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ChemicalBook >> CAS DataBase List >> Disulfiram

Disulfiram

Disulfiram price.
  • $13.44 - $1504.5
  • Product name: Disulfiram
  • CAS: 97-77-8
  • MF: C10H20N2S4
  • MW: 296.54
  • EINECS:202-607-8
  • MDL Number:MFCD00009048
  • Synonyms:Tillram;TTS x;Tuads, ethyl;1,1’-dithiobis(n,n-diethylthio-formamid ;1,1’-dithiobis(n,n-diethylthioformamide) ;1,1'-Dithiobis(N,N-diethylthioformamide);Abstenisil ;Abstensil
Price42 Properties Safety Information Description
42 prices
Selected condition：
Brand
  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • Aronis compounds
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • Frontier Specialty Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
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  • 25g
  • d2950000
  • 200mg
  • 100g
  • 250g
  • 500g
  • 1000g
  • 1kg
  • 5000g
  • 1GT
  • ManufacturerAK Scientific
  • Product numberJ53113
  • Product descriptionDisulfiram
  • Packaging25g
  • Price$20
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberB20721
  • Product descriptionTetraethylthiuram disulfide, 97%
  • Packaging250g
  • Price$40.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberB20721
  • Product descriptionTetraethylthiuram disulfide, 97%
  • Packaging1000g
  • Price$109.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberB20721
  • Product descriptionTetraethylthiuram disulfide, 97%
  • Packaging5000g
  • Price$406.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002428
  • Product descriptionTETRAETHYLTHIURAM DISULFIDE 95.00%
  • Packaging5MG
  • Price$521
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002428
  • Product descriptionTETRAETHYLTHIURAM DISULFIDE 95.00%
  • Packaging1GT
  • Price$1290.15
  • Updated2021-12-16
  • Buy
  • ManufacturerAronis compounds
  • Product numberBBC/257
  • Product description1,1',1'',1'''-{disulfanediylbis[(thioxomethylene)nitrilo]}tetraethane
  • Packaging1g
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb134703
  • Product descriptionDisulfiram (Antabuse) >99%
  • Packaging100mg
  • Price$510
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb134703
  • Product descriptionDisulfiram (Antabuse) >99%
  • Packaging250mg
  • Price$765
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb134703
  • Product descriptionDisulfiram (Antabuse) >99%
  • Packaging1g
  • Price$1504.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD22545
  • Product descriptionDisulfiram
  • Packaging100g
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD22545
  • Product descriptionDisulfiram
  • Packaging250g
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD22545
  • Product descriptionDisulfiram
  • Packaging500g
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD22545
  • Product descriptionDisulfiram
  • Packaging1kg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15303
  • Product descriptionDisulfiram ≥95%
  • Packaging50g
  • Price$30
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15303
  • Product descriptionDisulfiram ≥95%
  • Packaging100g
  • Price$44
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J53113 Disulfiram 25g $20 2021-12-16 Buy
Alfa Aesar B20721 Tetraethylthiuram disulfide, 97% 250g $40.65 2024-03-01 Buy
Alfa Aesar B20721 Tetraethylthiuram disulfide, 97% 1000g $109.65 2024-03-01 Buy
Alfa Aesar B20721 Tetraethylthiuram disulfide, 97% 5000g $406.65 2024-03-01 Buy
American Custom Chemicals Corporation API0002428 TETRAETHYLTHIURAM DISULFIDE 95.00% 5MG $521 2021-12-16 Buy
American Custom Chemicals Corporation API0002428 TETRAETHYLTHIURAM DISULFIDE 95.00% 1GT $1290.15 2021-12-16 Buy
Aronis compounds BBC/257 1,1',1'',1'''-{disulfanediylbis[(thioxomethylene)nitrilo]}tetraethane 1g $133 2021-12-16 Buy
Biorbyt Ltd orb134703 Disulfiram (Antabuse) >99% 100mg $510 2021-12-16 Buy
Biorbyt Ltd orb134703 Disulfiram (Antabuse) >99% 250mg $765 2021-12-16 Buy
Biorbyt Ltd orb134703 Disulfiram (Antabuse) >99% 1g $1504.5 2021-12-16 Buy
Biosynth Carbosynth FD22545 Disulfiram 100g $75 2021-12-16 Buy
Biosynth Carbosynth FD22545 Disulfiram 250g $125 2021-12-16 Buy
Biosynth Carbosynth FD22545 Disulfiram 500g $160 2021-12-16 Buy
Biosynth Carbosynth FD22545 Disulfiram 1kg $200 2021-12-16 Buy
Cayman Chemical 15303 Disulfiram ≥95% 50g $30 2024-03-01 Buy
Cayman Chemical 15303 Disulfiram ≥95% 100g $44 2024-03-01 Buy
Next Last

