Eszopiclone
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- $60 - $2000
- Product name: Eszopiclone
- CAS: 138729-47-2
- MF: C17H17ClN6O3
- MW: 388.81
- EINECS:202-303-5
- MDL Number:MFCD03700720
- Synonyms:ESOPICLONE;ESZOPICLONE;(S)-(+)-ZOPICLONE;[(9S)-8-(5-Chloropyridin-2-yl)-7-oxo-2,5,8-triazabicyclo[4.3.0]nona-1,3,5-trien-9-yl]4-methylpiperazine-1-carboxylate;Lunesta;ESZOPICLONE CIV;1-Piperazinecarboxylic acid, 4-methyl-, (5S)-6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester (9CI);1-Piperazinecarboxylic acid, 4-methyl-, 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester, (S)-
14 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- Biorbyt Ltd
- Biosynth Carbosynth
- DC Chemicals
- Medical Isotopes, Inc.
Package
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1G
- 2.5G
- 5G
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024379
- Product descriptionESZOPICLONE 95.00%
- Packaging1G
- Price$852.55
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024379
- Product descriptionESZOPICLONE 95.00%
- Packaging2.5G
- Price$1227.82
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024379
- Product descriptionESZOPICLONE 95.00%
- Packaging5G
- Price$1548.26
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146149
- Product descriptionEszopiclone >98%
- Packaging100mg
- Price$690.2
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146149
- Product descriptionEszopiclone >98%
- Packaging250mg
- Price$912.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146149
- Product descriptionEszopiclone >98%
- Packaging1g
- Price$1802
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFE156792
- Product descriptionEszopiclone
- Packaging10mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFE156792
- Product descriptionEszopiclone
- Packaging25mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFE156792
- Product descriptionEszopiclone
- Packaging50mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFE156792
- Product descriptionEszopiclone
- Packaging100mg
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFE156792
- Product descriptionEszopiclone
- Packaging250mg
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC3162
- Product descriptionEszopiclone >98%
- Packaging250mg
- Price$600
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number70052
- Product descriptionEszopiclone
- Packaging10mg
- Price$625
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number70052
- Product descriptionEszopiclone
- Packaging100mg
- Price$2000
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0024379 | ESZOPICLONE 95.00% | 1G | $852.55 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024379 | ESZOPICLONE 95.00% | 2.5G | $1227.82 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024379 | ESZOPICLONE 95.00% | 5G | $1548.26 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146149 | Eszopiclone >98% | 100mg | $690.2 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146149 | Eszopiclone >98% | 250mg | $912.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146149 | Eszopiclone >98% | 1g | $1802 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FE156792 | Eszopiclone | 10mg | $60 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FE156792 | Eszopiclone | 25mg | $125 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FE156792 | Eszopiclone | 50mg | $200 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FE156792 | Eszopiclone | 100mg | $300 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FE156792 | Eszopiclone | 250mg | $500 | 2021-12-16 | Buy |
| DC Chemicals | DC3162 | Eszopiclone >98% | 250mg | $600 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 70052 | Eszopiclone | 10mg | $625 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 70052 | Eszopiclone | 100mg | $2000 | 2021-12-16 | Buy |
Properties
Melting point :202-204°C
alpha :D20 +135 ±3° (c = 1.0 in acetone)
Boiling point :580.7±50.0 °C(Predicted)
Density :1.54±0.1 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly, Heated), Methanol (Slightly, Heated)
form :Solid
pka :6.70±0.10(Predicted)
color :White to Light Beige
InChI :InChI=1S/C17H17ClN6O3/c1-22-6-8-23(9-7-22)17(26)27-16-14-13(19-4-5-20-14)15(25)24(16)12-3-2-11(18)10-21-12/h2-5,10,16H,6-9H2,1H3/t16-/m0/s1
InChIKey :GBBSUAFBMRNDJC-INIZCTEOSA-N
SMILES :N1(C(O[C@H]2C3=NC=CN=C3C(=O)N2C2=NC=C(Cl)C=C2)=O)CCN(C)CC1
CAS DataBase Reference :138729-47-2(CAS DataBase Reference)
alpha :D20 +135 ±3° (c = 1.0 in acetone)
Boiling point :580.7±50.0 °C(Predicted)
Density :1.54±0.1 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly, Heated), Methanol (Slightly, Heated)
form :Solid
pka :6.70±0.10(Predicted)
color :White to Light Beige
InChI :InChI=1S/C17H17ClN6O3/c1-22-6-8-23(9-7-22)17(26)27-16-14-13(19-4-5-20-14)15(25)24(16)12-3-2-11(18)10-21-12/h2-5,10,16H,6-9H2,1H3/t16-/m0/s1
InChIKey :GBBSUAFBMRNDJC-INIZCTEOSA-N
SMILES :N1(C(O[C@H]2C3=NC=CN=C3C(=O)N2C2=NC=C(Cl)C=C2)=O)CCN(C)CC1
CAS DataBase Reference :138729-47-2(CAS DataBase Reference)
Safety Information
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Description
Eszopiclone is a non-benzodiazepine hypnotic agent indicated for the treatment of insomnia to induce sleep and for sleep maintenance. It has similar pharmacokinetic and pharmacodynamic parameters as the previously marketed non-benzodiazepine hypnotics zolpidem and zaleplon. However, unlike its predecessors, eszopiclone is not restricted to short-term treatment of insomnia. Clinical studies of up to 6 months of use show that patients do not develop tolerance to its effect. Eszopiclone is the (S)-enantiomer of zopiclone, which has been marketed as the racemic mixture in Europe for almost 20 years. These agents belong to the cyclopyrrolone class of drugs that act as agonists at the type A GABA receptor. Eszopiclone has approximately 50-fold higher binding affinity than its antipode (R)-zopiclone for GABA-A receptor (IC50=21 and 1130 nM, respectively). In addition, the two enantiomers exhibit significant differences in their pharmacokinetic parameters and in vivo efficacy. In healthy volunteers, eszopiclone has 2-fold higher Cmax and 2-fold greater elimination half-life than the (R)-enantiomer.The two most frequent adverse events associated with eszopiclone treatment are unpleasant taste and headache. Other less frequent side effects include somnolence, dry mouth, and nausea.More related product prices
6-(5-Chloro-2-pyridyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo[3,4-b]pyrazin-5-one SEP 174559 Hydrochloride Ozagrel Pramipexole dihydrochloride (S)-(+)-2-Chlorophenylglycine methyl ester ZOPICLONE N-OXIDE 6-(5-Chloro-2-pyridyl)-5H-pyrrolo[3,4-b]pyrazine-5,7(6H)-dione Pyrrole Zopiclone EszopicloneRelated product price
Suppliers and manufacturers
Beijing Cooperate Pharmaceutical Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
Shanghai Time Chemicals CO., Ltd.
Hangzhou FandaChem Co.,Ltd.
Casorganics US Corp
Chongqing Chemdad Co., Ltd
CONIER CHEM AND PHARMA LIMITED
