CPI 360
|
- $37 - $2900
- Product name: CPI 360
- CAS: 1802175-06-9
- MF: C25H31N3O4
- MW: 437.53
- EINECS:
- MDL Number:MFCD28167834
- Synonyms:CPI 360;CPI360;CPI-360;CPI360;CPI 360;CPI-360 (R);1H-Indole-3-carboxamide, N-[(1,2-dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-
16 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
Package
- 500μg
- 1mg
- 2mg
- 5mg
- 10mg
- 50mg
- 100mg
- 1g
- ManufacturerAK Scientific
- Product number6715DW
- Product descriptionCID73442743
- Packaging10mg
- Price$569
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4836
- Product descriptionCPI-360
- Packaging2mg
- Price$167
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4836
- Product descriptionCPI-360
- Packaging5mg
- Price$252
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4836
- Product descriptionCPI-360
- Packaging10mg
- Price$410
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4836
- Product descriptionCPI-360
- Packaging50mg
- Price$1433
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19125
- Product descriptionCPI-360 ≥98%
- Packaging10mg
- Price$424
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19125
- Product descriptionCPI-360 ≥98%
- Packaging5mg
- Price$231
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19125
- Product descriptionCPI-360 ≥98%
- Packaging1mg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19125
- Product descriptionCPI-360 ≥98%
- Packaging500μg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-3437
- Product descriptionCPI-360 99.43%
- Packaging5mg
- Price$216
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3437
- Product descriptionCPI-360 99.43%
- Packaging10mg
- Price$360
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3437
- Product descriptionCPI-360 99.43%
- Packaging50mg
- Price$1140
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3437
- Product descriptionCPI-360 99.43%
- Packaging100mg
- Price$2040
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002912
- Product descriptionCPI-360 98+%
- Packaging5mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8002
- Product descriptionCPI-360(R) >98%
- Packaging100mg
- Price$750
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8002
- Product descriptionCPI-360(R) >98%
- Packaging1g
- Price$2900
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 6715DW | CID73442743 | 10mg | $569 | 2021-12-16 | Buy |
| ApexBio Technology | B4836 | CPI-360 | 2mg | $167 | 2021-12-16 | Buy |
| ApexBio Technology | B4836 | CPI-360 | 5mg | $252 | 2021-12-16 | Buy |
| ApexBio Technology | B4836 | CPI-360 | 10mg | $410 | 2021-12-16 | Buy |
| ApexBio Technology | B4836 | CPI-360 | 50mg | $1433 | 2021-12-16 | Buy |
| Cayman Chemical | 19125 | CPI-360 ≥98% | 10mg | $424 | 2024-03-01 | Buy |
| Cayman Chemical | 19125 | CPI-360 ≥98% | 5mg | $231 | 2024-03-01 | Buy |
| Cayman Chemical | 19125 | CPI-360 ≥98% | 1mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 19125 | CPI-360 ≥98% | 500μg | $37 | 2024-03-01 | Buy |
| ChemScene | CS-3437 | CPI-360 99.43% | 5mg | $216 | 2021-12-16 | Buy |
| ChemScene | CS-3437 | CPI-360 99.43% | 10mg | $360 | 2021-12-16 | Buy |
| ChemScene | CS-3437 | CPI-360 99.43% | 50mg | $1140 | 2021-12-16 | Buy |
| ChemScene | CS-3437 | CPI-360 99.43% | 100mg | $2040 | 2021-12-16 | Buy |
| Crysdot | CD31002912 | CPI-360 98+% | 5mg | $250 | 2021-12-16 | Buy |
| DC Chemicals | DC8002 | CPI-360(R) >98% | 100mg | $750 | 2021-12-16 | Buy |
| DC Chemicals | DC8002 | CPI-360(R) >98% | 1g | $2900 | 2021-12-16 | Buy |
Properties
Boiling point :712.2±60.0 °C(Predicted)
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 10 mg/mL; DMSO: 25 mg/mL; Ethanol: 30 mg/mL; Ethanol:PBS (pH7.2) (1:7): 0.12 mg/mL
form :A crystalline solid
pka :11.01±0.10(Predicted)
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 10 mg/mL; DMSO: 25 mg/mL; Ethanol: 30 mg/mL; Ethanol:PBS (pH7.2) (1:7): 0.12 mg/mL
form :A crystalline solid
pka :11.01±0.10(Predicted)
Safety Information
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Description
CPI-360 is a selective EZH2 inhibitor with IC50 values of 0.5 and 2.5 nM for wild-type EZH2 and Y641N mutant EZH2, respectively. It decreases cellular levels of H3K27me3 and H3K27me2 (EC50s = 56 and 65 nM, respectively), triggering cell cycle arrest and ultimately resulting in apoptosis in a large panel of non-Hodgkin’s lymphoma (NHL) cell lines. Twice daily, subcutaneous administration of 200 mg/kg of CPI-360 reduced tumor growth of KARPAS-422 xenografts in mice.Suppliers and manufacturers
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
Aladdin Scientific
Wuhan Jingkang en Biomedical Technology Co., Ltd
Amadis Chemical Company Limited
Zhengzhou convergence chemical co., LTD
Hubei Chuchang Chemical Co., Ltd
