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ChemicalBook >> CAS DataBase List >> CID-2858522

CID-2858522

CID-2858522 price.
  • $37 - $1800
  • Product name: CID-2858522
  • CAS: 758679-97-9
  • MF: C28H39N3O3
  • MW: 465.63
  • EINECS:804-713-5
  • MDL Number:MFCD20755108
  • Synonyms:CID-2858522;1-(3,5-di-tert-butyl-4-hydroxyphenyl)-2-(2-(3-hydroxypropylaMino)-5,6-diMethyl-1H-benzo[d]iMidazol-1-yl)ethanone;1-[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-[2-[(3-hydroxypropyl)amino]-5,6-dimethyl-1H-benzimidazol-1-yl]-ethanone;1-(3,5-Di-tert-butyl-4-hydroxyphenyl)-2-(2-(3-hydroxypropylamino)-5,6-dimethyl-1H-benzo[d]imid;CID 2858522;CID2858522;100844;Ethanone, 1-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-[2-[(3-hydroxypropyl)amino]-5,6-dimethyl-1H-benzimidazol-1-yl]-;CID 2858522,Nuclear factor-kappaB,CID-2858522,NF-κB,Nuclear factor-κB,inhibit,CID2858522,Inhibitor
Price26 Properties Safety Information Description
26 prices
Selected condition：
Brand
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 5MG
  • 10mg
  • 1mg
  • 10
  • 25MG
  • 50mg
  • 100MG
  • 250mg
  • 1g
  • ManufacturerACHEMBLOCK
  • Product numberO32762
  • Product description1-(3,5-Di-tert-butyl-4-hydroxyphenyl)-2-(2-(3-hydroxypropylamino)-5,6-dimethyl-1H-benzo[d]imidazol-1-yl)ethanone 98%
  • Packaging5MG
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO32762
  • Product description1-(3,5-Di-tert-butyl-4-hydroxyphenyl)-2-(2-(3-hydroxypropylamino)-5,6-dimethyl-1H-benzo[d]imidazol-1-yl)ethanone 98%
  • Packaging25MG
  • Price$245
  • Updated2021-12-16
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO32762
  • Product description1-(3,5-Di-tert-butyl-4-hydroxyphenyl)-2-(2-(3-hydroxypropylamino)-5,6-dimethyl-1H-benzo[d]imidazol-1-yl)ethanone 98%
  • Packaging100MG
  • Price$695
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3547AH
  • Product description1-(3,5-Di-tert-Butyl-4-hydroxyphenyl)-2-(2-((3-hydroxypropyl)amino)-5,6-dimethyl-1H-benzo[d]imidazol-1-yl)ethanone
  • Packaging1mg
  • Price$139
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3547AH
  • Product description1-(3,5-Di-tert-Butyl-4-hydroxyphenyl)-2-(2-((3-hydroxypropyl)amino)-5,6-dimethyl-1H-benzo[d]imidazol-1-yl)ethanone
  • Packaging10mg
  • Price$237
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3547AH
  • Product description1-(3,5-Di-tert-Butyl-4-hydroxyphenyl)-2-(2-((3-hydroxypropyl)amino)-5,6-dimethyl-1H-benzo[d]imidazol-1-yl)ethanone
  • Packaging25mg
  • Price$394
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPRK0000430
  • Product description1-[3,5-BIS(1,1-DIMETHYLETHYL)-4-HYDROXYPHENYL]-2-[2-[(3-HYDROXYPROPYL)AMINO]-5,6-DIMETHYL-1H-BENZIMIDAZOL-1-YL]-ETHANONE 95.00%
  • Packaging5MG
  • Price$498.76
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3311
  • Product descriptionCID-2858522
  • Packaging5mg
  • Price$88
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3311
  • Product descriptionCID-2858522
  • Packaging10mg
  • Price$158
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14122
  • Product descriptionCID-2858522 ≥98%
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14122
  • Product descriptionCID-2858522 ≥98%
  • Packaging5mg
  • Price$72
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14122
  • Product descriptionCID-2858522 ≥98%
  • Packaging10mg
