ECHINOCYSTIC ACID
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- $48 - $1933
- Product name: ECHINOCYSTIC ACID
- CAS: 510-30-5
- MF: C30H48O4
- MW: 472.7
- EINECS:208-112-3
- MDL Number:MFCD00017295
- Synonyms:ECHINOCYSTIC ACID;3-B,16-A-DIHYDROXYOLEAN-12-EN-28-OIC ACID;3BETA,16ALPHA-DIHYDROXY-OLEAN-12-EN-28-OIC ACID;(3beta,16alpha)-3,16-dihydroxyolean-12-en-28-oic acid;Echinocystic;ECHINOCYSTIC ACID(SH);ECHINOCYSTIC ACID hplc;(4aR,5R,6aR,6aS,6bR,8aR,10S,12aR,14bS)-5,10-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
32 prices
Selected condition：
Brand
- AHH
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 20mg
- 25mg
- 0.05g
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAHH
- Product numberMT-50764
- Product descriptionEchinocysticacid 98%
- Packaging0.05g
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberW2530
- Product descriptionEchinocysticacid
- Packaging1mg
- Price$49
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA446246
- Product description(4aR,5R,6aS,6bR,8aR,10S,12aR,12bR,14bS)-5,10-Dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylicacid 97%
- Packaging5mg
- Price$48
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA446246
- Product description(4aR,5R,6aS,6bR,8aR,10S,12aR,12bR,14bS)-5,10-Dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylicacid 97%
- Packaging10mg
- Price$71
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA446246
- Product description(4aR,5R,6aS,6bR,8aR,10S,12aR,12bR,14bS)-5,10-Dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylicacid 97%
- Packaging100mg
- Price$344
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0029408
- Product descriptionECHINOCYSTIC ACID 95.00%
- Packaging10MG
- Price$825.89
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN2178
- Product descriptionEchinocysticacid
- Packaging20mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN98812
- Product descriptionEchinocysticacid ≥98%
- Packaging20mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberSY075933
- Product descriptionEchinocysticacid,98%,fromHederaLinn.
- Packaging10mg
- Price$84.55
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2692
- Product descriptionEchinocystic Acid
- Packaging5mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2692
- Product descriptionEchinocystic Acid
- Packaging10mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2692
- Product descriptionEchinocystic Acid
- Packaging25mg
- Price$195
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2692
- Product descriptionEchinocystic Acid
- Packaging100mg
- Price$495
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb593902
- Product descriptionEchinocystic acid
- Packaging20mg
- Price$221
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb593902
- Product descriptionEchinocystic acid
- Packaging100mg
- Price$372.3
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFE65561
- Product descriptionEchinocystic acid
- Packaging5mg
- Price$50
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | MT-50764 | Echinocysticacid 98% | 0.05g | $280 | 2021-12-16 | Buy |
| AK Scientific | W2530 | Echinocysticacid | 1mg | $49 | 2021-12-16 | Buy |
| Ambeed | A446246 | (4aR,5R,6aS,6bR,8aR,10S,12aR,12bR,14bS)-5,10-Dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylicacid 97% | 5mg | $48 | 2021-12-16 | Buy |
| Ambeed | A446246 | (4aR,5R,6aS,6bR,8aR,10S,12aR,12bR,14bS)-5,10-Dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylicacid 97% | 10mg | $71 | 2021-12-16 | Buy |
| Ambeed | A446246 | (4aR,5R,6aS,6bR,8aR,10S,12aR,12bR,14bS)-5,10-Dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylicacid 97% | 100mg | $344 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0029408 | ECHINOCYSTIC ACID 95.00% | 10MG | $825.89 | 2021-12-16 | Buy |
| ApexBio Technology | N2178 | Echinocysticacid | 20mg | $200 | 2021-12-16 | Buy |
| Arctom | CFN98812 | Echinocysticacid ≥98% | 20mg | $60 | 2021-12-16 | Buy |
| Arctom | SY075933 | Echinocysticacid,98%,fromHederaLinn. | 10mg | $84.55 | 2021-12-16 | Buy |
| AvaChem | 2692 | Echinocystic Acid | 5mg | $65 | 2021-12-16 | Buy |
| AvaChem | 2692 | Echinocystic Acid | 10mg | $95 | 2021-12-16 | Buy |
| AvaChem | 2692 | Echinocystic Acid | 25mg | $195 | 2021-12-16 | Buy |
| AvaChem | 2692 | Echinocystic Acid | 100mg | $495 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb593902 | Echinocystic acid | 20mg | $221 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb593902 | Echinocystic acid | 100mg | $372.3 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FE65561 | Echinocystic acid | 5mg | $50 | 2021-12-16 | Buy |
Properties
Melting point :299-300°C
Boiling point :585.0±50.0 °C(Predicted)
Density :1.14
storage temp. :2-8°C
solubility :DMF:30.0(Max Conc. mg/mL);63.46(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:2):0.33(Max Conc. mg/mL);0.7(Max Conc. mM) form :powder
pka :4.43±0.70(Predicted)
color :White
LogP :7.580 (est)
Boiling point :585.0±50.0 °C(Predicted)
Density :1.14
storage temp. :2-8°C
solubility :DMF:30.0(Max Conc. mg/mL);63.46(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:2):0.33(Max Conc. mg/mL);0.7(Max Conc. mM) form :powder
pka :4.43±0.70(Predicted)
color :White
LogP :7.580 (est)
Safety Information
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Description
Echinocystic acid is a triterpene that has been found in G. sinensis and has diverse biological activities. It induces nuclear translocation of the glucocorticoid receptor (GR) and reduces TNF-α-induced NF-κB signaling in HEK293 cells overexpressing GFP-GR. Echinocystic acid (12.5, 25, and 50 μM) suppresses RANKL-induced NF-κB activation, ERK phosphorylation, and osteoclastogenesis in mouse bone marrow macrophages (BMMs). It induces neurite outgrowth in Neuro2A cells in a concentration-dependent manner, an effect that can be blocked by the JNK inhibitor SP 600125 . In vivo, echinocystic acid (10 mg/kg per day) decreases escape latency in the Morris water maze and increases the length of neurite processes in the hippocampus of aged mice. Topical administration of echinocystic acid reduces expression of COX-2, inducible nitric oxide synthase (iNOS), TNF-α, and IL-1β and ear edema induced by phorbol 12-myristate 13-acetate (TPA; ) in a mouse model of dermatitis. Echinocystic acid also recovers reductions in femoral bone mineral density and trabecular thickness and number in a rat model of ovariectomy-induced osteoporosis.More related product prices
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Suppliers and manufacturers
Shanghai Daken Advanced Materials Co.,Ltd
Shanghai Zheyan Biotech Co., Ltd.
Chengdu GLP biotechnology Co Ltd
Chengdu Biopurify Phytochemicals Ltd.
Hubei Jusheng Technology Co.,Ltd.
Shaanxi Pioneer Biotech Co., Ltd .
