Eggmanone
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- $90 - $1083
- Product name: Eggmanone
- CAS: 505068-32-6
- MF: C20H20N2O2S3
- MW: 416.58
- EINECS:
- MDL Number:
- Synonyms:Eggmanone;3-(2-methylprop-2-enyl)-2-(2-oxo-2-thiophen-2-ylethyl)sulfanyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-one;5,6,7,8-Tetrahydro-3-(2-methyl-2-propen-1-yl)-2-[[2-oxo-2-(2-thienyl)ethyl]thio]-[1]benzothieno[2,3-d]pyrimidin-4(3H)-one;[1]Benzothieno[2,3-d]pyrimidin-4(3H)-one, 5,6,7,8-tetrahydro-3-(2-methyl-2-propen-1-yl)-2-[[2-oxo-2-(2-thienyl)ethyl]thio]-
20 prices
Selected condition：
Brand
- aablocks
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 5mg
- 50
- 10mg
- 25mg
- 50mg
- 100mg
- Manufactureraablocks
- Product numberAA01E4IP
- Product descriptionEggmanone ≥95%
- Packaging1mg
- Price$90
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E4IP
- Product descriptionEggmanone 98%byHPLC
- Packaging5mg
- Price$125
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E4IP
- Product descriptionEggmanone 98%byHPLC
- Packaging10mg
- Price$180
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E4IP
- Product descriptionEggmanone 98%byHPLC
- Packaging25mg
- Price$331
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E4IP
- Product descriptionEggmanone 98%byHPLC
- Packaging50mg
- Price$533
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E4IP
- Product descriptionEggmanone 98%byHPLC
- Packaging100mg
- Price$889
- Updated2026-05-30
- Buy
- ManufacturerAK Scientific
- Product number5642CE
- Product descriptionEggmanone
- Packaging5mg
- Price$495
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number5642CE
- Product descriptionEggmanone
- Packaging1mg
- Price$187
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4796
- Product descriptionEggmanone
- Packaging1mg
- Price$115
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC4796
- Product descriptionEggmanone
- Packaging5mg
- Price$490
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC4796
- Product descriptionEggmanone
- Packaging50mg
- Price$1083
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC4796
- Product descriptionEggmanone
- Packaging10mg
- Price$870
- Updated2026-05-06
- Buy
- ManufacturerCayman Chemical
- Product number17751
- Product descriptionEggmanone ≥95%
- Packaging10mg
- Price$696
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number17751
- Product descriptionEggmanone ≥95%
- Packaging1mg
- Price$90
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number17751
- Product descriptionEggmanone ≥95%
- Packaging5mg
- Price$392
- Updated2026-04-30
- Buy
- ManufacturerChemScene
- Product numberCS-0079344
- Product descriptionEggmanone 95.31%
- Packaging1mg
- Price$206
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01E4IP | Eggmanone ≥95% | 1mg | $90 | 2026-05-30 | Buy |
| aablocks | AA01E4IP | Eggmanone 98%byHPLC | 5mg | $125 | 2026-05-30 | Buy |
| aablocks | AA01E4IP | Eggmanone 98%byHPLC | 10mg | $180 | 2026-05-30 | Buy |
| aablocks | AA01E4IP | Eggmanone 98%byHPLC | 25mg | $331 | 2026-05-30 | Buy |
| aablocks | AA01E4IP | Eggmanone 98%byHPLC | 50mg | $533 | 2026-05-30 | Buy |
| aablocks | AA01E4IP | Eggmanone 98%byHPLC | 100mg | $889 | 2026-05-30 | Buy |
| AK Scientific | 5642CE | Eggmanone | 5mg | $495 | 2021-12-16 | Buy |
| AK Scientific | 5642CE | Eggmanone | 1mg | $187 | 2021-12-16 | Buy |
| ApexBio Technology | C4796 | Eggmanone | 1mg | $115 | 2026-05-06 | Buy |
| ApexBio Technology | C4796 | Eggmanone | 5mg | $490 | 2026-05-06 | Buy |
| ApexBio Technology | C4796 | Eggmanone | 50mg | $1083 | 2026-05-06 | Buy |
| ApexBio Technology | C4796 | Eggmanone | 10mg | $870 | 2026-05-06 | Buy |
| Cayman Chemical | 17751 | Eggmanone ≥95% | 10mg | $696 | 2026-04-30 | Buy |
| Cayman Chemical | 17751 | Eggmanone ≥95% | 1mg | $90 | 2026-04-30 | Buy |
| Cayman Chemical | 17751 | Eggmanone ≥95% | 5mg | $392 | 2026-04-30 | Buy |
| ChemScene | CS-0079344 | Eggmanone 95.31% | 1mg | $206 | 2026-06-04 | Buy |
Properties
storage temp. :Store at -20°C
solubility :≤0.5mg/ml in ethanol;10mg/ml in DMSO;5mg/ml in dimethyl formamide
form :crystalline solid
color :brown
solubility :≤0.5mg/ml in ethanol;10mg/ml in DMSO;5mg/ml in dimethyl formamide
form :crystalline solid
color :brown
Safety Information
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Description
Type 4 cyclic nucleotide phosphodiesterase (PDE4) selectively inactivates the second messenger cAMP by hydrolyzing the phosphodiester bond, producing AMP. PDE4 has been reported to play a key regulatory role in Hedgehog signaling downstream of smoothened and, thus, represents a potential therapeutic target for Hedgehog-dependent cancers. Eggmanone is a selective inhibitor of PDE4 (IC50 = 72 nM) that antagonizes the Hedgehog signaling pathway. It demonstrates 40- to 50-fold lower potency at PDE3, PDE10, and PDE11 (IC50s = 3, 3.05, and 4.08 μM, respectively). Inhibition of PDE4 activity via eggmanone was shown to activate localized protein kinase A signaling, which, in turn, regulates Gli processing and translocation.Related product price
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