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ChemicalBook >> CAS DataBase List >> Chloropretadalafil

Chloropretadalafil

Chloropretadalafil price.
  • $6 - $756
  • Product name: Chloropretadalafil
  • CAS: 171489-59-1
  • MF: C22H19ClN2O5
  • MW: 426.85
  • EINECS:
  • MDL Number:MFCD04973633
  • Synonyms:(1R,3R)-Methyl-1,2,3,4-tetrahydro-2-chloroacetyl-1-(3,4-Methylenedioxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate (Chloropretadalafil);(1R,3R)-1-(1,3-benzodioxol-5-yl)-2-(chloroacetyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b] indole-3-carboxylic acid methy ester;1H-Pyrido[3,4-b]indole-3-carboxylic acid, 1-(1,3-benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-, methyl ester, (1R,3R)-;B]indole-3-carboxylate;(1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3;(1R,3R)-1-(1,3-BENZODIOXOL-5-YL)-2-(CHLOROACETYL)-2,3,4,9-TETRAHYDRO-1H-PYRIDO[3,4-B] INDOLE-3-CARBOXYLIC ACID METHYL ESTER;(1R,3R)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester;(1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate
Price38 Properties Safety Information Description
38 prices
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Brand
  • aablocks
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • Crysdot
  • Labseeker
  • Matrix Scientific
  • Synthonix
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 5MG
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  • 25.00g
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  • 500g
  • 500.00g
  • 1kg
  • Manufactureraablocks
  • Product numberAA0077ML
  • Product descriptionMethyl (1R,3R)-1-(1,3-benzodioxol-5-yl)-2-(chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 98%
  • Packaging1g
  • Price$6
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0077ML
  • Product descriptionMethyl (1R,3R)-1-(1,3-benzodioxol-5-yl)-2-(chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 95%
  • Packaging10g
  • Price$23
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0077ML
  • Product descriptionMethyl (1R,3R)-1-(1,3-benzodioxol-5-yl)-2-(chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 95%
  • Packaging25g
  • Price$28
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0077ML
  • Product descriptionMethyl (1R,3R)-1-(1,3-benzodioxol-5-yl)-2-(chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 95%
  • Packaging5g
  • Price$16
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0077ML
  • Product descriptionMethyl (1R,3R)-1-(1,3-benzodioxol-5-yl)-2-(chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 95%
  • Packaging100g
  • Price$95
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0077ML
  • Product descriptionMethyl (1R,3R)-1-(1,3-benzodioxol-5-yl)-2-(chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 98%
  • Packaging500g
  • Price$415
  • Updated2026-05-28
  • Buy
  • ManufacturerAK Scientific
  • Product numberZ2024
  • Product description(1R,3R)-1-Benzo[1,3]dioxol-5-yl-2-(2-chloroethanoyl)2,3,4,9-tetrahydro-1H-b-carboline-3-carboxylicacidmethylester
  • Packaging5g
  • Price$109
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberZ2024
  • Product description(1R,3R)-1-Benzo[1,3]dioxol-5-yl-2-(2-chloroethanoyl)2,3,4,9-tetrahydro-1H-b-carboline-3-carboxylicacidmethylester
  • Packaging10g
  • Price$149
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberZ2024
  • Product description(1R,3R)-1-Benzo[1,3]dioxol-5-yl-2-(2-chloroethanoyl)2,3,4,9-tetrahydro-1H-b-carboline-3-carboxylicacidmethylester
  • Packaging1g
  • Price$71
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA544621
  • Product description(1R,3R)-Methyl1-(benzo[d][1,3]dioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 95%
  • Packaging10g
  • Price$38
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA544621
  • Product description(1R,3R)-Methyl1-(benzo[d][1,3]dioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 95%
  • Packaging1g
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA544621
  • Product description(1R,3R)-Methyl1-(benzo[d][1,3]dioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 95%
  • Packaging5g
  • Price$21
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA544621
  • Product description(1R,3R)-Methyl1-(benzo[d][1,3]dioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 95%
  • Packaging25g
  • Price$74
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA544621
  • Product description(1R,3R)-Methyl1-(benzo[d][1,3]dioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 95%
  • Packaging100g
  • Price$252
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA544621
  • Product description(1R,3R)-Methyl1-(benzo[d][1,3]dioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 95%
  • Packaging500g
  • Price$756
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0028594
  • Product descriptionCHLOROPRETADALAFIL 95.00%
  • Packaging5MG
  • Price$459.06
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0077ML Methyl (1R,3R)-1-(1,3-benzodioxol-5-yl)-2-(chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 98% 1g $6 2026-05-28 Buy
aablocks AA0077ML Methyl (1R,3R)-1-(1,3-benzodioxol-5-yl)-2-(chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 95% 10g $23 2026-05-28 Buy
aablocks AA0077ML Methyl (1R,3R)-1-(1,3-benzodioxol-5-yl)-2-(chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 95% 25g $28 2026-05-28 Buy
aablocks AA0077ML Methyl (1R,3R)-1-(1,3-benzodioxol-5-yl)-2-(chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 95% 5g $16 2026-05-28 Buy
aablocks AA0077ML Methyl (1R,3R)-1-(1,3-benzodioxol-5-yl)-2-(chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 95% 100g $95 2026-05-28 Buy
aablocks AA0077ML Methyl (1R,3R)-1-(1,3-benzodioxol-5-yl)-2-(chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 98% 500g $415 2026-05-28 Buy
AK Scientific Z2024 (1R,3R)-1-Benzo[1,3]dioxol-5-yl-2-(2-chloroethanoyl)2,3,4,9-tetrahydro-1H-b-carboline-3-carboxylicacidmethylester 5g $109 2021-12-16 Buy
AK Scientific Z2024 (1R,3R)-1-Benzo[1,3]dioxol-5-yl-2-(2-chloroethanoyl)2,3,4,9-tetrahydro-1H-b-carboline-3-carboxylicacidmethylester 10g $149 2021-12-16 Buy
AK Scientific Z2024 (1R,3R)-1-Benzo[1,3]dioxol-5-yl-2-(2-chloroethanoyl)2,3,4,9-tetrahydro-1H-b-carboline-3-carboxylicacidmethylester 1g $71 2021-12-16 Buy
Ambeed A544621 (1R,3R)-Methyl1-(benzo[d][1,3]dioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 95% 10g $38 2021-12-16 Buy
Ambeed A544621 (1R,3R)-Methyl1-(benzo[d][1,3]dioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 95% 1g $7 2021-12-16 Buy
Ambeed A544621 (1R,3R)-Methyl1-(benzo[d][1,3]dioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 95% 5g $21 2021-12-16 Buy
Ambeed A544621 (1R,3R)-Methyl1-(benzo[d][1,3]dioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 95% 25g $74 2021-12-16 Buy
Ambeed A544621 (1R,3R)-Methyl1-(benzo[d][1,3]dioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 95% 100g $252 2021-12-16 Buy
Ambeed A544621 (1R,3R)-Methyl1-(benzo[d][1,3]dioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 95% 500g $756 2021-12-16 Buy
American Custom Chemicals Corporation API0028594 CHLOROPRETADALAFIL 95.00% 5MG $459.06 2021-12-16 Buy
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Properties

