CCG-1423
|
- $8 - $1600
- Product name: CCG-1423
- CAS: 285986-88-1
- MF: C18H13ClF6N2O3
- MW: 454.75
- EINECS:
- MDL Number:MFCD01566719
- Synonyms:CCG-1423;N-(2-(4-Chloroanilino)-1-Methyl-2-oxoethoxy)-3,5-bis(trifluoroMethyl)benzaMide;N-(1-(4-chlorophenylaMino)-1-oxopropan-2-yloxy)-3,5-bis(trifluoroMethyl)benzaMide;N-({1-[(4-Chlorophenyl)Amino]-1-Oxo-2-Propanyl}Oxy)-3,5-Bis(Trifluoromethyl)Benzamide CCG-1423;N-[2-[(4-Chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)-benzamide;N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis(trifluoromethyl)benzamide;Rho/SRF Pathway Inhibitor, CCG-1423 ;CCG-1423 USP/EP/BP
59 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- ApexBio Technology
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 200mg
- 10mM*1mLinDMSO
- 25mg
- 10
- 100.00g
- 50
- 50.00g
- 250.00g
- 10mM(in 1mL DMSO)
- 1mg
- 5mg
- 10mg
- 50mg
- 100mg
- 250mg
- 1G
- 10mM(in1mLDMSO)
- Manufactureraablocks
- Product numberAA002VQA
- Product descriptionBenzamide, N-[2-[(4-chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)- 99%
- Packaging1mg
- Price$8
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002VQA
- Product descriptionBenzamide, N-[2-[(4-chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)- 99%
- Packaging5mg
- Price$15
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002VQA
- Product descriptionBenzamide, N-[2-[(4-chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)- 99%
- Packaging10mg
- Price$19
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002VQA
- Product descriptionBenzamide, N-[2-[(4-chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)- 95%
- Packaging100mg
- Price$135
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002VQA
- Product descriptionBenzamide, N-[2-[(4-chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)- 95%
- Packaging250mg
- Price$248
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33880
- Product descriptionCCG1423 98%
- Packaging250MG
- Price$275
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33880
- Product descriptionCCG1423 98%
- Packaging100MG
- Price$160
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33880
- Product descriptionCCG1423 98%
- Packaging1G
- Price$825
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberSYN5014
- Product descriptionCCG-1423
- Packaging50mg
- Price$357
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA381687
- Product descriptionCCG-1423 98+%
- Packaging50mg
- Price$344
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA381687
- Product descriptionCCG-1423 98+%
- Packaging250mg
- Price$580
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA381687
- Product descriptionCCG-1423 98+%
- Packaging10mg
- Price$156
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA381687
- Product descriptionCCG-1423 98+%
- Packaging5mg
- Price$104
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4897
- Product descriptionCCG-1423
- Packaging10mM(in1mLDMSO)
- Price$61
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB4897
- Product descriptionCCG-1423
- Packaging10mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4897
- Product descriptionCCG-1423
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA002VQA | Benzamide, N-[2-[(4-chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)- 99% | 1mg | $8 | 2026-05-28 | Buy |
| aablocks | AA002VQA | Benzamide, N-[2-[(4-chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)- 99% | 5mg | $15 | 2026-05-28 | Buy |
| aablocks | AA002VQA | Benzamide, N-[2-[(4-chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)- 99% | 10mg | $19 | 2026-05-28 | Buy |
| aablocks | AA002VQA | Benzamide, N-[2-[(4-chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)- 95% | 100mg | $135 | 2026-05-28 | Buy |
| aablocks | AA002VQA | Benzamide, N-[2-[(4-chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)- 95% | 250mg | $248 | 2026-05-28 | Buy |
| ACHEMBLOCK | O33880 | CCG1423 98% | 250MG | $275 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33880 | CCG1423 98% | 100MG | $160 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33880 | CCG1423 98% | 1G | $825 | 2026-05-27 | Buy |
| AK Scientific | SYN5014 | CCG-1423 | 50mg | $357 | 2021-12-16 | Buy |
| Ambeed | A381687 | CCG-1423 98+% | 50mg | $344 | 2021-12-16 | Buy |
| Ambeed | A381687 | CCG-1423 98+% | 250mg | $580 | 2021-12-16 | Buy |
| Ambeed | A381687 | CCG-1423 98+% | 10mg | $156 | 2021-12-16 | Buy |
| Ambeed | A381687 | CCG-1423 98+% | 5mg | $104 | 2021-12-16 | Buy |
| ApexBio Technology | B4897 | CCG-1423 | 10mM(in1mLDMSO) | $61 | 2026-05-06 | Buy |
| ApexBio Technology | B4897 | CCG-1423 | 10mg | $50 | 2021-12-16 | Buy |
| ApexBio Technology | B4897 | CCG-1423 | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
Properties
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
form :White solid
color :white to beige
InChI :1S/C18H13ClF6N2O3/c1-9(15(28)26-14-4-2-13(19)3-5-14)30-27-16(29)10-6-11(17(20,21)22)8-12(7-10)18(23,24)25/h2-9H,1H3,(H,26,28)(H,27,29)
InChIKey :DSMXVSGJIDFLKP-UHFFFAOYSA-N
SMILES :FC(F)(F)c1cc(cc(c1)C(=O)NOC(C)C(=O)Nc2ccc(cc2)Cl)C(F)(F)F
solubility :DMSO: soluble5mg/mL, clear (warmed)
form :White solid
color :white to beige
InChI :1S/C18H13ClF6N2O3/c1-9(15(28)26-14-4-2-13(19)3-5-14)30-27-16(29)10-6-11(17(20,21)22)8-12(7-10)18(23,24)25/h2-9H,1H3,(H,26,28)(H,27,29)
InChIKey :DSMXVSGJIDFLKP-UHFFFAOYSA-N
SMILES :FC(F)(F)c1cc(cc(c1)C(=O)NOC(C)C(=O)Nc2ccc(cc2)Cl)C(F)(F)F
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | |||||||||||||||||||||
| Hazard statements: |
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| Precautionary statements: |
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Description
CCG-1423 is a specific inhibitor of Rho pathway-mediated signalling and activation of serum response factor (SRF) transcription. The Rho family of small GTPases play a vital role in transduction of cell signalling events associated with several human cancers. It inhibits SRF-driven luciferase expression in PC-3 cells following stimulation with constitutively active Gα13 with an IC50 value of 1 μM. The site of inhibition in the pathway is not precisely defined but CCG-1423 appears to act on some aspect of the interaction of SRF with its transcriptional cofactor megakaryoblastic leukemia 1 (MKL1) at a point upstream of DNA binding. CCG-1423 selectively inhibits DNA synthesis, proliferation and invasion of Rho-overexpressing cell lines at nanomolar to low micromolar concentrations.Related product price
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Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
Dideu Industries Group Limited
BOC Sciences
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
HANGZHOU LEAP CHEM CO., LTD.
![N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis(trifluoromethyl)benzamide](https://img.chemicalbook.com/ProductImageEN/2019-9/small/52a74ed7-749b-4502-bb97-fa685facc639.jpg){kind=small}
