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ChemicalBook >> CAS DataBase List >> Onatasertib (CC-223)

Onatasertib (CC-223)

Onatasertib (CC-223) price.
  • $21 - $1900
  • Product name: Onatasertib (CC-223)
  • CAS: 1228013-30-6
  • MF: C21H27N5O3
  • MW: 397.47
  • EINECS:
  • MDL Number:MFCD28976054
  • Synonyms:7-[6-(2-Hydroxypropan-2-yl)pyridin-3-yl]-1-(trans-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one;Pyrazino[2,3-b]pyrazin-2(1H)-one, 3,4-dihydro-7-[6-(1-hydroxy-1-methylethyl)-3-pyridinyl]-1-(trans-4-methoxycyclohexyl)-;7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((1r,4r)-4-methoxycyclohexyl)-3,4-dihydropyrazino-[2,3-b]pyrazin-2(1H)-one;CS-2163;CS-2039;CC223;CC 223; 7-[6-(2-Hydroxy-2-propanyl)-3-pyridinyl]-1-(trans-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one;Onatasertib(CC 223,ATG-008)
Price49 Properties Safety Information Description
49 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
Package
  • 10mM*1mLinDMSO(Solution)
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 10mM*1mLinDMSO
  • 25mg
  • 50mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 100mg
  • 250MG
  • 1G
  • Manufactureraablocks
  • Product numberAA000JF6
  • Product description7-(6-(2-Hydroxypropan-2-Yl)Pyridin-3-Yl)-1-(Trans-4-Methoxycyclohexyl)-3,4-Dihydropyrazino[2,3-B]Pyrazin-2(1H)-One 99%
  • Packaging2mg
  • Price$21
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000JF6
  • Product description7-(6-(2-Hydroxypropan-2-Yl)Pyridin-3-Yl)-1-(Trans-4-Methoxycyclohexyl)-3,4-Dihydropyrazino[2,3-B]Pyrazin-2(1H)-One 99%
  • Packaging5mg
  • Price$31
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000JF6
  • Product description7-(6-(2-Hydroxypropan-2-Yl)Pyridin-3-Yl)-1-(Trans-4-Methoxycyclohexyl)-3,4-Dihydropyrazino[2,3-B]Pyrazin-2(1H)-One 99%
  • Packaging10mg
  • Price$49
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000JF6
  • Product description7-(6-(2-Hydroxypropan-2-Yl)Pyridin-3-Yl)-1-(Trans-4-Methoxycyclohexyl)-3,4-Dihydropyrazino[2,3-B]Pyrazin-2(1H)-One 99%
  • Packaging25mg
  • Price$97
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000JF6
  • Product description7-(6-(2-Hydroxypropan-2-Yl)Pyridin-3-Yl)-1-(Trans-4-Methoxycyclohexyl)-3,4-Dihydropyrazino[2,3-B]Pyrazin-2(1H)-One ≥99%
  • Packaging50mg
  • Price$189
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000JF6
  • Product description7-(6-(2-Hydroxypropan-2-Yl)Pyridin-3-Yl)-1-(Trans-4-Methoxycyclohexyl)-3,4-Dihydropyrazino[2,3-B]Pyrazin-2(1H)-One ≥99%
  • Packaging100mg
  • Price$341
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberH-8937
  • Product descriptionCC-223 98%
  • Packaging250MG
  • Price$435
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberH-8937
  • Product descriptionCC-223 98%
  • Packaging1G
  • Price$1125
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number9870DN
  • Product descriptionCc-223
  • Packaging10mg
  • Price$442
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number9870DN
  • Product descriptionCc-223
  • Packaging5mg
  • Price$297
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0002487
  • Product descriptionCC-223 95.00%
  • Packaging5MG
  • Price$500.96
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6171
  • Product descriptionCC-223
  • Packaging25mg
  • Price$313
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6171
  • Product descriptionCC-223
  • Packaging25mg
  • Price$313
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6171
  • Product descriptionCC-223
  • Packaging5mg
  • Price$103
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6171
  • Product descriptionCC-223
  • Packaging5mg
  • Price$103
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberHY-16956
  • Product descriptionOnatasertib 98.15%
  • Packaging5mg
  • Price$95
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA000JF6 7-(6-(2-Hydroxypropan-2-Yl)Pyridin-3-Yl)-1-(Trans-4-Methoxycyclohexyl)-3,4-Dihydropyrazino[2,3-B]Pyrazin-2(1H)-One 99% 2mg $21 2026-05-25 Buy
aablocks AA000JF6 7-(6-(2-Hydroxypropan-2-Yl)Pyridin-3-Yl)-1-(Trans-4-Methoxycyclohexyl)-3,4-Dihydropyrazino[2,3-B]Pyrazin-2(1H)-One 99% 5mg $31 2026-05-25 Buy
aablocks AA000JF6 7-(6-(2-Hydroxypropan-2-Yl)Pyridin-3-Yl)-1-(Trans-4-Methoxycyclohexyl)-3,4-Dihydropyrazino[2,3-B]Pyrazin-2(1H)-One 99% 10mg $49 2026-05-25 Buy
aablocks AA000JF6 7-(6-(2-Hydroxypropan-2-Yl)Pyridin-3-Yl)-1-(Trans-4-Methoxycyclohexyl)-3,4-Dihydropyrazino[2,3-B]Pyrazin-2(1H)-One 99% 25mg $97 2026-05-25 Buy
aablocks AA000JF6 7-(6-(2-Hydroxypropan-2-Yl)Pyridin-3-Yl)-1-(Trans-4-Methoxycyclohexyl)-3,4-Dihydropyrazino[2,3-B]Pyrazin-2(1H)-One ≥99% 50mg $189 2026-05-25 Buy
aablocks AA000JF6 7-(6-(2-Hydroxypropan-2-Yl)Pyridin-3-Yl)-1-(Trans-4-Methoxycyclohexyl)-3,4-Dihydropyrazino[2,3-B]Pyrazin-2(1H)-One ≥99% 100mg $341 2026-05-25 Buy
ACHEMBLOCK H-8937 CC-223 98% 250MG $435 2026-05-27 Buy
ACHEMBLOCK H-8937 CC-223 98% 1G $1125 2026-05-27 Buy
AK Scientific 9870DN Cc-223 10mg $442 2021-12-16 Buy
AK Scientific 9870DN Cc-223 5mg $297 2021-12-16 Buy
American Custom Chemicals Corporation KIN0002487 CC-223 95.00% 5MG $500.96 2021-12-16 Buy
ApexBio Technology B6171 CC-223 25mg $313 2021-12-16 Buy
ApexBio Technology B6171 CC-223 25mg $313 2026-05-06 Buy
ApexBio Technology B6171 CC-223 5mg $103 2026-05-06 Buy
ApexBio Technology B6171 CC-223 5mg $103 2021-12-16 Buy
Arctom HY-16956 Onatasertib 98.15% 5mg $95 2026-05-26 Buy
Next Last

