GSK591
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- $32 - $1800
- Product name: GSK591
- CAS: 1616391-87-7
- MF: C22H28N4O2
- MW: 380.48
- EINECS:-0
- MDL Number:MFCD30187524
- Synonyms:GSK591 (EPZ-015866);EPZ015866;GSK591(EPZ015866,GSK3203591);EPZ015866(GSK591);EPZ015866,GSK3203591;GSK591;GSK3203591(EPZ015866);EPZ-015866;EPZ 015866;GSK-591;GSK 591;GSK3203591;GSK-3203591;GSK 3203591
30 prices
Selected condition：
Brand
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
Package
- 5MG
- 10mM*1mLinDMSO
- 1mg
- 10mg
- 25MG
- 50mg
- 100MG
- 250mg
- 1G
- ManufacturerACHEMBLOCK
- Product numberS72374
- Product description(S)-2-(cyclobutylamino)-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)isonicotinamide 98%
- Packaging5MG
- Price$45
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberS72374
- Product description(S)-2-(cyclobutylamino)-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)isonicotinamide 98%
- Packaging25MG
- Price$95
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberS72374
- Product description(S)-2-(cyclobutylamino)-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)isonicotinamide 98%
- Packaging100MG
- Price$295
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberS72374
- Product description(S)-2-(cyclobutylamino)-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)isonicotinamide 98%
- Packaging1G
- Price$1310
- Updated2026-05-25
- Buy
- ManufacturerAK Scientific
- Product number0912EF
- Product description2-(Cyclobutylamino)-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide
- Packaging25mg
- Price$522
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6182
- Product descriptionGSK591
- Packaging25mg
- Price$334
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6182
- Product descriptionGSK591
- Packaging25mg
- Price$334
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB6182
- Product descriptionGSK591
- Packaging5mg
- Price$103
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6182
- Product descriptionGSK591
- Packaging5mg
- Price$103
- Updated2026-05-06
- Buy
- ManufacturerCayman Chemical
- Product number18354
- Product descriptionGSK591 ≥95%
- Packaging5mg
- Price$103
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number18354
- Product descriptionGSK591 ≥95%
- Packaging5mg
- Price$93
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18354
- Product descriptionGSK591 ≥95%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18354
- Product descriptionGSK591 ≥95%
- Packaging1mg
- Price$36
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number18354
- Product descriptionGSK591 ≥95%
- Packaging25mg
- Price$381
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18354
- Product descriptionGSK591 ≥95%
- Packaging25mg
- Price$420
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number18354
- Product descriptionGSK591 ≥95%
- Packaging10mg
- Price$169
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | S72374 | (S)-2-(cyclobutylamino)-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)isonicotinamide 98% | 5MG | $45 | 2026-05-25 | Buy |
| ACHEMBLOCK | S72374 | (S)-2-(cyclobutylamino)-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)isonicotinamide 98% | 25MG | $95 | 2026-05-25 | Buy |
| ACHEMBLOCK | S72374 | (S)-2-(cyclobutylamino)-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)isonicotinamide 98% | 100MG | $295 | 2026-05-25 | Buy |
| ACHEMBLOCK | S72374 | (S)-2-(cyclobutylamino)-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)isonicotinamide 98% | 1G | $1310 | 2026-05-25 | Buy |
| AK Scientific | 0912EF | 2-(Cyclobutylamino)-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide | 25mg | $522 | 2021-12-16 | Buy |
| ApexBio Technology | B6182 | GSK591 | 25mg | $334 | 2021-12-16 | Buy |
| ApexBio Technology | B6182 | GSK591 | 25mg | $334 | 2026-05-06 | Buy |
| ApexBio Technology | B6182 | GSK591 | 5mg | $103 | 2021-12-16 | Buy |
| ApexBio Technology | B6182 | GSK591 | 5mg | $103 | 2026-05-06 | Buy |
| Cayman Chemical | 18354 | GSK591 ≥95% | 5mg | $103 | 2026-04-30 | Buy |
| Cayman Chemical | 18354 | GSK591 ≥95% | 5mg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 18354 | GSK591 ≥95% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 18354 | GSK591 ≥95% | 1mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 18354 | GSK591 ≥95% | 25mg | $381 | 2024-03-01 | Buy |
| Cayman Chemical | 18354 | GSK591 ≥95% | 25mg | $420 | 2026-04-30 | Buy |
| Cayman Chemical | 18354 | GSK591 ≥95% | 10mg | $169 | 2024-03-01 | Buy |
Properties
Boiling point :648.4±55.0 °C(Predicted)
Density :1.252±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :≥38 mg/mL in DMSO; insoluble in H2O; ≥15.4 mg/mL in EtOH
form :powder
pka :13.54±0.46(Predicted)
color :white to beige
SMILES :O=C(NC[C@H](O)CN1CCC(C=CC=C2)=C2C1)C3=CC=NC(NC4CCC4)=C3
Density :1.252±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :≥38 mg/mL in DMSO; insoluble in H2O; ≥15.4 mg/mL in EtOH
form :powder
pka :13.54±0.46(Predicted)
color :white to beige
SMILES :O=C(NC[C@H](O)CN1CCC(C=CC=C2)=C2C1)C3=CC=NC(NC4CCC4)=C3
Safety Information
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Description
GSK591 is a chemical probe of PRMT5 (protein arginine methyltransferase 5), which plays a key role in various biological processes. PRMT5 is related to many human diseases including certain cancers like mantle cell lymphoma (MCL). Therefore, GSK591 is a useful tool for testing biological and therapeutic hypotheses. Study has shown that it can potential inhibit the PRMT5/MEP50 complex and symmetric arginine methylation of SMD3.More related product prices
1675201-83-8 N-5-benzothiazolyl-6-[(1-methylethyl)sulfonyl]-4-Quinolinamine ROR gamma-t-IN-1 GSK5959 890842-28-1 GSK6853 937174-76-0Related product price
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