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ChemicalBook >> CAS DataBase List >> HG-9-91-01

HG-9-91-01

HG-9-91-01 price.
  • $72 - $2260
  • Product name: HG-9-91-01
  • CAS: 1456858-58-4
  • MF: C32H37N7O3
  • MW: 567.68
  • EINECS:-0
  • MDL Number:MFCD28167714
  • Synonyms:HG-9-91-01;N-(2,4-Dimethoxyphenyl)-N'-(2,6-dimethylphenyl)-N-[6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]urea;1-(2,4-dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-(6-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)urea;SIK INHIBITOR 1;1-(2,4-dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-[6-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]urea;Urea, N-(2,4-dimethoxyphenyl)-N'-(2,6-dimethylphenyl)-N-[6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]-;Salt-inducible Kinase (SIK),HG99101,SIK inhibitor-1,SIK inhibitor1,inhibit,HG 9 91 01,Inhibitor;H -9-91-01
Price54 Properties Safety Information Description
54 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
Package
  • 500μg
  • 2x5mg
  • 10mM*1mLinDMSO(Solution)
  • 10mM(1mLinDMSO)
  • 250mg
  • 5 mg
  • 25 mg
  • 10mM*1mLinDMSO
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 1G
  • Manufactureraablocks
  • Product numberAA00ABHK
  • Product descriptionN-(2,4-Dimethoxyphenyl)-N'-(2,6-dimethylphenyl)-N-[6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]urea 95
  • Packaging1mg
  • Price$81
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABHK
  • Product descriptionN-(2,4-Dimethoxyphenyl)-N'-(2,6-dimethylphenyl)-N-[6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]urea 95
  • Packaging5mg
  • Price$132
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABHK
  • Product descriptionN-(2,4-Dimethoxyphenyl)-N'-(2,6-dimethylphenyl)-N-[6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]urea 95
  • Packaging10mg
  • Price$203
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABHK
  • Product descriptionN-(2,4-Dimethoxyphenyl)-N'-(2,6-dimethylphenyl)-N-[6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]urea 95
  • Packaging25mg
  • Price$384
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABHK
  • Product descriptionN-(2,4-Dimethoxyphenyl)-N'-(2,6-dimethylphenyl)-N-[6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]urea 95%
  • Packaging100mg
  • Price$1111
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY232541
  • Product descriptionHG-9-91-01 98%
  • Packaging1G
  • Price$2260
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY232541
  • Product descriptionHG-9-91-01 98%
  • Packaging100MG
  • Price$790
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY232541
  • Product descriptionHG-9-91-01 98%
  • Packaging25MG
  • Price$305
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number1537DY
  • Product descriptionCID78357808
  • Packaging1mg
  • Price$233
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1052
  • Product descriptionHG-9-91-01
  • Packaging10mg
  • Price$315
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1052
  • Product descriptionHG-9-91-01
  • Packaging5mg
  • Price$195
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1052
  • Product descriptionHG-9-91-01
  • Packaging2mg
  • Price$148
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberB1052
  • Product descriptionHG-9-91-01
  • Packaging50mg
  • Price$795
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberB1052
  • Product descriptionHG-9-91-01
  • Packaging100mg
  • Price$1237
  • Updated2026-05-06
  • Buy
  • ManufacturerArctom
  • Product numberHY-15776
  • Product descriptionHG-9-91-01 99.77%
  • Packaging100mg
  • Price$1045
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-15776
  • Product descriptionHG-9-91-01 99.77%
  • Packaging5mg
  • Price$164
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00ABHK N-(2,4-Dimethoxyphenyl)-N'-(2,6-dimethylphenyl)-N-[6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]urea 95 1mg $81 2026-05-28 Buy
aablocks AA00ABHK N-(2,4-Dimethoxyphenyl)-N'-(2,6-dimethylphenyl)-N-[6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]urea 95 5mg $132 2026-05-28 Buy
aablocks AA00ABHK N-(2,4-Dimethoxyphenyl)-N'-(2,6-dimethylphenyl)-N-[6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]urea 95 10mg $203 2026-05-28 Buy
aablocks AA00ABHK N-(2,4-Dimethoxyphenyl)-N'-(2,6-dimethylphenyl)-N-[6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]urea 95 25mg $384 2026-05-28 Buy
aablocks AA00ABHK N-(2,4-Dimethoxyphenyl)-N'-(2,6-dimethylphenyl)-N-[6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]urea 95% 100mg $1111 2026-05-28 Buy
ACHEMBLOCK Y232541 HG-9-91-01 98% 1G $2260 2026-05-27 Buy
ACHEMBLOCK Y232541 HG-9-91-01 98% 100MG $790 2026-05-27 Buy
ACHEMBLOCK Y232541 HG-9-91-01 98% 25MG $305 2026-05-27 Buy
AK Scientific 1537DY CID78357808 1mg $233 2021-12-16 Buy
ApexBio Technology B1052 HG-9-91-01 10mg $315 2026-05-06 Buy
ApexBio Technology B1052 HG-9-91-01 5mg $195 2026-05-06 Buy
ApexBio Technology B1052 HG-9-91-01 2mg $148 2026-05-06 Buy
ApexBio Technology B1052 HG-9-91-01 50mg $795 2026-05-06 Buy
ApexBio Technology B1052 HG-9-91-01 100mg $1237 2026-05-06 Buy
Arctom HY-15776 HG-9-91-01 99.77% 100mg $1045 2026-05-26 Buy
Arctom HY-15776 HG-9-91-01 99.77% 5mg $164 2026-05-26 Buy
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Properties

Boiling point :790.8±60.0 °C(Predicted)
Density :1.257±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥56.8 mg/mL in DMSO; ≥27.3 mg/mL in EtOH; ≥6.35 mg/mL in H2O with ultrasonic
form :Powder
pka :13.11±0.70(Predicted)
color :White to yellow

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

HG-9-91-01 is an inhibitor of salt-inducible kinases (SIKs; IC50s = 0.92, 6.6, and 9.6 nM for SIK1, SIK2, and SIK3, respectively). It also inhibits Src, Lck, Yes, and BTK, as well as FGF and Ephrin receptors. HG-9-91-01 increases LPS-stimulated IL-10 production and suppresses pro-inflammatory cytokine secretion in bone marrow-derived macrophages. SIK inhibitors, including HG-9-91-01, enhance CREB-dependent gene transcription and IL-10 production in bone marrow-derived dendritic cells, THP-1 cells, and human primary macrophages.

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Suppliers and manufacturers

Shanghai Boyle Chemical Co., Ltd. Haoyuan Chemexpress Co., Ltd. MedChemexpress LLC LETOPHARM LIMITED Shanghai Lollane Biological Technology Co.,Ltd. Shanghaizehan biopharma technology co., Ltd. SPIRO PHARMA Shanghai EFE Biological Technology Co., Ltd. Guangzhou QiYun Biotechnology Co., Ltd. Shanghai YuanYe Biotechnology Co., Ltd.