Properties

Boiling point :562.9±60.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥108 mg/mL in DMSO; ≥20.28 mg/mL in EtOH
form :crystalline solid
pka :13+-.0.29(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

CC-223 is a potent, selective, and orally bioavailable inhibitor of mTOR kinase, demonstrating inhibition of mTORC1 (pS6RP and p4EBP1) and mTORC2 [pAKT(S473)] in cellular systems. After tumor-bearing mice was treated with CC-223 for a single oral dose. It exhibited dose-dependent tumor growth inhibition in multiple solid tumor xenografts. The observed antitumor activity of CC-223 is likely to be mediated through inhibition of both mTORC1 and mTORC2. CC-223 is currently in phase I clinical trials for its treatment of advanced solid and hematologic cancers. 

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Suppliers and manufacturers

career henan chemical co
7-[6-(2-Hydroxy-2-propanyl)-3-pyridinyl]-1-(trans-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one
$1.00
7-[6-(2-Hydroxy-2-propanyl)-3-pyridinyl]-1-(trans-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one CAS:1228013-30-6
TargetMol Chemicals Inc.
Onatasertib
$35.00
Onatasertib CAS:1228013-30-6
ATK CHEMICAL COMPANY LIMITED
HANGZHOU CLAP TECHNOLOGY CO.,LTD
BOC Sciences
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Zibo Hangyu Biotechnology Development Co., Ltd