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ChemicalBook >> CAS DataBase List >> GLPG-1690

GLPG-1690

$15 - $2400
Product name: GLPG-1690
CAS: 1628260-79-6
MF: C30H33FN8O2S
MW: 588.7
EINECS:-0
MDL Number:MFCD31544330
Synonyms:GLPG-1690;5-Thiazolecarbonitrile, 2-[[2-ethyl-6-[4-[2-(3-hydroxy-1-azetidinyl)-2-oxoethyl]-1-piperazinyl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)-;CS-2644;GLPG 1690;GLPG1690;GLPG-1690; GLPG 1690; GLPG1690; ZIRITAXESTAT.;GLPG-1690 USP/EP/BP;2-((2-ethyl-6-(4-(2-(3-hydroxyazetidin-1-yl)-2-oxoethyl)piperazin-1-yl)-8-methylimidazo[1,2-a]pyridin-3-yl)(methyl)amino)-4-(4-fluorophenyl)thiazole-5-carbonitrile;ziritaxestat

Price34 Properties Safety Information Description

34 prices

Selected condition：

Brand

aablocks
ACHEMBLOCK
AK Scientific
American Custom Chemicals Corporation
Axon Medchem
Cayman Chemical
ChemScene
DC Chemicals
TRC

Package

10mM*1mLinDMSO
1mg
5mg
10mg
25MG
50mg
100mg
250mg
1g

Manufactureraablocks
Product numberAA001TDD
Product description5-Thiazolecarbonitrile, 2-[[2-ethyl-6-[4-[2-(3-hydroxy-1-azetidinyl)-2-oxoethyl]-1-piperazinyl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)- 99%
Packaging1mg
Price$15
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA001TDD
Product description5-Thiazolecarbonitrile, 2-[[2-ethyl-6-[4-[2-(3-hydroxy-1-azetidinyl)-2-oxoethyl]-1-piperazinyl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)- 99%
Packaging5mg
Price$31
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA001TDD
Product description5-Thiazolecarbonitrile, 2-[[2-ethyl-6-[4-[2-(3-hydroxy-1-azetidinyl)-2-oxoethyl]-1-piperazinyl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)- 99%
Packaging10mg
Price$42
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA001TDD
Product description5-Thiazolecarbonitrile, 2-[[2-ethyl-6-[4-[2-(3-hydroxy-1-azetidinyl)-2-oxoethyl]-1-piperazinyl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)- 95
Packaging50mg
Price$179
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA001TDD
Product description5-Thiazolecarbonitrile, 2-[[2-ethyl-6-[4-[2-(3-hydroxy-1-azetidinyl)-2-oxoethyl]-1-piperazinyl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)- 95%
Packaging100mg
Price$248
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA001TDD
Product description5-Thiazolecarbonitrile, 2-[[2-ethyl-6-[4-[2-(3-hydroxy-1-azetidinyl)-2-oxoethyl]-1-piperazinyl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)- 95%
Packaging250mg
Price$400
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product numberQ65611
Product description2-((2-ethyl-6-(4-(2-(3-hydroxyazetidin-1-yl)-2-oxoethyl)piperazin-1-yl)-8-methylimidazo[1,2-a]pyridin-3-yl)(methyl)amino)-4-(4-fluorophenyl)thiazole-5-carbonitrile 98%
Packaging100MG
Price$235
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberQ65611
Product description2-((2-ethyl-6-(4-(2-(3-hydroxyazetidin-1-yl)-2-oxoethyl)piperazin-1-yl)-8-methylimidazo[1,2-a]pyridin-3-yl)(methyl)amino)-4-(4-fluorophenyl)thiazole-5-carbonitrile 98%
Packaging25MG
Price$110
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product number3709EB
Product descriptionZiritaxestat
Packaging25mg
Price$479
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number3709EB
Product descriptionZiritaxestat
Packaging50mg
Price$758
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberINB0004921
Product descriptionGLPG1690 95.00%
Packaging5MG
Price$452.62
Updated2021-12-16
Buy

ManufacturerAxon Medchem
Product numberAxon3094
Product descriptionGLPG1690-Ziritaxestat 98%
Packaging50mg
Price$363
Updated2021-12-16
Buy

ManufacturerAxon Medchem
Product numberAxon3094
Product descriptionGLPG1690
Packaging50mg
Price$363
Updated2026-05-19
Buy

ManufacturerAxon Medchem
Product numberAxon3094
Product descriptionGLPG1690
Packaging10mg
Price$121
Updated2026-05-19
Buy

