Eplerenone
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- $15 - $2746
- Product name: Eplerenone
- CAS: 107724-20-9
- MF: C24H30O6
- MW: 414.49
- EINECS:600-850-8
- MDL Number:MFCD05662207
- Synonyms:(2'R,4aS,4bR,5aR,6aS,9aS,9bR,10R)-Methyl 4a,6a-diMethyl-2,4'-dioxo-3,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-2H,3'H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2'-furan]-10-carboxylate;HSDB 7522;Pregn-4-ene-7,21-dicarboxylic acid, 9,11-epoxy-17-hydroxy-3-oxo-, gamma-lactone, methyl ester, (7alpha,11alpha,17alpha)-;Eplerenone intermediate Eplerenone;(7α,11α,17α)-9,11-epoxy-17-hydroxy-3-oxo-γ-lactone-pregn-4-ene-7,21-dicarboxylic acid-7-methyl ester;Eplerenone for system suitability;Eplerenone for peak identification;EPLERENONE
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Selected condition:
Brand
- aablocks
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 10mg
- y0001706
- 5mg
- 1mg
- y0001704
- y0001705
- 25mg
- 50
- 0.1g
- 100MG
- 50mg
- 200mg
- 10
- 250mg
- 500mg
- 10mM(in1mLDMSO)
- 10mM*1mLinDMSO(Solid+Solvent)
- 1g
- 5g
- 10mM(in 1mL DMSO)
- 10g
- 25g
- 50g
- 100g
- 110 mg
- 10mM*1mLinDMSO(Solution)
- 10 mg
- Manufactureraablocks
- Product numberAA007DRJ
- Product description(2'R,4aS,4bR,5aR,6aS,9aS,9bR,10R)-Methyl 4a,6a-dimethyl-2,4'-dioxo-3,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-2H,3'H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2'-furan]-10-carboxylate ≥98%
- Packaging50mg
- Price$59
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007DRJ
- Product description(2'R,4aS,4bR,5aR,6aS,9aS,9bR,10R)-Methyl 4a,6a-dimethyl-2,4'-dioxo-3,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-2H,3'H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2'-furan]-10-carboxylate ≥98%(Assay)
- Packaging1g
- Price$65
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007DRJ
- Product description(2'R,4aS,4bR,5aR,6aS,9aS,9bR,10R)-Methyl 4a,6a-dimethyl-2,4'-dioxo-3,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-2H,3'H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2'-furan]-10-carboxylate ≥98%(Assay)
- Packaging5g
- Price$205
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007DRJ
- Product description(2'R,4aS,4bR,5aR,6aS,9aS,9bR,10R)-Methyl 4a,6a-dimethyl-2,4'-dioxo-3,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-2H,3'H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2'-furan]-10-carboxylate ≥98%
- Packaging10mg
- Price$15
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007DRJ
- Product description(2'R,4aS,4bR,5aR,6aS,9aS,9bR,10R)-Methyl 4a,6a-dimethyl-2,4'-dioxo-3,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-2H,3'H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2'-furan]-10-carboxylate ≥98%(Assay)
- Packaging25g
- Price$930
- Updated2026-05-28
- Buy
- ManufacturerAK Scientific
- Product numberJ90057
- Product descriptionEplerenone 95%
- Packaging25g
- Price$953
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberH899
- Product descriptionEplerenone 98%(HPLC)
- Packaging25g
- Price$1272
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ90057
- Product descriptionEplerenone 95%
- Packaging5g
- Price$196
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberH899
- Product descriptionEplerenone 98%(HPLC)
- Packaging5g
- Price$262
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ11424
- Product descriptionEplerenone 99%(HPLC),powder
- Packaging50mg
- Price$262
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ11424
- Product descriptionEplerenone 99%(HPLC),powder
- Packaging5mg
- Price$52
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ90057
- Product descriptionEplerenone 95%
- Packaging1g
- Price$52
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ11424
- Product descriptionEplerenone 99%(HPLC),powder
- Packaging10mg
- Price$78
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberH899
- Product descriptionEplerenone 98%(HPLC)
- Packaging1g
- Price$71
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ11424
- Product descriptionEplerenone 99%(HPLC),powder
- Packaging25mg
- Price$164
- Updated2026-06-04
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberRDL0006805
