CAY10603
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- $48 - $2970
- Product name: CAY10603
- CAS: 1045792-66-2
- MF: C22H30N4O6
- MW: 446.5
- EINECS:
- MDL Number:MFCD17010286
- Synonyms:N-[4-[3-[[[7-(Hydroxyamino)-7-oxoheptyl]amino]carbonyl]-5-isoxazolyl]phenyl]carbamic acid 1,1-dimethylethyl ester;HDAC6 inhibitor ISOX;CAY10603;Isox;tert-butyl 4-(3-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)isoxazol-5-yl)phenylcarbamate;HDAC6 Inhibitor;Histone Deacetylase Inhibitor VIII - CAS 1045792-66-2 - Calbiochem;CAY10603; CAY-10603; CAY 10603.
42 prices
Selected condition：
Brand
- ACHEMBLOCK
- ApexBio Technology
- Axon Medchem
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 1mg
- 5mg
- 10mg
- 500μg
- 1000μg
- 10mM*1mLinDMSO
- 10mM(in1mLDMSO)
- 25MG
- 50mg
- 100MG
- 250mg
- 1G
- 1 unit
- 10mM(in 1mL DMSO)
- 1 mg
- ManufacturerACHEMBLOCK
- Product numberT101397
- Product descriptiontert-butyl (4-(3-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)isoxazol-5-yl)phenyl)carbamate 98%
- Packaging25MG
- Price$170
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberT101397
- Product descriptiontert-butyl (4-(3-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)isoxazol-5-yl)phenyl)carbamate 98%
- Packaging100MG
- Price$495
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberT101397
- Product descriptiontert-butyl (4-(3-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)isoxazol-5-yl)phenyl)carbamate 98%
- Packaging1G
- Price$2970
- Updated2026-05-25
- Buy
- ManufacturerApexBio Technology
- Product numberB4856
- Product descriptionCAY10603
- Packaging25mg
- Price$340
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4856
- Product descriptionCAY10603
- Packaging25mg
- Price$374
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB4856
- Product descriptionCAY10603
- Packaging1mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4856
- Product descriptionCAY10603
- Packaging1mg
- Price$66
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB4856
- Product descriptionCAY10603
- Packaging5mg
- Price$105
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4856
- Product descriptionCAY10603
- Packaging5mg
- Price$116
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB4856
- Product descriptionCAY10603
- Packaging10mM(in 1mL DMSO)
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4856
- Product descriptionCAY10603
- Packaging10mM(in1mLDMSO)
- Price$121
- Updated2026-05-06
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1645
- Product descriptionHDAC6 inhibitor ISOX
- Packaging5mg
- Price$121
- Updated2026-05-19
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1645
- Product descriptionHDAC6inhibitorISOX 99%
- Packaging25mg
- Price$346.5
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1645
- Product descriptionHDAC6 inhibitor ISOX
- Packaging25mg
- Price$363
- Updated2026-05-19
- Buy
- ManufacturerBiosynth
- Product numberFH138524
- Product descriptionHistone deacetylase inhibitor VIII
- Packaging10mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFH138524
- Product descriptionHistone deacetylase inhibitor VIII
- Packaging50mg
- Price$438
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | T101397 | tert-butyl (4-(3-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)isoxazol-5-yl)phenyl)carbamate 98% | 25MG | $170 | 2026-05-25 | Buy |
| ACHEMBLOCK | T101397 | tert-butyl (4-(3-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)isoxazol-5-yl)phenyl)carbamate 98% | 100MG | $495 | 2026-05-25 | Buy |
| ACHEMBLOCK | T101397 | tert-butyl (4-(3-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)isoxazol-5-yl)phenyl)carbamate 98% | 1G | $2970 | 2026-05-25 | Buy |
| ApexBio Technology | B4856 | CAY10603 | 25mg | $340 | 2021-12-16 | Buy |
| ApexBio Technology | B4856 | CAY10603 | 25mg | $374 | 2026-05-06 | Buy |
| ApexBio Technology | B4856 | CAY10603 | 1mg | $60 | 2021-12-16 | Buy |
| ApexBio Technology | B4856 | CAY10603 | 1mg | $66 | 2026-05-06 | Buy |
| ApexBio Technology | B4856 | CAY10603 | 5mg | $105 | 2021-12-16 | Buy |
| ApexBio Technology | B4856 | CAY10603 | 5mg | $116 | 2026-05-06 | Buy |
| ApexBio Technology | B4856 | CAY10603 | 10mM(in 1mL DMSO) | $120 | 2021-12-16 | Buy |
| ApexBio Technology | B4856 | CAY10603 | 10mM(in1mLDMSO) | $121 | 2026-05-06 | Buy |
| Axon Medchem | Axon1645 | HDAC6 inhibitor ISOX | 5mg | $121 | 2026-05-19 | Buy |
| Axon Medchem | Axon1645 | HDAC6inhibitorISOX 99% | 25mg | $346.5 | 2021-12-16 | Buy |
| Axon Medchem | Axon1645 | HDAC6 inhibitor ISOX | 25mg | $363 | 2026-05-19 | Buy |
| Biosynth | FH138524 | Histone deacetylase inhibitor VIII | 10mg | $125 | 2021-12-16 | Buy |
| Biosynth | FH138524 | Histone deacetylase inhibitor VIII | 50mg | $438 | 2021-12-16 | Buy |
Properties
Density :1.231±0.06 g/cm3(Predicted)
storage temp. :+2C to +8C
solubility :≥22.35 mg/mL in DMSO; insoluble in EtOH; ≥24.85 mg/mL in H2O
form :Beige to light brown solid
pka :9.47±0.20(Predicted)
color :White to light yellow
InChIKey :WWGBHDIHIVGYLZ-UHFFFAOYSA-N
SMILES :N(O)C(=O)CCCCCCNC(=O)c1n[o]c(c1)c2ccc(cc2)NC(=O)OC(C)(C)C
storage temp. :+2C to +8C
solubility :≥22.35 mg/mL in DMSO; insoluble in EtOH; ≥24.85 mg/mL in H2O
form :Beige to light brown solid
pka :9.47±0.20(Predicted)
color :White to light yellow
InChIKey :WWGBHDIHIVGYLZ-UHFFFAOYSA-N
SMILES :N(O)C(=O)CCCCCCNC(=O)c1n[o]c(c1)c2ccc(cc2)NC(=O)OC(C)(C)C
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
Histone deacetylase 6 (HDAC6) is a class II HDAC that represses transcription by removing acetyl groups from histones. In addition, HDAC6 deacetylases tubulin, which is important in regulating microtubule stability and function. CAY10603 is a potent and selective inhibitor of HDAC6 (IC50 = 0.002 nM, as compared with 271, 252, 0.42, 6851, and 90.7 nM for HDAC1, 2, 3, 8, and 10, respectively). Also, CAY10603 prevents the growth of several pancreatic cancer cell lines (IC50 = 0.1-1 μM). The HDAC6 inhibitor is more active in inhibiting cell growth than the broad spectrum HDAC inhibitor suberoylanilide hydroxamic acid (SAHA).Related product price
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