Ciclesonide
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- $32 - $1617
- Product name: Ciclesonide
- CAS: 126544-47-6
- MF: C32H44O7
- MW: 540.69
- EINECS:
- MDL Number:MFCD00866004
- Synonyms:(r)-11b,16a,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with cyclohexanecarboxaldehyde 21-isobutyrate;Ciclesonide;(11β,16α)-16,17-[[(R)-CyclohexylMethylene]bis(oxy)]-11-hydroxy-21-(2-Methyl-1-oxopropoxy)-pregna-1,4-diene-3,20-dione;Ciclesonide(RPR251526);Ciclesonide containing impurity A CRS;Ciclesonide CRS;Zetonna;Pregna-1,4-diene-3,20-dione, 16,17-[[(R)-cyclohexylmethylene]bis(oxy)]-11-hydroxy-21-(2-methyl-1-oxopropoxy)-, (11β,16α)-
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Brand
- AHH
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- AvaChem
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Chemtos
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
Package
- 5mg
- y0001553
- 1mg
- 10mg
- 25mg
- 25
- 5
- 50mg
- 100mg
- 0.1g
- 1G
- ManufacturerAHH
- Product numberMT-49256
- Product descriptionCiclesonide 98%
- Packaging0.1g
- Price$410
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberO945
- Product descriptionCiclesonide
- Packaging100mg
- Price$616
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0002005
- Product descriptionCICLESONIDE 95.00%
- Packaging1G
- Price$1617
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3477
- Product descriptionCiclesonide
- Packaging10mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3477
- Product descriptionCiclesonide
- Packaging50mg
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2479
- Product descriptionCiclesonide
- Packaging5mg
- Price$49
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2479
- Product descriptionCiclesonide
- Packaging10mg
- Price$69
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2479
- Product descriptionCiclesonide
- Packaging25mg
- Price$119
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2479
- Product descriptionCiclesonide
- Packaging100mg
- Price$179
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2479
- Product descriptionCiclesonide
- Packaging1g
- Price$529
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC20428
- Product descriptionCiclesonide
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC20428
- Product descriptionCiclesonide
- Packaging50mg
- Price$262.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18227
- Product descriptionCiclesonide ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18227
- Product descriptionCiclesonide ≥98%
- Packaging5mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18227
- Product descriptionCiclesonide ≥98%
- Packaging10mg
- Price$184
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18227
- Product descriptionCiclesonide ≥98%
- Packaging50mg
- Price$759
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AHH | MT-49256 | Ciclesonide 98% | 0.1g | $410 | 2021-12-16 | Buy |
AK Scientific | O945 | Ciclesonide | 100mg | $616 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0002005 | CICLESONIDE 95.00% | 1G | $1617 | 2021-12-16 | Buy |
ApexBio Technology | B3477 | Ciclesonide | 10mg | $70 | 2021-12-16 | Buy |
ApexBio Technology | B3477 | Ciclesonide | 50mg | $300 | 2021-12-16 | Buy |
AvaChem | 2479 | Ciclesonide | 5mg | $49 | 2021-12-16 | Buy |
AvaChem | 2479 | Ciclesonide | 10mg | $69 | 2021-12-16 | Buy |
AvaChem | 2479 | Ciclesonide | 25mg | $119 | 2021-12-16 | Buy |
AvaChem | 2479 | Ciclesonide | 100mg | $179 | 2021-12-16 | Buy |
AvaChem | 2479 | Ciclesonide | 1g | $529 | 2021-12-16 | Buy |
Biosynth Carbosynth | FC20428 | Ciclesonide | 10mg | $75 | 2021-12-16 | Buy |
Biosynth Carbosynth | FC20428 | Ciclesonide | 50mg | $262.5 | 2021-12-16 | Buy |
Cayman Chemical | 18227 | Ciclesonide ≥98% | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 18227 | Ciclesonide ≥98% | 5mg | $109 | 2024-03-01 | Buy |
Cayman Chemical | 18227 | Ciclesonide ≥98% | 10mg | $184 | 2024-03-01 | Buy |
Cayman Chemical | 18227 | Ciclesonide ≥98% | 50mg | $759 | 2024-03-01 | Buy |
Properties
Melting point :202-209?C
Boiling point :665.0±55.0 °C(Predicted)
Density :1.23±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :Chlorofrom (Slightly), Methanol (Slightly)
form :Solid
pka :14.25±0.70(Predicted)
color :White to Off-White
biological source :synthetic
Water Solubility :water: <0.1g/L
acetone: soluble
ethanol: soluble InChIKey :LUKZNWIVRBCLON-GXOBDPJESA-N
SMILES :[C@@]12(C(=O)COC(=O)C(C)C)O[C@H](C3CCCCC3)O[C@@H]1C[C@@]1([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3([H])[C@@H](O)C[C@]21C |&1:0,11,19,21,23,33,35,37,40,r|
Boiling point :665.0±55.0 °C(Predicted)
Density :1.23±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :Chlorofrom (Slightly), Methanol (Slightly)
form :Solid
pka :14.25±0.70(Predicted)
color :White to Off-White
biological source :synthetic
Water Solubility :water: <0.1g/L
acetone: soluble
ethanol: soluble InChIKey :LUKZNWIVRBCLON-GXOBDPJESA-N
SMILES :[C@@]12(C(=O)COC(=O)C(C)C)O[C@H](C3CCCCC3)O[C@@H]1C[C@@]1([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3([H])[C@@H](O)C[C@]21C |&1:0,11,19,21,23,33,35,37,40,r|
Safety Information
Symbol(GHS): |
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Signal word: | Warning | ||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
Ciclesonide (CIC) is a corticosteroid prodrug that is converted to its active form, desisobutyryl-CIC (des-CIC), by cellular esterases. Des-CIC is a glucocorticoid receptor agonist (Ki = 0.31 nM). Inhaled corticosteroids, including CIC, are used to ameliorate symptoms of airway inflammatory diseases, such as asthma, allergic rhinitis, and chronic obstructive pulmonary disease.Related product price
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