E-64C
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- $32 - $1800
- Product name: E-64C
- CAS: 76684-89-4
- MF: C15H26N2O5
- MW: 314.38
- EINECS:
- MDL Number:MFCD00132882
- Synonyms:(2S,3S)-TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-3-METHYLBUTANE;(2S,3S)-L-TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-3-METHYLBUTANE;(2S,3S)-3-(((S)-1-(isopentylaMino)-4-Methyl-1-oxopentan-2-yl)carbaMoyl)oxirane-2-carboxylic acid;2-Oxiranecarboxylicacid,3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-,(2S,3S)-;Loxistatin Acid (E-64C);NSC 694279;E-64c, EP 475;(1S,2S)-2-(((S)-1-(Isopentylamino)-4-methyl-1-oxopentan-2-yl)carbamoyl)cyclopropanecarboxylic
78 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- Biosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- TRC
- Usbiological
Package
- 10mM(in1mLDMSO)
- 1mg
- 5mg
- 10mM(in 1mL DMSO)
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 5.00g
- 10.00g
- 25.00g
- Manufactureraablocks
- Product numberAA00G32H
- Product descriptionLoxistatin acid ≥98%
- Packaging1mg
- Price$32
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00G32H
- Product descriptionLoxistatin acid
- Packaging5mg
- Price$71
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00G32H
- Product descriptionLoxistatin acid
- Packaging10mg
- Price$106
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00G32H
- Product descriptionLoxistatin acid
- Packaging25mg
- Price$163
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00G32H
- Product descriptionLoxistatin acid
- Packaging50mg
- Price$239
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00G32H
- Product descriptionLoxistatin acid
- Packaging100mg
- Price$335
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228836
- Product descriptionE 64c 97.00%
- Packaging100MG
- Price$470
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228836
- Product descriptionE 64c 97.00%
- Packaging25MG
- Price$210
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CP3-7007-M005
- Product descriptionLoxistatin acid [E-64c] ≥98%(HPLC)
- Packaging5mg
- Price$240
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CP3-7007-M001
- Product descriptionLoxistatin acid [E-64c] ≥98%(HPLC)
- Packaging1mg
- Price$60
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product number2390AH
- Product descriptionLoxistatinacid
- Packaging25mg
- Price$1258
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA602643
- Product descriptionE 64c 95%
- Packaging250mg
- Price$645
- Updated2026-06-05
- Buy
- ManufacturerAmbeed
- Product numberA602643
- Product descriptionE 64c 95%
- Packaging50mg
- Price$369
- Updated2026-06-05
- Buy
- ManufacturerAmbeed
- Product numberA602643
- Product descriptionE 64c 95%
- Packaging100mg
- Price$443
- Updated2026-06-05
- Buy
- ManufacturerAmbeed
- Product numberA602643
- Product descriptionE 64c 95%
- Packaging25mg
- Price$271
- Updated2026-06-05
- Buy
- ManufacturerAmbeed
- Product numberA602643
- Product descriptionE 64c 95%
- Packaging5mg
- Price$95
- Updated2026-06-05
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00G32H | Loxistatin acid ≥98% | 1mg | $32 | 2026-05-28 | Buy |
| aablocks | AA00G32H | Loxistatin acid | 5mg | $71 | 2026-05-28 | Buy |
| aablocks | AA00G32H | Loxistatin acid | 10mg | $106 | 2026-05-28 | Buy |
| aablocks | AA00G32H | Loxistatin acid | 25mg | $163 | 2026-05-28 | Buy |
| aablocks | AA00G32H | Loxistatin acid | 50mg | $239 | 2026-05-28 | Buy |
| aablocks | AA00G32H | Loxistatin acid | 100mg | $335 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y228836 | E 64c 97.00% | 100MG | $470 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y228836 | E 64c 97.00% | 25MG | $210 | 2026-05-27 | Buy |
| Adipogen Life Sciences | AG-CP3-7007-M005 | Loxistatin acid [E-64c] ≥98%(HPLC) | 5mg | $240 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CP3-7007-M001 | Loxistatin acid [E-64c] ≥98%(HPLC) | 1mg | $60 | 2026-05-06 | Buy |
| AK Scientific | 2390AH | Loxistatinacid | 25mg | $1258 | 2021-12-16 | Buy |
| Ambeed | A602643 | E 64c 95% | 250mg | $645 | 2026-06-05 | Buy |
| Ambeed | A602643 | E 64c 95% | 50mg | $369 | 2026-06-05 | Buy |
| Ambeed | A602643 | E 64c 95% | 100mg | $443 | 2026-06-05 | Buy |
| Ambeed | A602643 | E 64c 95% | 25mg | $271 | 2026-06-05 | Buy |
| Ambeed | A602643 | E 64c 95% | 5mg | $95 | 2026-06-05 | Buy |
Properties
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :≥31.4 mg/mL in DMSO; insoluble in H2O; ≥111.8 mg/mL in EtOH
form :White to off-white solid
color :White to off-white
biological source :synthetic (organic)
InChI :InChI=1S/C15H26N2O5/c1-8(2)5-6-16-13(18)10(7-9(3)4)17-14(19)11-12(22-11)15(20)21/h8-12H,5-7H2,1-4H3,(H,16,18)(H,17,19)(H,20,21)/t10-,11-,12-/m0/s1
InChIKey :SCMSYZJDIQPSDI-SRVKXCTJSA-N
SMILES :O1[C@H](C(N[C@H](C(NCCC(C)C)=O)CC(C)C)=O)[C@H]1C(O)=O
solubility :≥31.4 mg/mL in DMSO; insoluble in H2O; ≥111.8 mg/mL in EtOH
form :White to off-white solid
color :White to off-white
biological source :synthetic (organic)
InChI :InChI=1S/C15H26N2O5/c1-8(2)5-6-16-13(18)10(7-9(3)4)17-14(19)11-12(22-11)15(20)21/h8-12H,5-7H2,1-4H3,(H,16,18)(H,17,19)(H,20,21)/t10-,11-,12-/m0/s1
InChIKey :SCMSYZJDIQPSDI-SRVKXCTJSA-N
SMILES :O1[C@H](C(N[C@H](C(NCCC(C)C)=O)CC(C)C)=O)[C@H]1C(O)=O
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
E-64c is an active metabolite of the protease inhibitor E-64d . E-64c inhibits the cysteine proteases cathepsin B, cathepsin H, and papain but not the serine proteases trypsin, chymotrypsin, or elastase. It reduces the autocatalytic activity of the foot-and-mouth-disease virus (FMDV) leader protease when used at concentrations ranging from 0.1 to 1 mg/ml. E-64c reduces infection of HEK293T cells by an HIV-based virus system pseudotyped with severe acute respiratory syndrome coronavirus (SARS-CoV) surface glycoprotein, also known as the spike glycoprotein, in a concentration-dependent manner.Related product price
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