GSK2982772
|
- $24 - $2400
- Product name: GSK2982772
- CAS: 1622848-92-3
- MF: C20H19N5O3
- MW: 377.4
- EINECS:
- MDL Number:MFCD30489467
- Synonyms:(S)-5-benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)-4H-1,2,4-triazole-3-carboxamide;5184;GSK2982772;RIP1 inhibitor GS2982772;CS-2502;(S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-4H-1,2,4-TRIAZOLE-3-CAR;GSK 2982772;GSK-2982772;1H-1,2,4-Triazole-5-carboxamide, 3-(phenylmethyl)-N-[(3S)-2,3,4,5-tetrahydro-5-methyl-4-oxo-1,5-benzoxazepin-3-yl]-
64 prices
Selected condition:
Brand
- A2B
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Arctom
- Ark Pharm
- AvaChem
- Axon Medchem
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
Package
- 10mM*1mLinDMSO(Solution)
- 1mg
- 2mg
- 5mg
- 2x5mg
- 10mg
- 25mg
- 50mg
- 250mg
- 10mM*1mLinDMSO
- 100mg
- 1G
- 10mM(1mLinDMSO)
- 10mM*1mLinDMSO(Solid+Solvent)
- ManufacturerA2B
- Product numberAF01297
- Product description(S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99%
- Packaging100mg
- Price$331
- Updated2026-05-25
- Buy
- ManufacturerA2B
- Product numberAF01297
- Product description(S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99%
- Packaging50mg
- Price$210
- Updated2026-05-25
- Buy
- ManufacturerA2B
- Product numberAF01297
- Product description(S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99%
- Packaging25mg
- Price$137
- Updated2026-05-25
- Buy
- ManufacturerA2B
- Product numberAF01297
- Product description(S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99%
- Packaging10mg
- Price$82
- Updated2026-05-25
- Buy
- ManufacturerA2B
- Product numberAF01297
- Product description(S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99%
- Packaging5mg
- Price$55
- Updated2026-05-25
- Buy
- ManufacturerA2B
- Product numberAF01297
- Product description(S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99%
- Packaging1mg
- Price$24
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA00AQVP
- Product description(S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99%
- Packaging1mg
- Price$27
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00AQVP
- Product description(S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99%
- Packaging5mg
- Price$61
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00AQVP
- Product description(S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99%
- Packaging10mg
- Price$91
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00AQVP
- Product description(S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99%
- Packaging25mg
- Price$155
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00AQVP
- Product description(S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99%
- Packaging50mg
- Price$237
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00AQVP
- Product description(S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99%
- Packaging100mg
- Price$376
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65628
- Product description(S)-5-benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)-1H-1,2,4-triazole-3-carboxamide 97%
- Packaging100MG
- Price$225
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65628
- Product description(S)-5-benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)-1H-1,2,4-triazole-3-carboxamide 97%
- Packaging1G
- Price$1125
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number0546DY
- Product descriptionCID77108121
- Packaging50mg
- Price$657
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA363017
- Product description(S)-3-Benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)-1H-1,2,4-triazole-5-carboxamide 99+%
- Packaging250mg
- Price$636
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| A2B | AF01297 | (S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99% | 100mg | $331 | 2026-05-25 | Buy |
| A2B | AF01297 | (S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99% | 50mg | $210 | 2026-05-25 | Buy |
| A2B | AF01297 | (S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99% | 25mg | $137 | 2026-05-25 | Buy |
