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ChemicalBook >> CAS DataBase List >> Soluble Epoxide Hydrolase Inhibitor Screening Assay Kit

Soluble Epoxide Hydrolase Inhibitor Screening Assay Kit

Soluble Epoxide Hydrolase Inhibitor Screening Assay Kit price.
2 prices
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Brand
  • Cayman Chemical
Package
  • 96Well
  • ManufacturerCayman Chemical
  • Product number10011671
  • Product descriptionSoluble Epoxide Hydrolase Inhibitor Screening Assay Kit
  • Packaging96Well
  • Price$244
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10011671
  • Product descriptionSoluble Epoxide Hydrolase Inhibitor Screening Assay Kit
  • Packaging96Well
  • Price$303
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 10011671 Soluble Epoxide Hydrolase Inhibitor Screening Assay Kit 96Well $244 2024-03-01 Buy
Cayman Chemical 10011671 Soluble Epoxide Hydrolase Inhibitor Screening Assay Kit 96Well $303 2026-04-30 Buy

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Description

Soluble epoxide hydrolase (sEH) catalyzes the hydrolysis of exogenous and endogenous epoxides to vicinal diols. Endogenous substrates for sEH include epoxyeicosatrienoic acids (EETs) which exhibit vasodialatory and anti-inflammatory activity. Small molecule inhibitors of sEH may therefore hold promise as therapeutics for the treatment of hypertension and vascular inflammation. Cayman’s fluorescence-based sEH Inhibitor Screening Assay Kit provides a convenient method for screening epoxide hydrolase inhibitors. The assay utilizes (3-phenyl-oxiranyl)-acetic acid cyano-(6-methoxy-naphthalen-2-yl)-methyl ester (PHOME) as a substrate. Hydrolysis of PHOME by epoxide hydrolase produces the highly fluorescent 6-methoxy-2-naphthaldehyde which can be analyzed using an excitation wavelength of 330 nm and emission wavelength of 465 nm. Each kit contains buffer, substrate, and sufficient human recombinant sEH for 100 tests.Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.WARNING This product is not for human or veterinary use.

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