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ChemicalBook >> CAS DataBase List >> CPI-444

CPI-444

CPI-444 price.
  • $10 - $1500
  • Product name: CPI-444
  • CAS: 1202402-40-1
  • MF: C20H21N7O3
  • MW: 407.43
  • EINECS:-0
  • MDL Number:MFCD31540410
  • Synonyms:(S)-7-(5-Methyl-furan-2-yl)-3-[6-(tetrahydro-furan-3-yloxyMethyl)-pyridin-2-ylMethyl]-3H-[1,2,3]triazolo[4,5-d]pyriMidin-5-ylaMine;CPD1110;CPI-444;7-(5-Methyl-2-furanyl)-3-[[6-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]-2-pyridinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine;Triazolo-pyramidine derivative;3H-1,2,3-Triazolo[4,5-d]pyrimidin-5-amine, 7-(5-methyl-2-furanyl)-3-[[6-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]-2-pyridinyl]methyl]-;CPI-444 AND7648;(S)-5-Amino-7-(5-methyl-2-furyl)-3-[[6-[[(3-tetrahydrofuranyl)oxy]methyl]-2-pyridyl]methyl]-3H-[1,2,3]triazolo[4,5-d]pyrimidine
Price41 Properties Safety Information Description
41 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • AvaChem
  • Axon Medchem
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Matrix Scientific
  • TRC
  • Usbiological
Package
  • 10mM*1mLinDMSO
  • 1mg
  • 5mg
  • 10mg
  • 25.00mg
  • 25mg
  • 50mg
  • 50.00mg
  • 100mg
  • 100.00mg
  • 250mg
  • 1G
  • Manufactureraablocks
  • Product numberAA003AEW
  • Product description7-(5-Methyl-2-furanyl)-3-[[6-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]-2-pyridinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine 98%
  • Packaging1mg
  • Price$10
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003AEW
  • Product description7-(5-Methyl-2-furanyl)-3-[[6-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]-2-pyridinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine 98%
  • Packaging5mg
  • Price$21
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003AEW
  • Product description7-(5-Methyl-2-furanyl)-3-[[6-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]-2-pyridinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine 98%
  • Packaging10mg
  • Price$32
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003AEW
  • Product description7-(5-Methyl-2-furanyl)-3-[[6-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]-2-pyridinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine 98%
  • Packaging25mg
  • Price$61
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003AEW
  • Product description7-(5-Methyl-2-furanyl)-3-[[6-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]-2-pyridinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine 98%
  • Packaging50mg
  • Price$100
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003AEW
  • Product description7-(5-Methyl-2-furanyl)-3-[[6-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]-2-pyridinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine 98%
  • Packaging100mg
  • Price$155
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003AEW
  • Product description7-(5-Methyl-2-furanyl)-3-[[6-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]-2-pyridinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine 95%
  • Packaging250mg
  • Price$358
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65455
  • Product description(S)-7-(5-methylfuran-2-yl)-3-((6-(((tetrahydrofuran-3-yl)oxy)methyl)pyridin-2-yl)methyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine 98%
  • Packaging250MG
  • Price$295
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65455
  • Product description(S)-7-(5-methylfuran-2-yl)-3-((6-(((tetrahydrofuran-3-yl)oxy)methyl)pyridin-2-yl)methyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine 98%
  • Packaging100MG
  • Price$195
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65455
  • Product description(S)-7-(5-methylfuran-2-yl)-3-((6-(((tetrahydrofuran-3-yl)oxy)methyl)pyridin-2-yl)methyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine 98%
  • Packaging25MG
  • Price$100
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65455
  • Product description(S)-7-(5-methylfuran-2-yl)-3-((6-(((tetrahydrofuran-3-yl)oxy)methyl)pyridin-2-yl)methyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine 98%
  • Packaging1G
  • Price$750
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number3392DF
  • Product descriptionCiforadenant
  • Packaging1mg
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3392DF
  • Product descriptionCiforadenant
  • Packaging10mg
  • Price$407
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0005711
  • Product description(S)-7-(5-METHYLFURAN-2-YL)-3-((6-(((TETRAHYDROFURAN-3-YL)OXY)METHYL)PYRIDIN-2-YL)METHYL)-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-5-AMINE 95.00%
  • Packaging5MG
  • Price$454.51
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number6229
  • Product descriptionCPI-444 98%
  • Packaging25mg
  • Price$385
  • Updated2026-05-22
  • Buy
  • ManufacturerAvaChem
  • Product number6229
  • Product descriptionCPI-444 98%
  • Packaging5mg
  • Price$95
  • Updated2026-05-22
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA003AEW 7-(5-Methyl-2-furanyl)-3-[[6-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]-2-pyridinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine 98% 1mg $10 2026-05-28 Buy
aablocks AA003AEW 7-(5-Methyl-2-furanyl)-3-[[6-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]-2-pyridinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine 98% 5mg $21 2026-05-28 Buy
aablocks AA003AEW 7-(5-Methyl-2-furanyl)-3-[[6-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]-2-pyridinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine 98% 10mg $32 2026-05-28 Buy
aablocks AA003AEW 7-(5-Methyl-2-furanyl)-3-[[6-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]-2-pyridinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine 98% 25mg $61 2026-05-28 Buy
aablocks AA003AEW 7-(5-Methyl-2-furanyl)-3-[[6-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]-2-pyridinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine 98% 50mg $100 2026-05-28 Buy
aablocks AA003AEW 7-(5-Methyl-2-furanyl)-3-[[6-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]-2-pyridinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine 98% 100mg $155 2026-05-28 Buy
aablocks AA003AEW 7-(5-Methyl-2-furanyl)-3-[[6-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]-2-pyridinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine 95% 250mg $358 2026-05-28 Buy
ACHEMBLOCK Q65455 (S)-7-(5-methylfuran-2-yl)-3-((6-(((tetrahydrofuran-3-yl)oxy)methyl)pyridin-2-yl)methyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine 98% 250MG $295 2026-05-27 Buy
ACHEMBLOCK Q65455 (S)-7-(5-methylfuran-2-yl)-3-((6-(((tetrahydrofuran-3-yl)oxy)methyl)pyridin-2-yl)methyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine 98% 100MG $195 2026-05-27 Buy
ACHEMBLOCK Q65455 (S)-7-(5-methylfuran-2-yl)-3-((6-(((tetrahydrofuran-3-yl)oxy)methyl)pyridin-2-yl)methyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine 98% 25MG $100 2026-05-27 Buy
ACHEMBLOCK Q65455 (S)-7-(5-methylfuran-2-yl)-3-((6-(((tetrahydrofuran-3-yl)oxy)methyl)pyridin-2-yl)methyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine 98% 1G $750 2026-05-27 Buy
AK Scientific 3392DF Ciforadenant 1mg $147 2021-12-16 Buy
AK Scientific 3392DF Ciforadenant 10mg $407 2021-12-16 Buy
American Custom Chemicals Corporation INB0005711 (S)-7-(5-METHYLFURAN-2-YL)-3-((6-(((TETRAHYDROFURAN-3-YL)OXY)METHYL)PYRIDIN-2-YL)METHYL)-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-5-AMINE 95.00% 5MG $454.51 2021-12-16 Buy
AvaChem 6229 CPI-444 98% 25mg $385 2026-05-22 Buy
AvaChem 6229 CPI-444 98% 5mg $95 2026-05-22 Buy
Next Last

