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ChemicalBook >> CAS DataBase List >> FRAX1036

FRAX1036

FRAX1036 price.
  • $13 - $2418
  • Product name: FRAX1036
  • CAS: 1432908-05-8
  • MF: C28H32ClN7O
  • MW: 518.05
  • EINECS:
  • MDL Number:MFCD30187513
  • Synonyms:FRAX1036;FRAX1036 (Free base);FRAX-1036;FRAX 1036;CS-2271;Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-[2-chloro-4-(6-methyl-2-pyrazinyl)phenyl]-8-ethyl-2-[[2-(1-methyl-4-piperidinyl)ethyl]amino]-;6-(2-Chloro-4-(6-methylpyrazin-2-yl)phenyl)-8-ethyl-2-((2-(1-methylpiperidin-4-yl)ethyl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one;FRAX 1036,Inhibitor,p21 activated kinases,PAK,FRAX1036,inhibit,FRAX-1036;6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-{[2-(1-methylpiperidin-4-yl)ethyl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one
Price49 Properties Safety Information Description
49 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
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  • 1g
  • 5 mg
  • 25 mg
  • Manufactureraablocks
  • Product numberAA009CJR
  • Product descriptionFRAX1036 98+%
  • Packaging1mg
  • Price$13
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009CJR
  • Product descriptionFRAX1036 98+%
  • Packaging5mg
  • Price$25
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009CJR
  • Product descriptionFRAX1036 98+%
  • Packaging10mg
  • Price$34
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009CJR
  • Product descriptionFRAX1036 98+%
  • Packaging25mg
  • Price$55
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009CJR
  • Product descriptionFRAX1036 98+%
  • Packaging50mg
  • Price$94
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009CJR
  • Product descriptionFRAX1036 98+%
  • Packaging100mg
  • Price$145
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY229086
  • Product descriptionFRAX1036 97.00%
  • Packaging50MG
  • Price$110
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number9316DU
  • Product description6-[2-Chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-[2-(1-methylpiperidin-4-yl)ethylamino]pyrido[2,3-d]pyrimidin-7-one
  • Packaging25mg
  • Price$974
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA374154
  • Product descriptionFRAX1036 98+%
  • Packaging1g
  • Price$1433
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA374154
  • Product descriptionFRAX1036 98+%
  • Packaging250mg
  • Price$574
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA374154
  • Product descriptionFRAX1036 98+%
  • Packaging10mg
  • Price$126
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA374154
  • Product descriptionFRAX1036 98+%
  • Packaging1mg
  • Price$46
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA374154
  • Product descriptionFRAX1036 98+%
  • Packaging25mg
  • Price$170
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA374154
  • Product descriptionFRAX1036 98+%
  • Packaging50mg
  • Price$221
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA374154
  • Product descriptionFRAX1036 98+%
  • Packaging5mg
  • Price$92
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA374154
  • Product descriptionFRAX1036 98+%
  • Packaging100mg
  • Price$287
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA009CJR FRAX1036 98+% 1mg $13 2026-05-28 Buy
aablocks AA009CJR FRAX1036 98+% 5mg $25 2026-05-28 Buy
aablocks AA009CJR FRAX1036 98+% 10mg $34 2026-05-28 Buy
aablocks AA009CJR FRAX1036 98+% 25mg $55 2026-05-28 Buy
aablocks AA009CJR FRAX1036 98+% 50mg $94 2026-05-28 Buy
aablocks AA009CJR FRAX1036 98+% 100mg $145 2026-05-28 Buy
ACHEMBLOCK Y229086 FRAX1036 97.00% 50MG $110 2026-05-27 Buy
AK Scientific 9316DU 6-[2-Chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-[2-(1-methylpiperidin-4-yl)ethylamino]pyrido[2,3-d]pyrimidin-7-one 25mg $974 2021-12-16 Buy
Ambeed A374154 FRAX1036 98+% 1g $1433 2021-12-16 Buy
Ambeed A374154 FRAX1036 98+% 250mg $574 2021-12-16 Buy
Ambeed A374154 FRAX1036 98+% 10mg $126 2021-12-16 Buy
Ambeed A374154 FRAX1036 98+% 1mg $46 2021-12-16 Buy
Ambeed A374154 FRAX1036 98+% 25mg $170 2021-12-16 Buy
Ambeed A374154 FRAX1036 98+% 50mg $221 2021-12-16 Buy
Ambeed A374154 FRAX1036 98+% 5mg $92 2021-12-16 Buy
Ambeed A374154 FRAX1036 98+% 100mg $287 2021-12-16 Buy
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Properties

Boiling point :669.8±65.0 °C(Predicted)
Density :1+-.0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :crystalline solid
pka :9.46±0.10(Predicted)
color :White to light yellow
InChIKey :RYCBSFIKWACFBY-UHFFFAOYSA-N
SMILES :Clc1c(ccc(c1)c5nc(cnc5)C)c2[c]([n](c3nc(ncc3c2)NCCC4CCN(CC4)C)CC)=O

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

FRAX1036 is a selective inhibitor of p21-activated kinase 1 (PAK1), a serine/threonine kinase downstream of Rac1 and Cdc42 that is involved in tumorigenesis. It can induce apoptosis in breast cancer cells and has been shown to potentiate the activity of the microtubule stabilizing agent, docetaxel . Disruption of PAK1 via FRAX1036 has been used to inhibit oncogenic KRAS signaling in non-small cell lung cancer cells.

More related product prices

FRAX1036 G-5555 1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol 6-(2-Chloro-4-thiazol-5-yl-phenyl)-8-ethyl-2-[4-(4-Methyl-piperazin-1-yl)-phenylaMino]-8H-pyrido[2,3-d]pyriMidin-7-one PF-3758309

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Suppliers and manufacturers

BOC Sciences Haoyuan Chemexpress Co., Ltd. MedChemexpress LLC Shanghai Lollane Biological Technology Co.,Ltd. Shanghai EFE Biological Technology Co., Ltd. Shanghai YuanYe Biotechnology Co., Ltd. ShangHai Biochempartner Co.,Ltd Shanghai Yunpun industrial Co.,Ltd Shanghai Chaolan Chemical Technology Center Beijing Solarbio Science & Tecnology Co., Ltd.