05-27
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  • ManufacturerAK Scientific
  • Product number8956CS
  • Product descriptionN-[4-(4-Aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide
  • Packaging1mg
  • Price$159
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product number8956CS
  • Product descriptionN-[4-(4-Aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide
  • Packaging5mg
  • Price$367
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA1173077
  • Product descriptionBI-6C9 97%
  • Packaging50mg
  • Price$753
  • Updated2026-06-05
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  • ManufacturerAmbeed
  • Product numberA1173077
  • Product descriptionBI-6C9 97%
  • Packaging25mg
  • Price$536
  • Updated2026-06-05
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  • ManufacturerAmbeed
  • Product numberA1173077
  • Product descriptionBI-6C9 97%
  • Packaging1mg
  • Price$74
  • Updated2026-06-05
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Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA005340 N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97% 1mg $59 2026-05-28 Buy
aablocks AA005340 N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97 2mg $90 2026-05-28 Buy
aablocks AA005340 N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97 5mg $138 2026-05-28 Buy
aablocks AA005340 N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97 10mg $198 2026-05-28 Buy
aablocks AA005340 N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97 25mg $337 2026-05-28 Buy
aablocks AA005340 N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97 50mg $490 2026-05-28 Buy
aablocks AA005340 N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97 100mg $679 2026-05-28 Buy
aablocks AA005340 N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97 200mg $892 2026-05-28 Buy
ACHEMBLOCK Y230417 BI-6C9 98% 100MG $945 2026-05-27 Buy
ACHEMBLOCK Y230417 BI-6C9 98% 25MG $505 2026-05-27 Buy
ACHEMBLOCK Y230417 BI-6C9 98% 5MG $170 2026-05-27 Buy
AK Scientific 8956CS N-[4-(4-Aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide 1mg $159 2021-12-16 Buy
AK Scientific 8956CS N-[4-(4-Aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide 5mg $367 2021-12-16 Buy
Ambeed A1173077 BI-6C9 97% 50mg $753 2026-06-05 Buy
Ambeed A1173077 BI-6C9 97% 25mg $536 2026-06-05 Buy
Ambeed A1173077 BI-6C9 97% 1mg $74 2026-06-05 Buy

Properties

Density :1.36±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: 24 mg/mL, soluble
form :solid
pka :11.58±0.50(Predicted)
color :off-white
InChI :1S/C23H25N3O4S2/c1-30-19-8-14-22(15-9-19)32(28,29)25-16-2-3-23(27)26-18-6-12-21(13-7-18)31-20-10-4-17(24)5-11-20/h4-15,25H,2-3,16,24H2,1H3,(H,26,27)
InChIKey :LCFUJBSKPDPGKO-UHFFFAOYSA-N
SMILES :COc1ccc(cc1)S(=O)(=O)NCCCC(=O)Nc2ccc(Sc3ccc(N)cc3)cc2

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

BH3-interacting domain (Bid) is cleaved by caspase-8 to produce the truncated protein tBid, which facilitates cytochrome c release from mitochondria and drives apoptosis. BI-6C9 is an inhibitor of tBid (Kd = 20 μM), blocking the release of both cytochrome c and second mitochondria-derived activator of caspase from mitochondria. It prevents apoptosis in neurons treated with glutamate or oxygen-glucose deprivation. BI-6C9 (10 μM) also inhibits the nuclear translocation of apoptosis-inducing factor AIF, preventing the death of ovarian OVCAR-3 cancer cells induced by IFN-α2a.

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