- Product descriptionEPLERENONE-13C-D3 95.00%
- Packaging5MG
- Price$496.51
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA007DRJ | (2'R,4aS,4bR,5aR,6aS,9aS,9bR,10R)-Methyl 4a,6a-dimethyl-2,4'-dioxo-3,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-2H,3'H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2'-furan]-10-carboxylate ≥98% | 50mg | $59 | 2026-05-28 | Buy |
| aablocks | AA007DRJ | (2'R,4aS,4bR,5aR,6aS,9aS,9bR,10R)-Methyl 4a,6a-dimethyl-2,4'-dioxo-3,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-2H,3'H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2'-furan]-10-carboxylate ≥98%(Assay) | 1g | $65 | 2026-05-28 | Buy |
| aablocks | AA007DRJ | (2'R,4aS,4bR,5aR,6aS,9aS,9bR,10R)-Methyl 4a,6a-dimethyl-2,4'-dioxo-3,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-2H,3'H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2'-furan]-10-carboxylate ≥98%(Assay) | 5g | $205 | 2026-05-28 | Buy |
| aablocks | AA007DRJ | (2'R,4aS,4bR,5aR,6aS,9aS,9bR,10R)-Methyl 4a,6a-dimethyl-2,4'-dioxo-3,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-2H,3'H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2'-furan]-10-carboxylate ≥98% | 10mg | $15 | 2026-05-28 | Buy |
| aablocks | AA007DRJ | (2'R,4aS,4bR,5aR,6aS,9aS,9bR,10R)-Methyl 4a,6a-dimethyl-2,4'-dioxo-3,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-2H,3'H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2'-furan]-10-carboxylate ≥98%(Assay) | 25g | $930 | 2026-05-28 | Buy |
| AK Scientific | J90057 | Eplerenone 95% | 25g | $953 | 2026-06-04 | Buy |
| AK Scientific | H899 | Eplerenone 98%(HPLC) | 25g | $1272 | 2026-06-04 | Buy |
| AK Scientific | J90057 | Eplerenone 95% | 5g | $196 | 2026-06-04 | Buy |
| AK Scientific | H899 | Eplerenone 98%(HPLC) | 5g | $262 | 2026-06-04 | Buy |
| AK Scientific | J11424 | Eplerenone 99%(HPLC),powder | 50mg | $262 | 2026-06-04 | Buy |
| AK Scientific | J11424 | Eplerenone 99%(HPLC),powder | 5mg | $52 | 2026-06-04 | Buy |
| AK Scientific | J90057 | Eplerenone 95% | 1g | $52 | 2026-06-04 | Buy |
| AK Scientific | J11424 | Eplerenone 99%(HPLC),powder | 10mg | $78 | 2026-06-04 | Buy |
| AK Scientific | H899 | Eplerenone 98%(HPLC) | 1g | $71 | 2026-06-04 | Buy |
| AK Scientific | J11424 | Eplerenone 99%(HPLC),powder | 25mg | $164 | 2026-06-04 | Buy |
| American Custom Chemicals Corporation | RDL0006805 | EPLERENONE-13C-D3 95.00% | 5MG | $496.51 | 2021-12-16 | Buy |
Properties
Melting point :241-243°C
alpha :D +5° (c = 0.437 in chloroform)
Boiling point :597.9±50.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :Store at RT
solubility :DMSO: soluble2mg/mL, clear (warmed)
form :powder
color :white to beige
λmax :240nm(lit.)
Merck :14,3625
Major Application :pharmaceutical
InChIKey :UZZAHAKTLYRDOK-MGIDJNSKSA-N
SMILES :[C@@]123[C@@]4(C)CCC(=O)C=C4C[C@@H](C(OC)=O)[C@@]1([H])[C@]1([H])CC[C@]4(CCC(=O)O4)[C@]1(C[C@@]2([H])O3)C |&1:0,1,10,15,17,21,27,29,r|
alpha :D +5° (c = 0.437 in chloroform)
Boiling point :597.9±50.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :Store at RT
solubility :DMSO: soluble2mg/mL, clear (warmed)
form :powder
color :white to beige
λmax :240nm(lit.)
Merck :14,3625
Major Application :pharmaceutical
InChIKey :UZZAHAKTLYRDOK-MGIDJNSKSA-N
SMILES :[C@@]123[C@@]4(C)CCC(=O)C=C4C[C@@H](C(OC)=O)[C@@]1([H])[C@]1([H])CC[C@]4(CCC(=O)O4)[C@]1(C[C@@]2([H])O3)C |&1:0,1,10,15,17,21,27,29,r|
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor (IC50 = 122 nM), demonstrating little activity towards other steroid receptors (IC50 > 9 μM for glucocorticoid, androgen, progesterone, and estrogen receptors). Aldosterone antagonists such as this compound have been indicated for the treatment of hypertension and heart failure.Related product price
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Suppliers and manufacturers
Suizhou Jiake Biological Engineering Co., Ltd.
Hangzhou Yiyun Guoke Biotechnology Co., Ltd.
J & K SCIENTIFIC LTD.
Meryer (Shanghai) Chemical Technology Co., Ltd.
3B Pharmachem (Wuhan) International Co.,Ltd.
Chembest Research Laboratories Limited
TCI (Shanghai) Development Co., Ltd.
Energy Chemical
JinYan Chemicals(ShangHai) Co.,Ltd.
Pure Chemistry Scientific Inc.




