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ChemicalBook >> CAS DataBase List >> CC-223

CC-223

CC-223 price.
  • $49 - $1320
  • Product name: CC-223
  • CAS: 1228013-30-6
  • MF: C21H27N5O3
  • MW: 397.47
  • EINECS:
  • MDL Number:MFCD28976054
  • Synonyms:CC-223;7-[6-(2-Hydroxypropan-2-yl)pyridin-3-yl]-1-(trans-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one;Pyrazino[2,3-b]pyrazin-2(1H)-one, 3,4-dihydro-7-[6-(1-hydroxy-1-methylethyl)-3-pyridinyl]-1-(trans-4-methoxycyclohexyl)-;Onatasertib;7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((1r,4r)-4-methoxycyclohexyl)-3,4-dihydropyrazino-[2,3-b]pyrazin-2(1H)-one;CS-2163;CS-2039;CC223;CC 223
Price17 Properties Safety Information Description
17 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number9870DN
  • Product descriptionCc-223
  • Packaging5mg
  • Price$297
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number9870DN
  • Product descriptionCc-223
  • Packaging10mg
  • Price$442
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0002487
  • Product descriptionCC-223 95.00%
  • Packaging5MG
  • Price$500.96
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6171
  • Product descriptionCC-223
  • Packaging5mg
  • Price$103
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6171
  • Product descriptionCC-223
  • Packaging25mg
  • Price$313
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19917
  • Product descriptionCC-223 ≥98%
  • Packaging1mg
  • Price$49
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19917
  • Product descriptionCC-223 ≥98%
  • Packaging5mg
  • Price$179
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19917
  • Product descriptionCC-223 ≥98%
  • Packaging10mg
  • Price$310
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19917
  • Product descriptionCC-223 ≥98%
  • Packaging25mg
  • Price$534
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4560
  • Product descriptionCC-223 99.43%
  • Packaging5mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4560
  • Product descriptionCC-223 99.43%
  • Packaging50mg
  • Price$900
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4560
  • Product descriptionCC-223 99.43%
  • Packaging100mg
  • Price$1320
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004195
  • Product descriptionCC-223 98+%
  • Packaging5mg
  • Price$84
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004195
  • Product descriptionCC-223 98+%
  • Packaging10mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004195
  • Product descriptionCC-223 98+%
  • Packaging50mg
  • Price$497
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004195
  • Product descriptionCC-223 98+%
  • Packaging100mg
  • Price$840
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9870DN Cc-223 5mg $297 2021-12-16 Buy
AK Scientific 9870DN Cc-223 10mg $442 2021-12-16 Buy
American Custom Chemicals Corporation KIN0002487 CC-223 95.00% 5MG $500.96 2021-12-16 Buy
ApexBio Technology B6171 CC-223 5mg $103 2021-12-16 Buy
ApexBio Technology B6171 CC-223 25mg $313 2021-12-16 Buy
Cayman Chemical 19917 CC-223 ≥98% 1mg $49 2024-03-01 Buy
Cayman Chemical 19917 CC-223 ≥98% 5mg $179 2024-03-01 Buy
Cayman Chemical 19917 CC-223 ≥98% 10mg $310 2024-03-01 Buy
Cayman Chemical 19917 CC-223 ≥98% 25mg $534 2024-03-01 Buy
ChemScene CS-4560 CC-223 99.43% 5mg $144 2021-12-16 Buy
ChemScene CS-4560 CC-223 99.43% 50mg $900 2021-12-16 Buy
ChemScene CS-4560 CC-223 99.43% 100mg $1320 2021-12-16 Buy
Crysdot CD31004195 CC-223 98+% 5mg $84 2021-12-16 Buy
Crysdot CD31004195 CC-223 98+% 10mg $133 2021-12-16 Buy
Crysdot CD31004195 CC-223 98+% 50mg $497 2021-12-16 Buy
Crysdot CD31004195 CC-223 98+% 100mg $840 2021-12-16 Buy
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Properties

Boiling point :562.9±60.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥108 mg/mL in DMSO; ≥20.28 mg/mL in EtOH
form :crystalline solid
pka :13?+-.0.29(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

CC-223 is a potent, selective, and orally bioavailable inhibitor of mTOR kinase, demonstrating inhibition of mTORC1 (pS6RP and p4EBP1) and mTORC2 [pAKT(S473)] in cellular systems. After tumor-bearing mice was treated with CC-223 for a single oral dose. It exhibited dose-dependent tumor growth inhibition in multiple solid tumor xenografts. The observed antitumor activity of CC-223 is likely to be mediated through inhibition of both mTORC1 and mTORC2. CC-223 is currently in phase I clinical trials for its treatment of advanced solid and hematologic cancers. 

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Suppliers and manufacturers

career henan chemical co
7-[6-(2-Hydroxy-2-propanyl)-3-pyridinyl]-1-(trans-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one
$1.00 /1KG
7-[6-(2-Hydroxy-2-propanyl)-3-pyridinyl]-1-(trans-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one CAS:1228013-30-6
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