  • Price$127
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14122
  • Product descriptionCID-2858522 ≥98%
  • Packaging25mg
  • Price$266
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1093
  • Product descriptionCID-2858522 96.57%
  • Packaging5mg
  • Price$67
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1093
  • Product descriptionCID-2858522 96.57%
  • Packaging10mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000857
  • Product descriptionCID-2858522 98+%
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ACHEMBLOCK O32762 1-(3,5-Di-tert-butyl-4-hydroxyphenyl)-2-(2-(3-hydroxypropylamino)-5,6-dimethyl-1H-benzo[d]imidazol-1-yl)ethanone 98% 5MG $95 2021-12-16 Buy
ACHEMBLOCK O32762 1-(3,5-Di-tert-butyl-4-hydroxyphenyl)-2-(2-(3-hydroxypropylamino)-5,6-dimethyl-1H-benzo[d]imidazol-1-yl)ethanone 98% 25MG $245 2021-12-16 Buy
ACHEMBLOCK O32762 1-(3,5-Di-tert-butyl-4-hydroxyphenyl)-2-(2-(3-hydroxypropylamino)-5,6-dimethyl-1H-benzo[d]imidazol-1-yl)ethanone 98% 100MG $695 2021-12-16 Buy
AK Scientific 3547AH 1-(3,5-Di-tert-Butyl-4-hydroxyphenyl)-2-(2-((3-hydroxypropyl)amino)-5,6-dimethyl-1H-benzo[d]imidazol-1-yl)ethanone 1mg $139 2021-12-16 Buy
AK Scientific 3547AH 1-(3,5-Di-tert-Butyl-4-hydroxyphenyl)-2-(2-((3-hydroxypropyl)amino)-5,6-dimethyl-1H-benzo[d]imidazol-1-yl)ethanone 10mg $237 2021-12-16 Buy
AK Scientific 3547AH 1-(3,5-Di-tert-Butyl-4-hydroxyphenyl)-2-(2-((3-hydroxypropyl)amino)-5,6-dimethyl-1H-benzo[d]imidazol-1-yl)ethanone 25mg $394 2021-12-16 Buy
American Custom Chemicals Corporation PRK0000430 1-[3,5-BIS(1,1-DIMETHYLETHYL)-4-HYDROXYPHENYL]-2-[2-[(3-HYDROXYPROPYL)AMINO]-5,6-DIMETHYL-1H-BENZIMIDAZOL-1-YL]-ETHANONE 95.00% 5MG $498.76 2021-12-16 Buy
ApexBio Technology A3311 CID-2858522 5mg $88 2021-12-16 Buy
ApexBio Technology A3311 CID-2858522 10mg $158 2021-12-16 Buy
Cayman Chemical 14122 CID-2858522 ≥98% 1mg $37 2024-03-01 Buy
Cayman Chemical 14122 CID-2858522 ≥98% 5mg $72 2024-03-01 Buy
Cayman Chemical 14122 CID-2858522 ≥98% 10mg $127 2024-03-01 Buy
Cayman Chemical 14122 CID-2858522 ≥98% 25mg $266 2024-03-01 Buy
ChemScene CS-1093 CID-2858522 96.57% 5mg $67 2021-12-16 Buy
ChemScene CS-1093 CID-2858522 96.57% 10mg $120 2021-12-16 Buy
Crysdot CD31000857 CID-2858522 98+% 10mg $70 2021-12-16 Buy
Next Last

Properties

Boiling point :618.9±65.0 °C(Predicted)
Density :1.12±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble2mg/mL, clear (warmed)
pka :8.46±0.40(Predicted)
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

CID-2858522 is an 2-amino benzimidazole that inhibits activation of the NF-κB pathway induced by the PKC activator PMA with an IC50 value of 0.07 μM. It has been shown to inhibit IL-8 production induced by PKC activators in HEK293 cells (IC50 ≤ 0.1 μM), attenuate CD3/CD28 and PMA/ionomycin-induced production of IL-2 by Jurkat T cells (IC50 ≤ 5 μM), and prevent anti-IgM-stimulated proliferation of mouse B-lymphocytes (IC50 = ～2 μM). CID-2858522 does not, however, inhibit the NF-κB pathway activated by TNF-α.

Suppliers and manufacturers

ATK CHEMICAL COMPANY LIMITED
Alchem Pharmtech,Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Aladdin Scientific J & K SCIENTIFIC LTD. ChemShuttle, Inc. Haoyuan Chemexpress Co., Ltd. AdooQ BioScience, LLC CEG Chemical Science&Technology Co., Ltd. Shanghai HuanChuan Industry Co.,Ltd.