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ChemicalBook >> CAS DataBase List >> Bivalirudin

Bivalirudin

Bivalirudin price.
  • $55 - $2425.5
  • Product name: Bivalirudin
  • CAS: 128270-60-0
  • MF: C98H138N24O33
  • MW: 2180.29
  • EINECS:274-570-6
  • MDL Number:MFCD08282793
  • Synonyms:Bivalirudin, TFA;BIVALIRUDIN;BITTERMELONP.E;Human Bivalirudin;DPHE-PRO-ARG-PRO-GLY-GLY-GLY-GLY-ASN-GLY-ASP-PHE-GLU-GLU-LLE-PRO-GLU-GLU-TYR-LEU;Bivalirudin BG 8967, Hirulog, Hirulog I;BG 8967, Hirulog, Hirulog I;H-D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH
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  • American Custom Chemicals Corporation
  • ApexBio Technology
  • AvaChem
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
Package
  • 001
  • 5mg
  • 25mg
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  • 003
  • 10mg
  • 100mg
  • 002
  • 250MG
  • 500mg
  • 1G
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPEP0000826
  • Product descriptionBIVALIRUDIN ACETATE 95.00%
  • Packaging250MG
  • Price$1752.43
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPEP0000826
  • Product descriptionBIVALIRUDIN ACETATE 95.00%
  • Packaging1G
  • Price$2425.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3244
  • Product descriptionBivalirudinTrifluoroacetate
  • Packaging100mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3244
  • Product descriptionBivalirudinTrifluoroacetate
  • Packaging500mg
  • Price$378
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number2233
  • Product descriptionBivalirudin
  • Packaging50mg
  • Price$190
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number2233
  • Product descriptionBivalirudin
  • Packaging250mg
  • Price$290
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFB29604
  • Product descriptionBivalirudin
  • Packaging10mg
  • Price$55
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFB29604
  • Product descriptionBivalirudin
  • Packaging50mg
  • Price$194
  • Updated2021-12-16
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  • ManufacturerCayman Chemical
  • Product number23035
  • Product descriptionBivalirudin ≥98%
  • Packaging5mg
  • Price$62
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number23035
  • Product descriptionBivalirudin ≥98%
  • Packaging10mg
  • Price$92
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number23035
  • Product descriptionBivalirudin ≥98%
  • Packaging25mg
  • Price$211
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number23035
  • Product descriptionBivalirudin ≥98%
  • Packaging50mg
  • Price$357
  • Updated2024-03-01
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  • ManufacturerChem-Impex
  • Product number33031
  • Product descriptionBivalirudin trifluoroacetate salt
  • Packaging250MG
  • Price$498.53
  • Updated2021-12-16
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  • ManufacturerCrysdot
  • Product numberCD31004002
  • Product descriptionBivalirudinTrifluoroacetate 98+%
  • Packaging100mg
  • Price$143
  • Updated2021-12-16
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  • ManufacturerDC Chemicals
  • Product number013183
  • Product descriptionBivalirudin
  • Packaging001
  • Price$650
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product number013183
  • Product descriptionBivalirudin
  • Packaging002
  • Price$1000
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation PEP0000826 BIVALIRUDIN ACETATE 95.00% 250MG $1752.43 2021-12-16 Buy
American Custom Chemicals Corporation PEP0000826 BIVALIRUDIN ACETATE 95.00% 1G $2425.5 2021-12-16 Buy
ApexBio Technology A3244 BivalirudinTrifluoroacetate 100mg $125 2021-12-16 Buy
ApexBio Technology A3244 BivalirudinTrifluoroacetate 500mg $378 2021-12-16 Buy
AvaChem 2233 Bivalirudin 50mg $190 2021-12-16 Buy
AvaChem 2233 Bivalirudin 250mg $290 2021-12-16 Buy
Biosynth Carbosynth FB29604 Bivalirudin 10mg $55 2021-12-16 Buy
Biosynth Carbosynth FB29604 Bivalirudin 50mg $194 2021-12-16 Buy
Cayman Chemical 23035 Bivalirudin ≥98% 5mg $62 2024-03-01 Buy
Cayman Chemical 23035 Bivalirudin ≥98% 10mg $92 2024-03-01 Buy
Cayman Chemical 23035 Bivalirudin ≥98% 25mg $211 2024-03-01 Buy
Cayman Chemical 23035 Bivalirudin ≥98% 50mg $357 2024-03-01 Buy
Chem-Impex 33031 Bivalirudin trifluoroacetate salt 250MG $498.53 2021-12-16 Buy
Crysdot CD31004002 BivalirudinTrifluoroacetate 98+% 100mg $143 2021-12-16 Buy
DC Chemicals 013183 Bivalirudin 001 $650 2021-12-16 Buy
DC Chemicals 013183 Bivalirudin 002 $1000 2021-12-16 Buy

Properties

Density :1.52±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :≥54.5 mg/mL in DMSO with gentle warming; ≥10.18 mg/mL in EtOH with gentle warming and ultrasonic; ≥43.5 mg/mL in H2O with gentle warming
form :powder
color :white to off-white
Sequence :D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH
InChIKey :OIRCOABEOLEUMC-GEJPAHFPSA-N

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Bivalirudin was launched in New Zealand as an anticoagulant for i.v. treatment of patients with unstable angina undergoing percutaneous transluminal coronary angioplasty. Bivalirubin is a synthetic 20 amino acid peptide rationally modeled on hirudin (residues 53- 64), the most potent and specific naturally-occuring known inhibitor of thrombin, the enzyme that plays a key role in hemostasis and blood clot formation. This peptide is a direct thrombin inhibitor that maintains the unique bivalent binding properties of hirudin to the catalytic site and to the fibrin-recognition exosite of the enzyme, so acting directly on thrombin with high affinity and specificity. In vitro studies demonstrated that alpha- and zeta-thrombins, both with the higher fibrinogen-procoagulant activities, were inhibited. In rats receiving high doses of bivalirudin, the platelet deposition in carotide was reduced by 63% compared to controls. The results of clinical studies, conducted only in patients receiving concomitant aspirin, suggested that the use of bivalirudin was more efficacious and more predictable than unfractionated heparin, with fewer bleeding complications. Despite some unresolved developmental issues, the attractive properties of this novel agent could make it a useful alternative to heparin in a variety of coagulation disorders.

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