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ChemicalBook >> CAS DataBase List >> E-7046

E-7046

E-7046 price.
  • $12 - $2187
  • Product name: E-7046
  • CAS: 1369489-71-3
  • MF: C22H18F5N3O4
  • MW: 483.39
  • EINECS:
  • MDL Number:MFCD30502665
  • Synonyms:E-7046;(S)-4-(1-(3-(difluoromethyl)-1-methyl-5-(3-(trifluoromethyl)phenoxy)-1H-pyrazole-4-carboxamido)ethyl)benzoic acid;E-7046,E7046;ER-886046-00;AN-0025;E-7046;E 7046;E7046;Benzoic acid, 4-[(1S)-1-[[[3-(difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]-1H-pyrazol-4-yl]carbonyl]amino]ethyl]-;CPD1542
Price43 Properties Safety Information Description
43 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Matrix Scientific
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 2.5mg
  • 10mM*1mLinDMSO
  • 10mg
  • 10.00mg
  • 25.00mg
  • 25mg
  • 50.00mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 5g
  • Manufactureraablocks
  • Product numberAA019G97
  • Product description4-[(1S)-1-[[[3-(Difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]-1H-pyrazol-4-yl]carbonyl]amino]ethyl]benzoic acid 99%
  • Packaging25mg
  • Price$87
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA019G97
  • Product description4-[(1S)-1-[[[3-(Difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]-1H-pyrazol-4-yl]carbonyl]amino]ethyl]benzoic acid 98%
  • Packaging100mg
  • Price$140
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA019G97
  • Product description4-[(1S)-1-[[[3-(Difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]-1H-pyrazol-4-yl]carbonyl]amino]ethyl]benzoic acid 98%
  • Packaging250mg
  • Price$207
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA019G97
  • Product description4-[(1S)-1-[[[3-(Difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]-1H-pyrazol-4-yl]carbonyl]amino]ethyl]benzoic acid 98%
  • Packaging1g
  • Price$507
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA019G97
  • Product description4-[(1S)-1-[[[3-(Difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]-1H-pyrazol-4-yl]carbonyl]amino]ethyl]benzoic acid 98%
  • Packaging5g
  • Price$1508
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA019G97
  • Product description4-[(1S)-1-[[[3-(Difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]-1H-pyrazol-4-yl]carbonyl]amino]ethyl]benzoic acid 99%
  • Packaging10mg
  • Price$45
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA019G97
  • Product description4-[(1S)-1-[[[3-(Difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]-1H-pyrazol-4-yl]carbonyl]amino]ethyl]benzoic acid 99%
  • Packaging5mg
  • Price$29
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA019G97
  • Product description4-[(1S)-1-[[[3-(Difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]-1H-pyrazol-4-yl]carbonyl]amino]ethyl]benzoic acid 99%
  • Packaging1mg
  • Price$12
  • Updated2026-05-29
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15690
  • Product descriptionE-7046 98%
  • Packaging250MG
  • Price$417
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15690
  • Product descriptionE-7046 98%
  • Packaging100MG
  • Price$208
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15690
  • Product descriptionE-7046 98%
  • Packaging25MG
  • Price$77
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number1890DN
  • Product descriptionCID56944705
  • Packaging25mg
  • Price$195
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1890DN
  • Product descriptionCID56944705
  • Packaging250mg
  • Price$946
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1890DN
  • Product descriptionCID56944705
  • Packaging1g
  • Price$2187
