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ChemicalBook >> CAS DataBase List >> PAD1 Inhibitor Screening Assay Kit (AMC)

PAD1 Inhibitor Screening Assay Kit (AMC)

PAD1 Inhibitor Screening Assay Kit (AMC) price.
2 prices
Selected condition:
Brand
  • Cayman Chemical
Package
  • 96Well
  • ManufacturerCayman Chemical
  • Product number701440
  • Product descriptionPAD1 Inhibitor Screening Assay Kit (AMC)
  • Packaging96Well
  • Price$493
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number701440
  • Product descriptionPAD1 Inhibitor Screening Assay Kit (AMC)
  • Packaging96Well
  • Price$543
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 701440 PAD1 Inhibitor Screening Assay Kit (AMC) 96Well $493 2024-03-01 Buy
Cayman Chemical 701440 PAD1 Inhibitor Screening Assay Kit (AMC) 96Well $543 2026-04-30 Buy

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Description

Cayman’s PAD1 Inhibitor Screening Assay Kit (AMC) provides a convenient method for screening human PAD1 inhibitors. This assay utilizes a fluorescent substrate (Z-Arg-AMC) consisting of an arginine residue, a carboxybenzyl group, and a fluorophore (7-amino-4-methylcoumarin, AMC).1 Acylation of AMC onto the arginine residue masks the fluorescence of the fluorophore. In the absence of PAD1, the substrate remains unaltered, allowing the developer to release free AMC. In the presence of PAD1, the arginine of the substrate is citrullinated, and while the reaction is quenched by the addition of developer, free AMC is not released. Fluorescence is analyzed with an excitation wavelength of 355-365 nm and an emission wavelength of 445-455 nm. The fluorescent signal is inversely proportional to the amount of citrullination by PAD1.Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.WARNING This product is not for human or veterinary use.

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