CCT251545
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- $48 - $2600
- Product name: CCT251545
- CAS: 1661839-45-7
- MF: C23H24ClN5O
- MW: 421.92
- EINECS:
- MDL Number:MFCD29472582
- Synonyms:CCT251545;8-[3-Chloro-5-[4-(1-methyl-1H-pyrazol-4-yl)phenyl]-4-pyridinyl]-2,8-diazaspiro[4.5]decan-1-one;LM-3773,CCT251545;8-(3-chloro-5-(4-(1-methyl-1H-pyrazol-4-yl)phenyl)pyridin-4-yl)-2,8-diazaspiro[4.5]decan-1-one;2,8-Diazaspiro[4.5]decan-1-one, 8-[3-chloro-5-[4-(1-methyl-1H-pyrazol-4-yl)phenyl]-4-pyridinyl]-;CCT-251545;CCT 251545;CS-2537;inhibit,Wnt,CCT251545,Inhibitor,CCT-251545,CCT 251545
68 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Arctom
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 10mM*1mLinDMSO(Solution)
- 1mg
- 5mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 10mg
- 20mg
- 25mg
- 50mg
- 10mM(1mLinDMSO)
- 100mg
- 250MG
- 1g
- Manufactureraablocks
- Product numberAA001WGC
- Product descriptionCCT251545
- Packaging5mg
- Price$85
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001WGC
- Product descriptionCCT251545
- Packaging1mg
- Price$48
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001WGC
- Product descriptionCCT251545
- Packaging10mg
- Price$124
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001WGC
- Product descriptionCCT251545
- Packaging25mg
- Price$231
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001WGC
- Product descriptionCCT251545
- Packaging50mg
- Price$363
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001WGC
- Product descriptionCCT251545
- Packaging100mg
- Price$572
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberX203371
- Product descriptionCCT251545 98.00%
- Packaging100MG
- Price$825
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX203371
- Product descriptionCCT251545 98.00%
- Packaging250MG
- Price$1650
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number0185DY
- Product description8-[3-Chloro-5-[4-(1-methylpyrazol-4-yl)phenyl]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one
- Packaging5mg
- Price$310
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5979
- Product descriptionCCT251545
- Packaging5mg
- Price$163
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5979
- Product descriptionCCT251545
- Packaging10mg
- Price$271
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5979
- Product descriptionCCT251545
- Packaging20mg
- Price$286
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5979
- Product descriptionCCT251545
- Packaging10mg
- Price$176
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5979
- Product descriptionCCT251545
- Packaging5mg
- Price$110
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5979
- Product descriptionCCT251545
- Packaging50mg
- Price$572
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5979
- Product descriptionCCT251545
- Packaging20mg
- Price$379
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA001WGC | CCT251545 | 5mg | $85 | 2026-05-28 | Buy |
| aablocks | AA001WGC | CCT251545 | 1mg | $48 | 2026-05-28 | Buy |
| aablocks | AA001WGC | CCT251545 | 10mg | $124 | 2026-05-28 | Buy |
| aablocks | AA001WGC | CCT251545 | 25mg | $231 | 2026-05-28 | Buy |
| aablocks | AA001WGC | CCT251545 | 50mg | $363 | 2026-05-28 | Buy |
| aablocks | AA001WGC | CCT251545 | 100mg | $572 | 2026-05-28 | Buy |
| ACHEMBLOCK | X203371 | CCT251545 98.00% | 100MG | $825 | 2026-05-27 | Buy |
| ACHEMBLOCK | X203371 | CCT251545 98.00% | 250MG | $1650 | 2026-05-27 | Buy |
| AK Scientific | 0185DY | 8-[3-Chloro-5-[4-(1-methylpyrazol-4-yl)phenyl]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one | 5mg | $310 | 2021-12-16 | Buy |
| ApexBio Technology | B5979 | CCT251545 | 5mg | $163 | 2021-12-16 | Buy |
| ApexBio Technology | B5979 | CCT251545 | 10mg | $271 | 2021-12-16 | Buy |
| ApexBio Technology | B5979 | CCT251545 | 20mg | $286 | 2026-05-06 | Buy |
| ApexBio Technology | B5979 | CCT251545 | 10mg | $176 | 2026-05-06 | Buy |
| ApexBio Technology | B5979 | CCT251545 | 5mg | $110 | 2026-05-06 | Buy |
| ApexBio Technology | B5979 | CCT251545 | 50mg | $572 | 2026-05-06 | Buy |
| ApexBio Technology | B5979 | CCT251545 | 20mg | $379 | 2021-12-16 | Buy |
Properties
Boiling point :709.7±60.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :≥42.2 mg/mL in DMSO; insoluble in H2O; ≥2.33 mg/mL in EtOH with ultrasonic
form :solid
pka :15.81±0.20(Predicted)
color :White to off-white
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :≥42.2 mg/mL in DMSO; insoluble in H2O; ≥2.33 mg/mL in EtOH with ultrasonic
form :solid
pka :15.81±0.20(Predicted)
color :White to off-white
Safety Information
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Description
CCT251545 is an orally bioavailable inhibitor of Wnt signaling (IC50 = 5 nM). It is a potent and selective inhibitor of the human mediator complex-associated protein kinases Cdk8 and Cdk19. Through its effects on Cdk8 and Cdk19, CCT251545 alters Wnt pathway-regulated gene expression. It reduces tumor growth in COLO 205 human colon cancer xenografts after oral dosing (70 mg/kg bid) and in Wnt-dependent tumors.More related product prices
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