Melting point :230-232℃
Boiling point :627.5±55.0 °C(Predicted)
Density :1.445
storage temp. :Inert atmosphere,2-8°C
solubility :Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
pka :16.25±0.60(Predicted)
form :Solid
color :White to Pale Orange
InChI :InChI=1S/C22H19ClN2O5/c1-28-22(27)16-9-14-13-4-2-3-5-15(13)24-20(14)21(25(16)19(26)10-23)12-6-7-17-18(8-12)30-11-29-17/h2-8,16,21,24H,9-11H2,1H3/t16-,21-/m1/s1
InChIKey :JUKHNCNDFOAFLT-IIBYNOLFSA-N
SMILES :N1C2=C(C=CC=C2)C2C[C@H](C(OC)=O)N(C(CCl)=O)[C@H](C3=CC=C4OCOC4=C3)C1=2

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

(1R,3R)-1-(1,3-Benzodioxol-5-yl)-2-(chloroacetyl)-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic is used as an intermediate in the synthesis of Tadafil, which is used for the treatment of erectile dysfunction.

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cis-Octahydroisoindole (3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine (1S,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester N-Octyl Nortadalafil (1S,3R)-1-Benzo[1,3]dioxol-5-yl-2-(2-chloro-acetyl)-2,3,4,9-tetrahydro-1H-b-carboline-3-carboxylic Acid Methyl Ester Amino Tadalafil Tadalafil (1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester Tadalafil KetolactaM D(+)-Tryptophan (1S,3S)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester (6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione L-Tryptophan cis-Tadalafil (1R,3S)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester cis-ent-Tadalafil ent-Tadalafil 27738-46-1 7797-83-3 AcetaMinotadalafil

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Suppliers and manufacturers

Jinan Hongwan Biotechnology Co., Ltd. Mianyang Vandino Pharmaceutical Technology Co., Ltd. Shandong Haiwo Biological Technology Co., Ltd. JinanGongchuang Pharmaceutical Technology Co. Ltd.. CHENGHUI PHARMACEUTICAL GROUP LTD Tianjin Chenrui Technology Co., Ltd. Shandong Haiyou Furuida Pharmaceutical Co., Ltd. Jinan Good Medical &Technology Ltd Co., J & K SCIENTIFIC LTD. 3B Pharmachem (Wuhan) International Co.,Ltd.