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ChemicalBook >> CAS DataBase List >> CPI 360

CPI 360

CPI 360 price.
  • $41 - $2900
  • Product name: CPI 360
  • CAS: 1802175-06-9
  • MF: C25H31N3O4
  • MW: 437.53
  • EINECS:
  • MDL Number:MFCD28167834
  • Synonyms:CPI 360;CPI360;CPI360;CPI 360;CPI-360 (R);1H-Indole-3-carboxamide, N-[(1,2-dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-;CPI-360 ，S7656;CPI-360
Price29 Properties Safety Information Description
29 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
Package
  • 500μg
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • Manufactureraablocks
  • Product numberAA00ABKP
  • Product descriptionN-[(1,2-Dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-indole-3-carboxamide ≥98%
  • Packaging1mg
  • Price$75
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABKP
  • Product descriptionN-[(1,2-Dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-indole-3-carboxamide
  • Packaging5mg
  • Price$160
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABKP
  • Product descriptionN-[(1,2-Dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-indole-3-carboxamide
  • Packaging10mg
  • Price$248
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABKP
  • Product descriptionN-[(1,2-Dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-indole-3-carboxamide
  • Packaging25mg
  • Price$403
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABKP
  • Product descriptionN-[(1,2-Dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-indole-3-carboxamide
  • Packaging50mg
  • Price$570
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY229056
  • Product descriptionCPI-360 97.00%
  • Packaging10MG
  • Price$340
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY229056
  • Product descriptionCPI-360 97.00%
  • Packaging50MG
  • Price$820
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number6715DW
  • Product descriptionCID73442743
  • Packaging10mg
  • Price$569
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4836
  • Product descriptionCPI-360
  • Packaging10mg
  • Price$405
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4836
  • Product descriptionCPI-360
  • Packaging5mg
  • Price$249
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4836
  • Product descriptionCPI-360
  • Packaging2mg
  • Price$165
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4836
  • Product descriptionCPI-360
  • Packaging50mg
  • Price$1418
  • Updated2026-05-06
  • Buy
  • ManufacturerArctom
  • Product numberSLK-S7656
  • Product descriptionCPI-360 99.72%
  • Packaging5mg
  • Price$188
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberSLK-S7656
  • Product descriptionCPI-360 99.72%
  • Packaging25mg
  • Price$663
  • Updated2026-05-26
  • Buy
  • ManufacturerBiosynth
  • Product numberCXC17506
  • Product descriptionCPI-360
  • Packaging25mg
  • Price$1429
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberCXC17506
  • Product descriptionCPI-360
  • Packaging50mg
  • Price$1988.5
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00ABKP N-[(1,2-Dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-indole-3-carboxamide ≥98% 1mg $75 2026-05-28 Buy
aablocks AA00ABKP N-[(1,2-Dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-indole-3-carboxamide 5mg $160 2026-05-28 Buy
aablocks AA00ABKP N-[(1,2-Dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-indole-3-carboxamide 10mg $248 2026-05-28 Buy
aablocks AA00ABKP N-[(1,2-Dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-indole-3-carboxamide 25mg $403 2026-05-28 Buy
aablocks AA00ABKP N-[(1,2-Dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-indole-3-carboxamide 50mg $570 2026-05-28 Buy
ACHEMBLOCK Y229056 CPI-360 97.00% 10MG $340 2026-05-27 Buy
ACHEMBLOCK Y229056 CPI-360 97.00% 50MG $820 2026-05-27 Buy
AK Scientific 6715DW CID73442743 10mg $569 2021-12-16 Buy
ApexBio Technology B4836 CPI-360 10mg $405 2026-05-06 Buy
ApexBio Technology B4836 CPI-360 5mg $249 2026-05-06 Buy
ApexBio Technology B4836 CPI-360 2mg $165 2026-05-06 Buy
ApexBio Technology B4836 CPI-360 50mg $1418 2026-05-06 Buy
Arctom SLK-S7656 CPI-360 99.72% 5mg $188 2026-05-26 Buy
Arctom SLK-S7656 CPI-360 99.72% 25mg $663 2026-05-26 Buy
Biosynth CXC17506 CPI-360 25mg $1429 2026-06-04 Buy
Biosynth CXC17506 CPI-360 50mg $1988.5 2026-06-04 Buy
Next Last

Properties

Boiling point :712.2±60.0 °C(Predicted)
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 10 mg/mL; DMSO: 25 mg/mL; Ethanol: 30 mg/mL; Ethanol:PBS (pH7.2) (1:7): 0.12 mg/mL
form :A crystalline solid
pka :11.01±0.10(Predicted)
InChIKey :PFPSFENQCNMITC-MRXNPFEDSA-N
SMILES :N1([C@@H](C2CCOCC2)C)C2=C(C=CC=C2)C(C(NCC2=C(OC)C=C(C)NC2=O)=O)=C1C

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

CPI-360 is a selective EZH2 inhibitor with IC50 values of 0.5 and 2.5 nM for wild-type EZH2 and Y641N mutant EZH2, respectively. It decreases cellular levels of H3K27me3 and H3K27me2 (EC50s = 56 and 65 nM, respectively), triggering cell cycle arrest and ultimately resulting in apoptosis in a large panel of non-Hodgkin’s lymphoma (NHL) cell lines. Twice daily, subcutaneous administration of 200 mg/kg of CPI-360 reduced tumor growth of KARPAS-422 xenografts in mice.

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Suppliers and manufacturers

Zhengzhou convergence chemical co., LTD Haoyuan Chemexpress Co., Ltd. MedChemexpress LLC AdooQ Bioscience CHINA Shanghai Lollane Biological Technology Co.,Ltd. Shanghaizehan biopharma technology co., Ltd. ShangHai Angti Biotechnology Co., Ltd. Guangzhou QiYun Biotechnology Co., Ltd. Shanghai YuanYe Biotechnology Co., Ltd. Shanghai QianYan Bio-technology Co., Ltd