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA368414
  • Product description(S)-4-(1-(3-(Difluoromethyl)-1-methyl-5-(3-(trifluoromethyl)phenoxy)-1H-pyrazole-4-carboxamido)ethyl)benzoicacid 99+%
  • Packaging10mg
  • Price$54
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA368414
  • Product description(S)-4-(1-(3-(Difluoromethyl)-1-methyl-5-(3-(trifluoromethyl)phenoxy)-1H-pyrazole-4-carboxamido)ethyl)benzoicacid 99+%
  • Packaging5mg
  • Price$38
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA019G97 4-[(1S)-1-[[[3-(Difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]-1H-pyrazol-4-yl]carbonyl]amino]ethyl]benzoic acid 99% 25mg $87 2026-05-29 Buy
aablocks AA019G97 4-[(1S)-1-[[[3-(Difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]-1H-pyrazol-4-yl]carbonyl]amino]ethyl]benzoic acid 98% 100mg $140 2026-05-29 Buy
aablocks AA019G97 4-[(1S)-1-[[[3-(Difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]-1H-pyrazol-4-yl]carbonyl]amino]ethyl]benzoic acid 98% 250mg $207 2026-05-29 Buy
aablocks AA019G97 4-[(1S)-1-[[[3-(Difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]-1H-pyrazol-4-yl]carbonyl]amino]ethyl]benzoic acid 98% 1g $507 2026-05-29 Buy
aablocks AA019G97 4-[(1S)-1-[[[3-(Difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]-1H-pyrazol-4-yl]carbonyl]amino]ethyl]benzoic acid 98% 5g $1508 2026-05-29 Buy
aablocks AA019G97 4-[(1S)-1-[[[3-(Difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]-1H-pyrazol-4-yl]carbonyl]amino]ethyl]benzoic acid 99% 10mg $45 2026-05-29 Buy
aablocks AA019G97 4-[(1S)-1-[[[3-(Difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]-1H-pyrazol-4-yl]carbonyl]amino]ethyl]benzoic acid 99% 5mg $29 2026-05-29 Buy
aablocks AA019G97 4-[(1S)-1-[[[3-(Difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]-1H-pyrazol-4-yl]carbonyl]amino]ethyl]benzoic acid 99% 1mg $12 2026-05-29 Buy
ACHEMBLOCK M15690 E-7046 98% 250MG $417 2026-05-27 Buy
ACHEMBLOCK M15690 E-7046 98% 100MG $208 2026-05-27 Buy
ACHEMBLOCK M15690 E-7046 98% 25MG $77 2026-05-27 Buy
AK Scientific 1890DN CID56944705 25mg $195 2021-12-16 Buy
AK Scientific 1890DN CID56944705 250mg $946 2021-12-16 Buy
AK Scientific 1890DN CID56944705 1g $2187 2021-12-16 Buy
Ambeed A368414 (S)-4-(1-(3-(Difluoromethyl)-1-methyl-5-(3-(trifluoromethyl)phenoxy)-1H-pyrazole-4-carboxamido)ethyl)benzoicacid 99+% 10mg $54 2021-12-16 Buy
Ambeed A368414 (S)-4-(1-(3-(Difluoromethyl)-1-methyl-5-(3-(trifluoromethyl)phenoxy)-1H-pyrazole-4-carboxamido)ethyl)benzoicacid 99+% 5mg $38 2021-12-16 Buy
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Properties

Boiling point :594.8±50.0 °C(Predicted)
Density :1.43±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :≤12mg/ml in ethanol;14mg/ml in DMSO;2mg/ml in dimethyl formamide
form :crystalline solid
pka :4.17±0.10(Predicted)
color :White to off-white
InChIKey :MKLKAQMPKHNQPR-NSHDSACASA-N
SMILES :C(O)(=O)C1=CC=C([C@@H](NC(C2=C(OC3=CC=CC(C(F)(F)F)=C3)N(C)N=C2C(F)F)=O)C)C=C1

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

E-7046 is an orally bioavailable and specific EP4 antagonist and exhibits anti-tumor activity. EP4 antagonists reverse PGE2-induced suppression of TNFα production in human whole blood.

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Suppliers and manufacturers

Twochem Co.Ltd ShangHai Caerulum Pharma Discovery Co., Ltd. Shanghai Boyle Chemical Co., Ltd. Chembest Research Laboratories Limited WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. MedChemexpress LLC Shanghai Lollane Biological Technology Co.,Ltd. Shanghaizehan biopharma technology co., Ltd. Guangzhou Zhiya Chemdrugs Co.,Ltd Shanghai YuanYe Biotechnology Co., Ltd.