| A2B | AF01297 | (S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99% | 10mg | $82 | 2026-05-25 | Buy |
| A2B | AF01297 | (S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99% | 5mg | $55 | 2026-05-25 | Buy |
| A2B | AF01297 | (S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99% | 1mg | $24 | 2026-05-25 | Buy |
| aablocks | AA00AQVP | (S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99% | 1mg | $27 | 2026-05-28 | Buy |
| aablocks | AA00AQVP | (S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99% | 5mg | $61 | 2026-05-28 | Buy |
| aablocks | AA00AQVP | (S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99% | 10mg | $91 | 2026-05-28 | Buy |
| aablocks | AA00AQVP | (S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99% | 25mg | $155 | 2026-05-28 | Buy |
| aablocks | AA00AQVP | (S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99% | 50mg | $237 | 2026-05-28 | Buy |
| aablocks | AA00AQVP | (S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE 99% | 100mg | $376 | 2026-05-28 | Buy |
| ACHEMBLOCK | Q65628 | (S)-5-benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)-1H-1,2,4-triazole-3-carboxamide 97% | 100MG | $225 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65628 | (S)-5-benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)-1H-1,2,4-triazole-3-carboxamide 97% | 1G | $1125 | 2026-05-27 | Buy |
| AK Scientific | 0546DY | CID77108121 | 50mg | $657 | 2021-12-16 | Buy |
| Ambeed | A363017 | (S)-3-Benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)-1H-1,2,4-triazole-5-carboxamide 99+% | 250mg | $636 | 2021-12-16 | Buy |
Properties
Density :1.40±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
form :solid
pka :8.80±0.40(Predicted)
color :Off-white
Stability :Stable for 2 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :LYPAFUINURXJSG-AWEZNQCLSA-N
SMILES :N1C(C(N[C@@H]2C(=O)N(C)C3=CC=CC=C3OC2)=O)=NC(CC2=CC=CC=C2)=N1
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
form :solid
pka :8.80±0.40(Predicted)
color :Off-white
Stability :Stable for 2 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :LYPAFUINURXJSG-AWEZNQCLSA-N
SMILES :N1C(C(N[C@@H]2C(=O)N(C)C3=CC=CC=C3OC2)=O)=NC(CC2=CC=CC=C2)=N1
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
(S)-5-benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)-4H-1,2,4-triazole-3-carboxamide, also known as GSK2982772, is a first-in-class receptor interacting protein 1(RIP1)-kinase specific clinical candidate for the treatment of inflammatory disease. It is an inhibitor of RIP1 that regulates necroptosis and inflammation and may play an important role in contributing to a variety of human pathologies, including immune-mediated inflammatory diseases. It has excellent activity in blocking many TNF-dependent cellular responses. Highlighting its potential as a novel anti-inflammatory agent, the inhibitor was also able to reduce spontaneous production of cytokines from human ulcerative colitis explants.More related product prices
6-[(1-acetylpiperidin-4-yl)amino]-N-[(2S)-2-hydroxy-3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]pyrimidine-4-carboxamide GSK-2881078 GSK2636771 MethanesulfonaMide, N-[5-[4-[5-[[(2R,6S)-2,6-diMethyl-4-Morpholinyl]Methyl]-2-oxazolyl]-1H-indazol-6-yl]-2-Methoxy-3-pyridinyl]-, rel- N-(4-ethylphenyl)-3-(hydroxymethyl)-N-isobutyl-4-((tetrahydro-2H-pyran-4-yl)methoxy)benzenesulfonamide cyclopentyl 2-cyclohexyl-2-((6-(3-(hydroxyamino)-3-oxopropyl)pyridin-3-yl)methylamino)acetate 864082-47-3 GSK-2256098 GSK 2334470 GSK J4 HCl 1346574-57-9 GSK2837808A 942206-85-1 GSK484 GSK864 GSK6853 GSK 2033Related product price
Suppliers and manufacturers
Dezhou LonWel Pharmaceutical Technology Co., Ltd.
Changzhou Chenhong Biotechnology Co., Ltd.
Shanghai Boyle Chemical Co., Ltd.
ShangHai Caerulum Pharma Discovery Co., Ltd.
Hangzhou J&H Chemical Co., Ltd.
Shanghai YuanQi Biotechnology Co., Ltd.
Shanghai Lollane Biological Technology Co.,Ltd.
Shanghaizehan biopharma technology co., Ltd.
ShangHai Angti Biotechnology Co., Ltd.
Chengdu DingDang Pharmaceutical Co., Ltd.