Properties

Melting point :69-71 °C (lit.)
Boiling point :117°C
Density :1.27
vapor pressure :0Pa at 25℃
refractive index :1.5500 (estimate)
Flash point :117°C/17mm
storage temp. :2-8°C
solubility :0.004g/l
pka :0.86±0.50(Predicted)
form :Crystals, Crystalline Powder or Granules
color :Light yellow
Odor :lt. gray powd., sl. odor
Water Solubility :0.02 g/100 mL
Merck :14,3364
BRN :1712560
Exposure limits :ACGIH: TWA 2 mg/m3
NIOSH: TWA 2 mg/m3 Stability :Stable. Incompatible with strong oxidants.
InChIKey :AUZONCFQVSMFAP-UHFFFAOYSA-N
LogP :3.6 at 21℃
CAS DataBase Reference :97-77-8(CAS DataBase Reference)
IARC :3 (Vol. 12, Sup 7) 1987
NIST Chemistry Reference :Disulfiram(97-77-8)
EPA Substance Registry System :Disulfiram (97-77-8)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P314 Get medical advice/attention if you feel unwell.

Description

Disulfiram is a copper and zinc chelator and an irreversible inhibitor of aldehyde dehydrogenase (IC50 = 0.1 mM) that has been indicated for the treatment of alcohol dependence. It also inhibits the copper-dependent enzyme dopamine β-hydroxylase, which prevents the breakdown of dopamine and has been considered as a treatment for cocaine dependence. When in complex with copper, disulfiram has been shown to inhibit purified 20S proteasome (IC50 = 7.5 μM) and 26S proteasome (IC50 = 20 μM) from MDA-MB-0231 breast cancer cells. Because disulfiram targets the ubiquitin-proteasome pathway, it has been investigated as an anti-cancer agent. Furthermore, at 250 nM it has been shown to induce reactive oxygen species, to activate JNK and p38 pathways, and to inhibit NF-κB activity, which suppresses self-renewal in cancer stem cells.

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Suppliers and manufacturers

Hebei Mojin Biotechnology Co., Ltd
Disulfiram
$0.00 /25KG
Disulfiram CAS:97-77-8
Hebei Yanxi Chemical Co., Ltd.
Disulfiram
$10.00 /1000kg
Disulfiram CAS:97-77-8
Chemson Industrial (Shanghai) Co., Ltd.
Accelerator TETD; Disulfiram; Tetraethylthiuramdisulfide
$4.00 /25KG
Accelerator TETD; Disulfiram; Tetraethylthiuramdisulfide CAS:97-77-8
career henan chemical co
Disulfiram
$100.00 /1KG
Disulfiram CAS:97-77-8
Hebei Guanlang Biotechnology Co., Ltd.
Disulfiram
$10.00 /1KG
Disulfiram CAS:97-77-8
Henan Xiangtong Chemical Co., Ltd.
Rubber Accelerator TETD
$1.00 /1KG
Rubber Accelerator TETD CAS:97-77-8
Henan Tianfu Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.
Biochempartner
Hubei Jusheng Technology Co.,Ltd.