AS-605240 (potassium salt)
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- $36 - $587
- Product name: AS-605240 (potassium salt)
- CAS:
- MF: C12H6KN3O2S
- MW: 295.35824
- EINECS:
- MDL Number:
- Synonyms:AS-605240 (potassium salt)
4 prices
Selected condition:
Brand
- Cayman Chemical
Package
- 1mg
- 5mg
- 10mg
- 25mg
- ManufacturerCayman Chemical
- Product number9000980
- Product descriptionAS-605240 (potassium salt) ≥98%
- Packaging1mg
- Price$36
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number9000980
- Product descriptionAS-605240 (potassium salt) ≥98%
- Packaging5mg
- Price$153
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number9000980
- Product descriptionAS-605240 (potassium salt) ≥98%
- Packaging10mg
- Price$268
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number9000980
- Product descriptionAS-605240 (potassium salt) ≥98%
- Packaging25mg
- Price$587
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Cayman Chemical | 9000980 | AS-605240 (potassium salt) ≥98% | 1mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 9000980 | AS-605240 (potassium salt) ≥98% | 5mg | $153 | 2026-04-30 | Buy |
| Cayman Chemical | 9000980 | AS-605240 (potassium salt) ≥98% | 10mg | $268 | 2026-04-30 | Buy |
| Cayman Chemical | 9000980 | AS-605240 (potassium salt) ≥98% | 25mg | $587 | 2026-04-30 | Buy |
Properties
solubility :DMF: 3 mg/ml
DMSO: 5 mg/ml
DMSO: PBS (pH 7.2) (1:10): 0.1 mg/ml
DMSO: 5 mg/ml
DMSO: PBS (pH 7.2) (1:10): 0.1 mg/ml
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
AS-605240 is an orally active inhibitor of PI3-kinase γ that suppresses joint inflammation in mouse models of rheumatoid arthritis.1 It inhibits human recombinant PI3Kγ, α, β, and δ in an ATP-competitive manner with IC50 values of 8, 60, 270, and 300 nM, respectively.1 AS-605240 inhibits C5a-mediated phosphorylation of protein kinase B in RAW 264 cells with an IC50 value of 90 nM. In vivo, AS-605240 reduced RANTES-induced peritoneal neutrophil recruitment in a mouse model of leukocyte chemotaxis with an ED50 value of 9.1 mg/kg. AS-605240 (potassium salt) has improved solubility compared to AS-605240 (Item No. 10007707).WARNING This product is not for human or veterinary use.Related product price
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