GO 6976
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- $42 - $3900
- Product name: GO 6976
- CAS: 136194-77-9
- MF: C24H18N4O
- MW: 378.43
- EINECS:200-258-5
- MDL Number:MFCD00236434
- Synonyms:InSolution? G? 6976 ;5,6,7,13-Tetrahydro-13-methyl-5-oxo-12H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-propanenitrile;Go6976,5,6,7,13-Tetrahydro-13-Methyl-5-oxo-12H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-propanenitrile;PD406976;12-(2-CYANOETHYL)-6,7,12,13-TETRAHYDRO-13-METHYL-5-OXO-5H-INDOLO(2,3-A)PYRROLO(3,4-C)-CARBAZOLE;12-2(2-CYANOETHYL)-6,7,12,13-TETRAHYDRO-13-METHYL-5-OXO-5H-INDOLO[2,3-A]PYRROLO[3,4-C]CARBAZOLE;GO 6976;G6976
47 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Apolloscientific
- Arctom
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 500μg
- 1mg
- 2mg
- 2.5mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100MG
- 250mg
- 500U
- 1g
- 1ml
- Manufactureraablocks
- Product numberAA009A7L
- Product descriptionGo6976 98%
- Packaging1mg
- Price$42
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009A7L
- Product descriptionGo6976 ≥98%
- Packaging5mg
- Price$122
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009A7L
- Product descriptionGo6976 ≥98%
- Packaging25mg
- Price$458
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009A7L
- Product descriptionGo6976 ≥98%
- Packaging50mg
- Price$823
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228829
- Product descriptionGo6976 96%
- Packaging100MG
- Price$1070
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228829
- Product descriptionGo6976 96%
- Packaging25MG
- Price$475
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228829
- Product descriptionGo6976 96%
- Packaging5MG
- Price$195
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberSYN5462
- Product descriptionGo6976
- Packaging50mg
- Price$1880
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8341
- Product descriptionGo 6976
- Packaging5mg
- Price$160
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8341
- Product descriptionGo 6976
- Packaging25mg
- Price$450
- Updated2026-05-06
- Buy
- ManufacturerApolloscientific
- Product numberBIG697
- Product descriptionGo 6976 98%
- Packaging25mg
- Price$554
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIG697
- Product descriptionGo 6976 98%
- Packaging10mg
- Price$279
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIG697
- Product descriptionGo 6976 98%
- Packaging5mg
- Price$165
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIG697
- Product descriptionGo 6976 98%
- Packaging1mg
- Price$66
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIG697
- Product descriptionGo 6976 98%
- Packaging50mg
- Price$997
- Updated2026-06-04
- Buy
- ManufacturerArctom
- Product numberCFN60288
- Product descriptionGo6976
- Packaging5mg
- Price$338
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA009A7L | Go6976 98% | 1mg | $42 | 2026-05-28 | Buy |
| aablocks | AA009A7L | Go6976 ≥98% | 5mg | $122 | 2026-05-28 | Buy |
| aablocks | AA009A7L | Go6976 ≥98% | 25mg | $458 | 2026-05-28 | Buy |
| aablocks | AA009A7L | Go6976 ≥98% | 50mg | $823 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y228829 | Go6976 96% | 100MG | $1070 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y228829 | Go6976 96% | 25MG | $475 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y228829 | Go6976 96% | 5MG | $195 | 2026-05-27 | Buy |
| AK Scientific | SYN5462 | Go6976 | 50mg | $1880 | 2021-12-16 | Buy |
| ApexBio Technology | A8341 | Go 6976 | 5mg | $160 | 2026-05-06 | Buy |
| ApexBio Technology | A8341 | Go 6976 | 25mg | $450 | 2026-05-06 | Buy |
| Apolloscientific | BIG697 | Go 6976 98% | 25mg | $554 | 2026-06-04 | Buy |
| Apolloscientific | BIG697 | Go 6976 98% | 10mg | $279 | 2026-06-04 | Buy |
| Apolloscientific | BIG697 | Go 6976 98% | 5mg | $165 | 2026-06-04 | Buy |
| Apolloscientific | BIG697 | Go 6976 98% | 1mg | $66 | 2026-06-04 | Buy |
| Apolloscientific | BIG697 | Go 6976 98% | 50mg | $997 | 2026-06-04 | Buy |
| Arctom | CFN60288 | Go6976 | 5mg | $338 | 2021-12-16 | Buy |
Properties
Melting point :>221°C (dec.)
Boiling point :652.3±55.0 °C(Predicted)
Density :1.41±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :Acetonitrile (Very Slightly, Heated), DMSO (Slightly), Methanol (Very Slightly)
form :Off-white solid
pka :14.39±0.20(Predicted)
color :White to Off-White
InChI :InChI=1S/C24H18N4O/c1-27-17-9-4-2-7-14(17)20-21-16(13-26-24(21)29)19-15-8-3-5-10-18(15)28(12-6-11-25)23(19)22(20)27/h2-5,7-10H,6,12-13H2,1H3,(H,26,29)
InChIKey :VWVYILCFSYNJHF-UHFFFAOYSA-N
SMILES :N1(C)C2=C(C=CC=C2)C2=C1C1N(CCC#N)C3=C(C=1C1CNC(=O)C=12)C=CC=C3
Boiling point :652.3±55.0 °C(Predicted)
Density :1.41±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :Acetonitrile (Very Slightly, Heated), DMSO (Slightly), Methanol (Very Slightly)
form :Off-white solid
pka :14.39±0.20(Predicted)
color :White to Off-White
InChI :InChI=1S/C24H18N4O/c1-27-17-9-4-2-7-14(17)20-21-16(13-26-24(21)29)19-15-8-3-5-10-18(15)28(12-6-11-25)23(19)22(20)27/h2-5,7-10H,6,12-13H2,1H3,(H,26,29)
InChIKey :VWVYILCFSYNJHF-UHFFFAOYSA-N
SMILES :N1(C)C2=C(C=CC=C2)C2=C1C1N(CCC#N)C3=C(C=1C1CNC(=O)C=12)C=CC=C3
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
G? 6976 is a nonglycosidic indolocarbazole that inhibits protein kinase C (PKC) with IC50 values of 2.3 and 6.2 nM for PKCα and PKCβ1, respectively. It does not inhibit the activity of PKCδ, PKCε, or PKCζ (IC50s > 3 μM), indicating a preference for the Ca2+-dependent subtypes, PKCα and PKCβ1. G? 6976 also inhibits the checkpoint kinases Chk1/2. It was shown to abrogate DNA damage-induced S- and G2-phase cell cycle arrest, leading to cytotoxicity in p53 mutant tumor cells.Related product price
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Suppliers and manufacturers
Shanghai Boyle Chemical Co., Ltd.
J & K SCIENTIFIC LTD.
3B Pharmachem (Wuhan) International Co.,Ltd.
Chemsky (shanghai) International Co.,Ltd
BOC Sciences
AdooQ BioScience, LLC
TargetMol Chemicals Inc.
Jinan Mingya Medical Technology Co., Ltd.
ShangHai Caerulum Pharma Discovery Co., Ltd.
Bide Pharmatech Ltd.