CEP 33779
|
- $55 - $2000
- Product name: CEP 33779
- CAS: 1257704-57-6
- MF: C24H26N6O2S
- MW: 462.57
- EINECS:
- MDL Number:MFCD22683932
- Synonyms:[8-(4-Methylsulfonylphenyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl][3-(4-methylpiperazin-1-yl)phenyl]amine;N-[3-(4-Methyl-1-piperazinyl)phenyl]-8-[4-(methylsulfonyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine;[1,2,4]Triazolo[1,5-a]pyridin-2-amine, N-[3-(4-methyl-1-piperazinyl)phenyl]-8-[4-(methylsulfonyl)phenyl]-;N-(3-(4-Methylpiperazin-1-yl)phenyl)-8-(4-(methylsulfonyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridi;N-[3-(4-methylpiperazin-1-yl)phenyl]-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;CEP 33779 USP/EP/BP;CS-1066;CEP33779; CEP-33779; CEP 33779.
17 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 500μg
- 1mg
- 5mg
- 10mg
- 50mg
- 100mg
- 1g
- ManufacturerAK Scientific
- Product number2311AH
- Product descriptionN-[3-(4-Methyl-1-piperazinyl)phenyl]-8-[4-(methylsulfonyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine
- Packaging1g
- Price$1469
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4146
- Product descriptionCEP-33779
- Packaging10mg
- Price$230
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4146
- Product descriptionCEP-33779
- Packaging50mg
- Price$770
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC137660
- Product descriptionCEP 33779
- Packaging10mg
- Price$185
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC137660
- Product descriptionCEP 33779
- Packaging50mg
- Price$647.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16732
- Product descriptionCEP-33779 ≥95%
- Packaging500μg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16732
- Product descriptionCEP-33779 ≥95%
- Packaging1mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16732
- Product descriptionCEP-33779 ≥95%
- Packaging5mg
- Price$281
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-3439
- Product descriptionCEP-33779 99.36%
- Packaging5mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3439
- Product descriptionCEP-33779 99.36%
- Packaging10mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3439
- Product descriptionCEP-33779 99.36%
- Packaging100mg
- Price$750
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3439
- Product descriptionCEP-33779 99.36%
- Packaging50mg
- Price$750
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004068
- Product descriptionCEP-33779 98+%
- Packaging10mg
- Price$226
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004068
- Product descriptionCEP-33779 98+%
- Packaging50mg
- Price$779
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004068
- Product descriptionCEP-33779 98+%
- Packaging100mg
- Price$1128
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7099
- Product descriptionCEP33779 >98%
- Packaging1g
- Price$2000
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2311AH | N-[3-(4-Methyl-1-piperazinyl)phenyl]-8-[4-(methylsulfonyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine | 1g | $1469 | 2021-12-16 | Buy |
| ApexBio Technology | A4146 | CEP-33779 | 10mg | $230 | 2021-12-16 | Buy |
| ApexBio Technology | A4146 | CEP-33779 | 50mg | $770 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC137660 | CEP 33779 | 10mg | $185 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC137660 | CEP 33779 | 50mg | $647.5 | 2021-12-16 | Buy |
| Cayman Chemical | 16732 | CEP-33779 ≥95% | 500μg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 16732 | CEP-33779 ≥95% | 1mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 16732 | CEP-33779 ≥95% | 5mg | $281 | 2024-03-01 | Buy |
| ChemScene | CS-3439 | CEP-33779 99.36% | 5mg | $110 | 2021-12-16 | Buy |
| ChemScene | CS-3439 | CEP-33779 99.36% | 10mg | $180 | 2021-12-16 | Buy |
| ChemScene | CS-3439 | CEP-33779 99.36% | 100mg | $750 | 2021-12-16 | Buy |
| ChemScene | CS-3439 | CEP-33779 99.36% | 50mg | $750 | 2021-12-16 | Buy |
| Crysdot | CD31004068 | CEP-33779 98+% | 10mg | $226 | 2021-12-16 | Buy |
| Crysdot | CD31004068 | CEP-33779 98+% | 50mg | $779 | 2021-12-16 | Buy |
| Crysdot | CD31004068 | CEP-33779 98+% | 100mg | $1128 | 2021-12-16 | Buy |
| DC Chemicals | DC7099 | CEP33779 >98% | 1g | $2000 | 2021-12-16 | Buy |
Properties
Density :1.35
storage temp. :Store at -20°C
solubility :≥23.15 mg/mL in DMSO with gentle warming; insoluble in EtOH
form :solid
pka :7.78±0.42(Predicted)
storage temp. :Store at -20°C
solubility :≥23.15 mg/mL in DMSO with gentle warming; insoluble in EtOH
form :solid
pka :7.78±0.42(Predicted)
Safety Information
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Description
Janus kinases (JAKs) are non-receptor kinases that mediate signaling through cytokine receptors, often to members of the signal transducer and activator of transcription family. CEP-33779 is a potent, orally available inhibitor of JAK2 (IC50 = 1.3 nM). It shows 65-fold selectivity for JAK2 over JAK3. In mouse models of systemic lupus erythematosus, CEP-33779 reduces the production of inflammatory cytokines, decreases splenomegaly and lymphomegaly, and extends survival. It also diminishes inflammatory signaling and improves clinical scores in mice during collagen antibody-induced arthritis and collagen type II-induced arthritis. CEP-33779 induces regression of established colorectal tumors in mice, reducing angiogenesis and proliferation of tumor cells.Related product price
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