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ChemicalBook >> CAS DataBase List >> Eggmanone

Eggmanone

Eggmanone price.
  • $81 - $1083
  • Product name: Eggmanone
  • CAS: 505068-32-6
  • MF: C20H20N2O2S3
  • MW: 416.58
  • EINECS:
  • MDL Number:
  • Synonyms:Eggmanone;3-(2-methylprop-2-enyl)-2-(2-oxo-2-thiophen-2-ylethyl)sulfanyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-one;5,6,7,8-Tetrahydro-3-(2-methyl-2-propen-1-yl)-2-[[2-oxo-2-(2-thienyl)ethyl]thio]-[1]benzothieno[2,3-d]pyrimidin-4(3H)-one;[1]Benzothieno[2,3-d]pyrimidin-4(3H)-one, 5,6,7,8-tetrahydro-3-(2-methyl-2-propen-1-yl)-2-[[2-oxo-2-(2-thienyl)ethyl]thio]-
25 prices
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Brand
  • aablocks
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Tocris
  • TRC
  • Usbiological
Package
  • 50
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 10
  • 100mg
  • Manufactureraablocks
  • Product numberAA01E4IP
  • Product descriptionEggmanone 98%byHPLC
  • Packaging100mg
  • Price$889
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01E4IP
  • Product descriptionEggmanone 98%byHPLC
  • Packaging50mg
  • Price$533
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01E4IP
  • Product descriptionEggmanone 98%byHPLC
  • Packaging25mg
  • Price$331
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01E4IP
  • Product descriptionEggmanone 98%byHPLC
  • Packaging10mg
  • Price$180
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01E4IP
  • Product descriptionEggmanone 98%byHPLC
  • Packaging5mg
  • Price$125
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01E4IP
  • Product descriptionEggmanone ≥95%
  • Packaging1mg
  • Price$90
  • Updated2026-05-30
  • Buy
  • ManufacturerAK Scientific
  • Product number5642CE
  • Product descriptionEggmanone
  • Packaging1mg
  • Price$187
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number5642CE
  • Product descriptionEggmanone
  • Packaging5mg
  • Price$495
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4796
  • Product descriptionEggmanone
  • Packaging5mg
  • Price$490
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4796
  • Product descriptionEggmanone
  • Packaging10mg
  • Price$257
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4796
  • Product descriptionEggmanone
  • Packaging1mg
  • Price$115
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4796
  • Product descriptionEggmanone
  • Packaging10mg
  • Price$870
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4796
  • Product descriptionEggmanone
  • Packaging50mg
  • Price$1083
  • Updated2026-05-06
  • Buy
  • ManufacturerCayman Chemical
  • Product number17751
  • Product descriptionEggmanone ≥95%
  • Packaging1mg
  • Price$81
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17751
  • Product descriptionEggmanone ≥95%
  • Packaging1mg
  • Price$90
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number17751
  • Product descriptionEggmanone ≥95%
  • Packaging5mg
  • Price$392
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA01E4IP Eggmanone 98%byHPLC 100mg $889 2026-05-30 Buy
aablocks AA01E4IP Eggmanone 98%byHPLC 50mg $533 2026-05-30 Buy
aablocks AA01E4IP Eggmanone 98%byHPLC 25mg $331 2026-05-30 Buy
aablocks AA01E4IP Eggmanone 98%byHPLC 10mg $180 2026-05-30 Buy
aablocks AA01E4IP Eggmanone 98%byHPLC 5mg $125 2026-05-30 Buy
aablocks AA01E4IP Eggmanone ≥95% 1mg $90 2026-05-30 Buy
AK Scientific 5642CE Eggmanone 1mg $187 2021-12-16 Buy
AK Scientific 5642CE Eggmanone 5mg $495 2021-12-16 Buy
ApexBio Technology C4796 Eggmanone 5mg $490 2026-05-06 Buy
ApexBio Technology C4796 Eggmanone 10mg $257 2021-12-16 Buy
ApexBio Technology C4796 Eggmanone 1mg $115 2026-05-06 Buy
ApexBio Technology C4796 Eggmanone 10mg $870 2026-05-06 Buy
ApexBio Technology C4796 Eggmanone 50mg $1083 2026-05-06 Buy
Cayman Chemical 17751 Eggmanone ≥95% 1mg $81 2024-03-01 Buy
Cayman Chemical 17751 Eggmanone ≥95% 1mg $90 2026-04-30 Buy
Cayman Chemical 17751 Eggmanone ≥95% 5mg $392 2026-04-30 Buy

Properties

storage temp. :Store at -20°C
solubility :≤0.5mg/ml in ethanol;10mg/ml in DMSO;5mg/ml in dimethyl formamide
form :crystalline solid
color :brown

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Type 4 cyclic nucleotide phosphodiesterase (PDE4) selectively inactivates the second messenger cAMP by hydrolyzing the phosphodiester bond, producing AMP. PDE4 has been reported to play a key regulatory role in Hedgehog signaling downstream of smoothened and, thus, represents a potential therapeutic target for Hedgehog-dependent cancers. Eggmanone is a selective inhibitor of PDE4 (IC50 = 72 nM) that antagonizes the Hedgehog signaling pathway. It demonstrates 40- to 50-fold lower potency at PDE3, PDE10, and PDE11 (IC50s = 3, 3.05, and 4.08 μM, respectively). Inhibition of PDE4 activity via eggmanone was shown to activate localized protein kinase A signaling, which, in turn, regulates Gli processing and translocation.