ManufacturerCayman Chemical
Product number25498
Product descriptionGLPG1690 ≥98%
Packaging10mg
Price$166
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number25498
Product descriptionGLPG1690 ≥98%
Packaging5mg
Price$93
Updated2024-03-01
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA001TDD	5-Thiazolecarbonitrile, 2-[[2-ethyl-6-[4-[2-(3-hydroxy-1-azetidinyl)-2-oxoethyl]-1-piperazinyl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)- 99%	1mg	$15	2026-05-28	Buy
aablocks	AA001TDD	5-Thiazolecarbonitrile, 2-[[2-ethyl-6-[4-[2-(3-hydroxy-1-azetidinyl)-2-oxoethyl]-1-piperazinyl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)- 99%	5mg	$31	2026-05-28	Buy
aablocks	AA001TDD	5-Thiazolecarbonitrile, 2-[[2-ethyl-6-[4-[2-(3-hydroxy-1-azetidinyl)-2-oxoethyl]-1-piperazinyl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)- 99%	10mg	$42	2026-05-28	Buy
aablocks	AA001TDD	5-Thiazolecarbonitrile, 2-[[2-ethyl-6-[4-[2-(3-hydroxy-1-azetidinyl)-2-oxoethyl]-1-piperazinyl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)- 95	50mg	$179	2026-05-28	Buy
aablocks	AA001TDD	5-Thiazolecarbonitrile, 2-[[2-ethyl-6-[4-[2-(3-hydroxy-1-azetidinyl)-2-oxoethyl]-1-piperazinyl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)- 95%	100mg	$248	2026-05-28	Buy
aablocks	AA001TDD	5-Thiazolecarbonitrile, 2-[[2-ethyl-6-[4-[2-(3-hydroxy-1-azetidinyl)-2-oxoethyl]-1-piperazinyl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)- 95%	250mg	$400	2026-05-28	Buy
ACHEMBLOCK	Q65611	2-((2-ethyl-6-(4-(2-(3-hydroxyazetidin-1-yl)-2-oxoethyl)piperazin-1-yl)-8-methylimidazo[1,2-a]pyridin-3-yl)(methyl)amino)-4-(4-fluorophenyl)thiazole-5-carbonitrile 98%	100MG	$235	2026-05-27	Buy
ACHEMBLOCK	Q65611	2-((2-ethyl-6-(4-(2-(3-hydroxyazetidin-1-yl)-2-oxoethyl)piperazin-1-yl)-8-methylimidazo[1,2-a]pyridin-3-yl)(methyl)amino)-4-(4-fluorophenyl)thiazole-5-carbonitrile 98%	25MG	$110	2026-05-27	Buy
AK Scientific	3709EB	Ziritaxestat	25mg	$479	2021-12-16	Buy
AK Scientific	3709EB	Ziritaxestat	50mg	$758	2021-12-16	Buy
American Custom Chemicals Corporation	INB0004921	GLPG1690 95.00%	5MG	$452.62	2021-12-16	Buy
Axon Medchem	Axon3094	GLPG1690-Ziritaxestat 98%	50mg	$363	2021-12-16	Buy
Axon Medchem	Axon3094	GLPG1690	50mg	$363	2026-05-19	Buy
Axon Medchem	Axon3094	GLPG1690	10mg	$121	2026-05-19	Buy
Cayman Chemical	25498	GLPG1690 ≥98%	10mg	$166	2024-03-01	Buy
Cayman Chemical	25498	GLPG1690 ≥98%	5mg	$93	2024-03-01	Buy

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Properties

Density :1.42±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:70.84(Max Conc. mg/mL);120.32(Max Conc. mM)
Ethanol:4.0(Max Conc. mg/mL);6.79(Max Conc. mM) form :A crystalline solid
pka :13.72±0.20(Predicted)
color :White to off-white
InChIKey :REQQVBGILUTQNN-UHFFFAOYSA-N
SMILES :S1C(C#N)=C(C2=CC=C(F)C=C2)N=C1N(C1N2C(=NC=1CC)C(C)=CC(N1CCN(CC(N3CC(O)C3)=O)CC1)=C2)C

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

GLPG1690 is a selective autotaxin inhibitor discovered by Galapagos, with potential application in idiopathic pulmonary disease (IPF). In a Phase 1 study in healthy human volunteers, GLPG1690 demonstrated favorable safety and tolerability, as well as a strong pharmacodynamic signal implying target engagement.

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Suppliers and manufacturers

TargetMol Chemicals Inc.

$72.00 /10mg
Ziritaxestat CAS:1628260-79-6

Dideu Industries Group Limited

$1.10 /1g
GLPG-1690 USP/EP/BP CAS:1628260-79-6

ATK CHEMICAL COMPANY LIMITED

BOC Sciences

CONIER CHEM AND PHARMA LIMITED

HANGZHOU CLAP TECHNOLOGY CO.,LTD

Zhejiang J&C Biological Technology Co.,Limited

InvivoChem

HANGZHOU LEAP CHEM CO., LTD.