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ChemicalBook >> CAS DataBase List >> HMN-214

HMN-214

HMN-214 price.
  • $5 - $2200
  • Product name: HMN-214
  • CAS: 173529-46-9
  • MF: C22H20N2O5S
  • MW: 424.47
  • EINECS:
  • MDL Number:MFCD12756255
  • Synonyms:HMN-214;(E)-4-[2-[2-[N-Acetyl-N-[(4-methoxyphenyl)sulfonyl]amino]phenyl]ethenyl]pyridine 1-oxide;HMN-214;HMN214;HMN 214;Acetamide, N-[(4-methoxyphenyl)sulfonyl]-N-[2-[(1E)-2-(1-oxido-4-pyridinyl)ethenyl]phenyl]-;(E)-4-[2-[2-[N-Acetyl-N-[(4-methoxyphenyl)sulfonyl]amino]phenyl]ethenyl]pyridine 1-oxide HMN 214;(E)-4-(2-(N-((4-methoxyphenyl)sulfonyl)acetamido)styryl)pyridine 1-oxide;HMN-214;HMN214;HMN 214;IVX214;CS-25
Price38 Properties Safety Information Description
38 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • TRC
Package
  • 10mM(in 1mL DMSO)
  • 5.00mg
  • 1mg
  • 10mM(in1mLDMSO)
  • 5mg
  • 10mg
  • 10.00mg
  • 25mg
  • 25.00mg
  • 50mg
  • 100mg
  • 250MG
  • 1G
  • Manufactureraablocks
  • Product numberAA001YXD
  • Product descriptionHMN-214 98%
  • Packaging1mg
  • Price$19
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001YXD
  • Product descriptionHMN-214 98%
  • Packaging5mg
  • Price$48
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001YXD
  • Product descriptionHMN-214 98%
  • Packaging10mg
  • Price$72
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001YXD
  • Product descriptionHMN-214 98%
  • Packaging25mg
  • Price$108
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001YXD
  • Product descriptionHMN-214 98%
  • Packaging50mg
  • Price$165
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001YXD
  • Product descriptionHMN-214 98%
  • Packaging100mg
  • Price$249
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65796
  • Product description(E)-4-(2-(N-((4-methoxyphenyl)sulfonyl)acetamido)styryl)pyridine 1-oxide 98%
  • Packaging250MG
  • Price$325
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65796
  • Product description(E)-4-(2-(N-((4-methoxyphenyl)sulfonyl)acetamido)styryl)pyridine 1-oxide 98%
  • Packaging1G
  • Price$680
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65796
  • Product description(E)-4-(2-(N-((4-methoxyphenyl)sulfonyl)acetamido)styryl)pyridine 1-oxide 98%
  • Packaging100MG
  • Price$215
  • Updated2026-05-27
  • Buy
  • ManufacturerAmbeed
  • Product numberA136004
  • Product descriptionHMN-214 98+%
  • Packaging25mg
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0005218
  • Product descriptionHMN-214 95.00%
  • Packaging5MG
  • Price$330
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5413
  • Product descriptionHMN-214
  • Packaging10mg
  • Price$156
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5413
  • Product descriptionHMN-214
  • Packaging50mg
  • Price$552
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5413
  • Product descriptionHMN-214
  • Packaging10mM(in 1mL DMSO)
  • Price$176
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5413
  • Product descriptionHMN-214
  • Packaging10mM(in1mLDMSO)
  • Price$116
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5413
  • Product descriptionHMN-214
  • Packaging5mg
  • Price$95
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA001YXD HMN-214 98% 1mg $19 2026-05-28 Buy
aablocks AA001YXD HMN-214 98% 5mg $48 2026-05-28 Buy
aablocks AA001YXD HMN-214 98% 10mg $72 2026-05-28 Buy
aablocks AA001YXD HMN-214 98% 25mg $108 2026-05-28 Buy
aablocks AA001YXD HMN-214 98% 50mg $165 2026-05-28 Buy
aablocks AA001YXD HMN-214 98% 100mg $249 2026-05-28 Buy
ACHEMBLOCK Q65796 (E)-4-(2-(N-((4-methoxyphenyl)sulfonyl)acetamido)styryl)pyridine 1-oxide 98% 250MG $325 2026-05-27 Buy
ACHEMBLOCK Q65796 (E)-4-(2-(N-((4-methoxyphenyl)sulfonyl)acetamido)styryl)pyridine 1-oxide 98% 1G $680 2026-05-27 Buy
ACHEMBLOCK Q65796 (E)-4-(2-(N-((4-methoxyphenyl)sulfonyl)acetamido)styryl)pyridine 1-oxide 98% 100MG $215 2026-05-27 Buy
Ambeed A136004 HMN-214 98+% 25mg $99 2021-12-16 Buy
American Custom Chemicals Corporation API0005218 HMN-214 95.00% 5MG $330 2021-12-16 Buy
ApexBio Technology A5413 HMN-214 10mg $156 2026-05-06 Buy
ApexBio Technology A5413 HMN-214 50mg $552 2026-05-06 Buy
ApexBio Technology A5413 HMN-214 10mM(in 1mL DMSO) $176 2021-12-16 Buy
ApexBio Technology A5413 HMN-214 10mM(in1mLDMSO) $116 2026-05-06 Buy
ApexBio Technology A5413 HMN-214 5mg $95 2026-05-06 Buy
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Properties

Boiling point :663.1±65.0 °C(Predicted)
Density :1.24
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :≥21.2 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :solid
pka :0.86±0.10(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

HMN-214 is an orally bioavailable prodrug form of HMN-176, an indirect inhibitor of polo-like kinase (PLK) activity that inhibits proliferation of a variety of cancer cells. HMN-214 decreases the expression of multidrug resistance gene 1 (MDR1) in AB-A.1 cells and in tumors isolated from mice bearing multidrug-resistant KB-A1 xenografts. HMN-214 (20 mg/kg per day) reduces tumor volume in PC3, WiDr, and A549 mouse xenograft models. It does not decrease nerve conduction velocity or compound action potential amplitude in rabbit sciatic nerves in vivo when administered at a concentration of 30 mg/kg per day.

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Suppliers and manufacturers

Shanghai Boyle Chemical Co., Ltd. Chembest Research Laboratories Limited JinYan Chemicals(ShangHai) Co.,Ltd. Shanghai Hanhong Scientific Co.,Ltd. Jinan Trio PharmaTech Co., Ltd. Dalian Meilun Biotech Co., Ltd. Shanghai civi chemical technology co.,Ltd NCE Biomedical Co.,Ltd. Haoyuan Chemexpress Co., Ltd. Shanghai Aladdin Bio-Chem Technology Co.,LTD