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ChemicalBook >> CAS DataBase List >> CCG-1423

CCG-1423

CCG-1423 price.
  • $49 - $1600
  • Product name: CCG-1423
  • CAS: 285986-88-1
  • MF: C18H13ClF6N2O3
  • MW: 454.75
  • EINECS:
  • MDL Number:MFCD01566719
  • Synonyms:CCG-1423;N-(2-(4-Chloroanilino)-1-Methyl-2-oxoethoxy)-3,5-bis(trifluoroMethyl)benzaMide;N-(1-(4-chlorophenylaMino)-1-oxopropan-2-yloxy)-3,5-bis(trifluoroMethyl)benzaMide;N-({1-[(4-Chlorophenyl)Amino]-1-Oxo-2-Propanyl}Oxy)-3,5-Bis(Trifluoromethyl)Benzamide CCG-1423;N-[2-[(4-Chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)-benzamide;N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis(trifluoromethyl)benzamide;Rho/SRF Pathway Inhibitor, CCG-1423 ;CCG-1423 USP/EP/BP
Price34 Properties Safety Information Description
34 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 50mg
  • 100MG
  • 50
  • 5mg
  • 10mg
  • 25mg
  • 10mM(in 1mL DMSO)
  • 200mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberSYN5014
  • Product descriptionCCG-1423
  • Packaging50mg
  • Price$357
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA381687
  • Product descriptionCCG-1423 98+%
  • Packaging5mg
  • Price$104
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA381687
  • Product descriptionCCG-1423 98+%
  • Packaging10mg
  • Price$156
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA381687
  • Product descriptionCCG-1423 98+%
  • Packaging50mg
  • Price$344
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA381687
  • Product descriptionCCG-1423 98+%
  • Packaging250mg
  • Price$580
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4897
  • Product descriptionCCG-1423
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4897
  • Product descriptionCCG-1423
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4897
  • Product descriptionCCG-1423
  • Packaging50mg
  • Price$165
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4897
  • Product descriptionCCG-1423
  • Packaging200mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010350
  • Product descriptionCCG-1423 ≥98%
  • Packaging5mg
  • Price$49
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010350
  • Product descriptionCCG-1423 ≥98%
  • Packaging10mg
  • Price$82
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010350
  • Product descriptionCCG-1423 ≥98%
  • Packaging25mg
  • Price$179
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010350
  • Product descriptionCCG-1423 ≥98%
  • Packaging50mg
  • Price$286
  • Updated2024-03-01
  • Buy
  • ManufacturerChem-Impex
  • Product number42453
  • Product descriptionCCG-1423,≥98%(HPLC) ≥98%(HPLC)
  • Packaging25MG
  • Price$218.98
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number42453
  • Product descriptionCCG-1423,98%(HPLC) 98%(HPLC)
  • Packaging100MG
  • Price$677.6
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3689
  • Product descriptionCCG-1423 99.94%
  • Packaging10mg
  • Price$60
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5014 CCG-1423 50mg $357 2021-12-16 Buy
Ambeed A381687 CCG-1423 98+% 5mg $104 2021-12-16 Buy
Ambeed A381687 CCG-1423 98+% 10mg $156 2021-12-16 Buy
Ambeed A381687 CCG-1423 98+% 50mg $344 2021-12-16 Buy
Ambeed A381687 CCG-1423 98+% 250mg $580 2021-12-16 Buy
ApexBio Technology B4897 CCG-1423 10mg $50 2021-12-16 Buy
ApexBio Technology B4897 CCG-1423 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology B4897 CCG-1423 50mg $165 2021-12-16 Buy
ApexBio Technology B4897 CCG-1423 200mg $450 2021-12-16 Buy
Cayman Chemical 10010350 CCG-1423 ≥98% 5mg $49 2024-03-01 Buy
Cayman Chemical 10010350 CCG-1423 ≥98% 10mg $82 2024-03-01 Buy
Cayman Chemical 10010350 CCG-1423 ≥98% 25mg $179 2024-03-01 Buy
Cayman Chemical 10010350 CCG-1423 ≥98% 50mg $286 2024-03-01 Buy
Chem-Impex 42453 CCG-1423,≥98%(HPLC) ≥98%(HPLC) 25MG $218.98 2021-12-16 Buy
Chem-Impex 42453 CCG-1423,98%(HPLC) 98%(HPLC) 100MG $677.6 2021-12-16 Buy
ChemScene CS-3689 CCG-1423 99.94% 10mg $60 2021-12-16 Buy
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Properties

storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
form :White solid
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

CCG-1423 is a specific inhibitor of Rho pathway-mediated signalling and activation of serum response factor (SRF) transcription. The Rho family of small GTPases play a vital role in transduction of cell signalling events associated with several human cancers. It inhibits SRF-driven luciferase expression in PC-3 cells following stimulation with constitutively active Gα13 with an IC50 value of 1 μM. The site of inhibition in the pathway is not precisely defined but CCG-1423 appears to act on some aspect of the interaction of SRF with its transcriptional cofactor megakaryoblastic leukemia 1 (MKL1) at a point upstream of DNA binding. CCG-1423 selectively inhibits DNA synthesis, proliferation and invasion of Rho-overexpressing cell lines at nanomolar to low micromolar concentrations.

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N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis(trifluoromethyl)benzamide CAS:285986-88-1
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