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ChemicalBook >> CAS DataBase List >> EED226

EED226

EED226 price.
  • $37 - $892
  • Product name: EED226
  • CAS: 2083627-02-3
  • MF: C17H15N5O3S
  • MW: 369.4
  • EINECS:-0
  • MDL Number:MFCD30738018
  • Synonyms:EED226;N-(furan-2-ylmethyl)-8-(4-(methylsulfonyl)phenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine;MAK683(EED226/Compound 43);CS-2549;EED226;EED 226;EED226;EED 226;MAK683;1,2,4-Triazolo[4,3-c]pyrimidin-5-amine, N-(2-furanylmethyl)-8-[4-(methylsulfonyl)phenyl]-;N-[(furan-2-yl)methyl]-8-(4-methanesulfonylphenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine
21 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Axon Medchem
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number3723EH
  • Product descriptionN-(Furan-2-Ylmethyl)-8-(4-Methylsulfonylphenyl)-[1,2,4]triazolo[4,3-C]pyrimidin-5-Amine
  • Packaging10mg
  • Price$413
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0005706
  • Product descriptionN-(FURAN-2-YLMETHYL)-8-(4-(METHYLSULFONYL)PHENYL)-[1,2,4]TRIAZOLO[4,3-C]PYRIMIDIN-5-AMINE 95.00%
  • Packaging5MG
  • Price$450.03
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2701
  • Product descriptionEED226 99%
  • Packaging5mg
  • Price$115.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBE165158
  • Product descriptionEED 226 monohydrate NEW
  • Packaging10mg
  • Price$175
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBE165158
  • Product descriptionEED 226 monohydrate NEW
  • Packaging50mg
  • Price$612.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number22031
  • Product descriptionEED226 ≥99%
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22031
  • Product descriptionEED226 ≥99%
  • Packaging5mg
  • Price$161
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22031
  • Product descriptionEED226 ≥99%
  • Packaging10mg
  • Price$283
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22031
  • Product descriptionEED226 ≥99%
  • Packaging25mg
  • Price$573
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6391
  • Product descriptionEED226 98.82%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6391
  • Product descriptionEED226 98.82%
  • Packaging10mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6391
  • Product descriptionEED226 98.82%
  • Packaging25mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6391
  • Product descriptionEED226 98.82%
  • Packaging50mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6391
  • Product descriptionEED226 98.82%
  • Packaging100mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD00005676
  • Product descriptionMAK683(EED226/Compound43) 97%
  • Packaging5mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD00005676
  • Product descriptionMAK683(EED226/Compound43) 97%
  • Packaging25mg
  • Price$347
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3723EH N-(Furan-2-Ylmethyl)-8-(4-Methylsulfonylphenyl)-[1,2,4]triazolo[4,3-C]pyrimidin-5-Amine 10mg $413 2021-12-16 Buy
American Custom Chemicals Corporation INB0005706 N-(FURAN-2-YLMETHYL)-8-(4-(METHYLSULFONYL)PHENYL)-[1,2,4]TRIAZOLO[4,3-C]PYRIMIDIN-5-AMINE 95.00% 5MG $450.03 2021-12-16 Buy
Axon Medchem Axon2701 EED226 99% 5mg $115.5 2021-12-16 Buy
Biosynth Carbosynth BE165158 EED 226 monohydrate NEW 10mg $175 2021-12-16 Buy
Biosynth Carbosynth BE165158 EED 226 monohydrate NEW 50mg $612.5 2021-12-16 Buy
Cayman Chemical 22031 EED226 ≥99% 1mg $37 2024-03-01 Buy
Cayman Chemical 22031 EED226 ≥99% 5mg $161 2024-03-01 Buy
Cayman Chemical 22031 EED226 ≥99% 10mg $283 2024-03-01 Buy
Cayman Chemical 22031 EED226 ≥99% 25mg $573 2024-03-01 Buy
ChemScene CS-6391 EED226 98.82% 5mg $60 2021-12-16 Buy
ChemScene CS-6391 EED226 98.82% 10mg $90 2021-12-16 Buy
ChemScene CS-6391 EED226 98.82% 25mg $150 2021-12-16 Buy
ChemScene CS-6391 EED226 98.82% 50mg $250 2021-12-16 Buy
ChemScene CS-6391 EED226 98.82% 100mg $450 2021-12-16 Buy
Crysdot CD00005676 MAK683(EED226/Compound43) 97% 5mg $119 2021-12-16 Buy
Crysdot CD00005676 MAK683(EED226/Compound43) 97% 25mg $347 2021-12-16 Buy

Properties

Density :1.49±0.1 g/cm3(Predicted)
storage temp. :-20°
solubility :Soluble in DMSO (up to 25 mg/ml).
pka :1.19±0.30(Predicted)
form :solid
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H320 Causes eye irritation Serious eye damage/eye irritation Category 2B Warning P264, P305+P351+P338,P337+P313
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

EED-226 (2083627-02-3) is a potent (IC50= 23.4 nM) and selective allosteric inhibitor of the EED subunit of the methyltransferase polycomb repressive complex 2 (PRC2).It caused drastic proliferation inhibition in lymphoma cells with EZH2 mutations and caused shrinkage and slower tumor growth in mice using a subcutaneous xenograft model of Karpas422.

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