CHIR 98014
|
- $55 - $1647
- Product name: CHIR 98014
- CAS: 556813-39-9
- MF: C20H17Cl2N9O2
- MW: 486.31
- EINECS:
- MDL Number:MFCD24369684
- Synonyms:CHIR 98014;N6-[2-[[4-(2,4-Dichlorophenyl)-5-(1H-iMidazol-2-yl)-2-pyriMidinyl]aMino]ethyl]-3-nitro- 2,6-pyridinediaMine;N2-(2-((4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)-5-nitropyridine-2,;N2-(2-((4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)-5-nitropyridine;N2-(2-((4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)-5-nitropyridine-2,6-diamine;CHIR 98014;CHIR98014;CHIR-98014;CT98014;CT98014;CS-71
29 prices
Selected condition：
Brand
- AK Scientific
- Alichem
- Ambeed
- American Custom Chemicals Corporation
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- Crysdot
- CSNpharm
- Matrix Scientific
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 5
- 2mg
- 1mg
- 10mg
- 25
- 25mg
- 50mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number8126AB
- Product descriptionN2-(2-((4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)-5-nitropyridine-2,6-diamine
- Packaging2mg
- Price$116
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number556813399
- Product descriptionN2-(2-((4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)-5-nitropyridine-2,6-diamine
- Packaging10mg
- Price$230.05
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number556813399
- Product descriptionN2-(2-((4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)-5-nitropyridine-2,6-diamine
- Packaging50mg
- Price$763.56
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA179486
- Product descriptionCHIR-98024 95+%
- Packaging2mg
- Price$69
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA179486
- Product descriptionCHIR-98024 95+%
- Packaging5mg
- Price$123
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA179486
- Product descriptionCHIR-98024 95+%
- Packaging10mg
- Price$209
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA179486
- Product descriptionCHIR-98024 95+%
- Packaging25mg
- Price$354
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA179486
- Product descriptionCHIR-98024 95+%
- Packaging50mg
- Price$461
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0002524
- Product descriptionN-6-[2-[[4-(2,4-DICHLOROPHENYL)-5-(1H-IMIDAZOL-2-YL)-2-PYRIMIDINYL]AMINO]ETHYL]-3-NITRO-2,6-PYRIDINEDIAMINE 95.00%
- Packaging5MG
- Price$451.34
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC19922
- Product descriptionCHIR 98014
- Packaging10mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC19922
- Product descriptionCHIR 98014
- Packaging50mg
- Price$437.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15578
- Product descriptionCHIR98014 ≥98%
- Packaging1mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15578
- Product descriptionCHIR98014 ≥98%
- Packaging5mg
- Price$146
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15578
- Product descriptionCHIR98014 ≥98%
- Packaging10mg
- Price$260
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15578
- Product descriptionCHIR98014 ≥98%
- Packaging25mg
- Price$553
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM166538
- Product descriptionN2-(2-((4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)-5-nitropyridine-2,6-diamine 95%
- Packaging10mg
- Price$201
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8126AB | N2-(2-((4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)-5-nitropyridine-2,6-diamine | 2mg | $116 | 2021-12-16 | Buy |
| Alichem | 556813399 | N2-(2-((4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)-5-nitropyridine-2,6-diamine | 10mg | $230.05 | 2021-12-16 | Buy |
| Alichem | 556813399 | N2-(2-((4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)-5-nitropyridine-2,6-diamine | 50mg | $763.56 | 2021-12-16 | Buy |
| Ambeed | A179486 | CHIR-98024 95+% | 2mg | $69 | 2021-12-16 | Buy |
| Ambeed | A179486 | CHIR-98024 95+% | 5mg | $123 | 2021-12-16 | Buy |
| Ambeed | A179486 | CHIR-98024 95+% | 10mg | $209 | 2021-12-16 | Buy |
| Ambeed | A179486 | CHIR-98024 95+% | 25mg | $354 | 2021-12-16 | Buy |
| Ambeed | A179486 | CHIR-98024 95+% | 50mg | $461 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0002524 | N-6-[2-[[4-(2,4-DICHLOROPHENYL)-5-(1H-IMIDAZOL-2-YL)-2-PYRIMIDINYL]AMINO]ETHYL]-3-NITRO-2,6-PYRIDINEDIAMINE 95.00% | 5MG | $451.34 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC19922 | CHIR 98014 | 10mg | $125 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC19922 | CHIR 98014 | 50mg | $437.5 | 2021-12-16 | Buy |
| Cayman Chemical | 15578 | CHIR98014 ≥98% | 1mg | $65 | 2021-12-16 | Buy |
| Cayman Chemical | 15578 | CHIR98014 ≥98% | 5mg | $146 | 2021-12-16 | Buy |
| Cayman Chemical | 15578 | CHIR98014 ≥98% | 10mg | $260 | 2021-12-16 | Buy |
| Cayman Chemical | 15578 | CHIR98014 ≥98% | 25mg | $553 | 2021-12-16 | Buy |
| Chemenu | CM166538 | N2-(2-((4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)-5-nitropyridine-2,6-diamine 95% | 10mg | $201 | 2021-12-16 | Buy |
Properties
Melting point :192-196°C
Boiling point :839.0±75.0 °C(Predicted)
Density :1.573±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :DMSO: slightly soluble,Ethanol: slightly soluble
form :A solid
pka :10.98±0.10(Predicted)
color :Light yellow to yellow
Boiling point :839.0±75.0 °C(Predicted)
Density :1.573±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :DMSO: slightly soluble,Ethanol: slightly soluble
form :A solid
pka :10.98±0.10(Predicted)
color :Light yellow to yellow
Safety Information
| Symbol(GHS): |
 
|
||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Danger | ||||||||||||||||||||||||||||||||
| Hazard statements: |
|
||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
The two isoforms of glycogen synthase kinase 3, GSK3α and GSK3β, constitutively phosphorylates and inactivates glycogen synthase, preventing glycogen synthesis. They also phosphorylate proteins that are relevant to Alzheimer’s disease and osteogenesis. CHIR98014 is a reversible, cell-permeable inhibitor of GSK3α and GSK3β (IC50 = 0.65 and 0.58 nM, respectively). It is inactive against a series of other serine/threonine or tyrosine kinases. Through its effects on GSK3, CHIR98014 stimulates glycogen synthase in cells (EC50 = 106 nM), potentiates insulin-dependent glucose transport in isolated muscle strips, and improves glucose disposal in diabetic animals. CHIR98014 also reduces tau phosphorylation in rat brains and supports Wnt signaling during osteogenesis.Suppliers and manufacturers
Nanjing Doge Biomedical Technology Co., Ltd
Coresyn Pharmatech Co., Ltd.
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd
HANGZHOU LEAP CHEM CO., LTD.
Aladdin Scientific
Aladdin Scientific
Amadis Chemical Company Limited
