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ChemicalBook >> CAS DataBase List >> CPI 360

CPI 360

$41 - $2900
Product name: CPI 360
CAS: 1802175-06-9
MF: C25H31N3O4
MW: 437.53
EINECS:
MDL Number:MFCD28167834
Synonyms:CPI 360;CPI360;CPI360;CPI 360;CPI-360 (R);1H-Indole-3-carboxamide, N-[(1,2-dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-;CPI-360 ，S7656;CPI-360

Price29 Properties Safety Information Description

29 prices

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Brand

aablocks
ACHEMBLOCK
AK Scientific
ApexBio Technology
Arctom
Biosynth
Cayman Chemical
ChemScene
Crysdot
DC Chemicals

Package

500μg
1mg
2mg
5mg
10mg
25mg
50mg
100mg
250mg
1g

Manufactureraablocks
Product numberAA00ABKP
Product descriptionN-[(1,2-Dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-indole-3-carboxamide ≥98%
Packaging1mg
Price$75
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00ABKP
Product descriptionN-[(1,2-Dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-indole-3-carboxamide
Packaging5mg
Price$160
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00ABKP
Product descriptionN-[(1,2-Dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-indole-3-carboxamide
Packaging10mg
Price$248
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00ABKP
Product descriptionN-[(1,2-Dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-indole-3-carboxamide
Packaging25mg
Price$403
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00ABKP
Product descriptionN-[(1,2-Dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-indole-3-carboxamide
Packaging50mg
Price$570
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product numberY229056
Product descriptionCPI-360 97.00%
Packaging10MG
Price$340
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberY229056
Product descriptionCPI-360 97.00%
Packaging50MG
Price$820
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product number6715DW
Product descriptionCID73442743
Packaging10mg
Price$569
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB4836
Product descriptionCPI-360
Packaging10mg
Price$405
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberB4836
Product descriptionCPI-360
Packaging5mg
Price$249
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberB4836
Product descriptionCPI-360
Packaging2mg
Price$165
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberB4836
Product descriptionCPI-360
Packaging50mg
Price$1418
Updated2026-05-06
Buy

ManufacturerArctom
Product numberSLK-S7656
Product descriptionCPI-360 99.72%
Packaging5mg
Price$188
Updated2026-05-26
Buy

ManufacturerArctom
Product numberSLK-S7656
Product descriptionCPI-360 99.72%
Packaging25mg
Price$663
Updated2026-05-26
Buy

ManufacturerBiosynth
Product numberCXC17506
Product descriptionCPI-360
Packaging25mg
Price$1429
Updated2026-06-04
Buy

ManufacturerBiosynth
Product numberCXC17506
Product descriptionCPI-360
Packaging50mg
Price$1988.5
Updated2026-06-04
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00ABKP	N-[(1,2-Dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-indole-3-carboxamide ≥98%	1mg	$75	2026-05-28	Buy
aablocks	AA00ABKP	N-[(1,2-Dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-indole-3-carboxamide	5mg	$160	2026-05-28	Buy
aablocks	AA00ABKP	N-[(1,2-Dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-indole-3-carboxamide	10mg	$248	2026-05-28	Buy
aablocks	AA00ABKP	N-[(1,2-Dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-indole-3-carboxamide	25mg	$403	2026-05-28	Buy
aablocks	AA00ABKP	N-[(1,2-Dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-indole-3-carboxamide	50mg	$570	2026-05-28	Buy
ACHEMBLOCK	Y229056	CPI-360 97.00%	10MG	$340	2026-05-27	Buy
ACHEMBLOCK	Y229056	CPI-360 97.00%	50MG	$820	2026-05-27	Buy
AK Scientific	6715DW	CID73442743	10mg	$569	2021-12-16	Buy
ApexBio Technology	B4836	CPI-360	10mg	$405	2026-05-06	Buy
ApexBio Technology	B4836	CPI-360	5mg	$249	2026-05-06	Buy
ApexBio Technology	B4836	CPI-360	2mg	$165	2026-05-06	Buy
ApexBio Technology	B4836	CPI-360	50mg	$1418	2026-05-06	Buy
Arctom	SLK-S7656	CPI-360 99.72%	5mg	$188	2026-05-26	Buy
Arctom	SLK-S7656	CPI-360 99.72%	25mg	$663	2026-05-26	Buy
Biosynth	CXC17506	CPI-360	25mg	$1429	2026-06-04	Buy
Biosynth	CXC17506	CPI-360	50mg	$1988.5	2026-06-04	Buy

Next Last

Properties

Boiling point :712.2±60.0 °C(Predicted)
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 10 mg/mL; DMSO: 25 mg/mL; Ethanol: 30 mg/mL; Ethanol:PBS (pH7.2) (1:7): 0.12 mg/mL
form :A crystalline solid
pka :11.01±0.10(Predicted)
InChIKey :PFPSFENQCNMITC-MRXNPFEDSA-N
SMILES :N1([C@@H](C2CCOCC2)C)C2=C(C=CC=C2)C(C(NCC2=C(OC)C=C(C)NC2=O)=O)=C1C

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

CPI-360 is a selective EZH2 inhibitor with IC₅₀ values of 0.5 and 2.5 nM for wild-type EZH2 and Y641N mutant EZH2, respectively. It decreases cellular levels of H3K27me3 and H3K27me2 (EC₅₀s = 56 and 65 nM, respectively), triggering cell cycle arrest and ultimately resulting in apoptosis in a large panel of non-Hodgkin’s lymphoma (NHL) cell lines. Twice daily, subcutaneous administration of 200 mg/kg of CPI-360 reduced tumor growth of KARPAS-422 xenografts in mice.

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career henan chemical co

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BOC Sciences

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CPI 360

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