Properties

Melting point :169-171°C
Boiling point :676.9±65.0 °C(Predicted)
Density :1.55±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml)
form :solid
pka :4.05±0.30(Predicted)
color :Beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :KURQKNMKCGYWRJ-HNNXBMFYSA-N
SMILES :C1(N)=NC(C2=CC=C(C)O2)=C2N=NN(CC3=NC(CO[C@H]4CCOC4)=CC=C3)C2=N1

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

CPI-444 (1202402-40-1) is a potent (Ki = 3.54 nM) and selective adenosine A2A receptor antagonist. It blocked the induction of cAMP induced by NECA in HEK-293 cells with an IC50 = 17.03 nM. CPI-444 monotherapy or in combination with anti-PD-1, anti-PD-L1, and anti-CTLA-4 induced T-cell-mediated tumor responses, inhibited tumor growth, and enabled antitumor immune memory. Currently in clinical trials for multiple cancers.

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Suppliers and manufacturers

Twochem Co.Ltd. Baimei Jihua (Henan) Pharmaceutical Technology Co., Ltd Anqing YanZhi Pharma Discovery Co.,Ltd. ABBIOCHEM Shanghai Boyle Chemical Co., Ltd. Chembest Research Laboratories Limited Dalian Meilun Biotech Co., Ltd. MedChemexpress LLC ShangHai Caerulum Pharma Discovery Co., Ltd. Shanghai SunSyn Pharmaceutical Co., Ltd.