IKE
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- $72 - $2822
- Product name: IKE
- CAS: 1801530-11-9
- MF: C35H35ClN6O5
- MW: 655.14
- EINECS:
- MDL Number:
- Synonyms:IKE);Imidazole ketone erastin (Ferroptosis inducer IKE;Ferroptosis inducer IKE;IMIDAZOLE KETONE ERASTIN;FERROPTOSIS INDUCER IKE;IKE;4(3H)-Quinazolinone, 2-[[4-[2-(4-chlorophenoxy)acetyl]-1-piperazinyl]methyl]-3-[5-[2-(1H-imidazol-1-yl)acetyl]-2-(1-methylethoxy)phenyl]-;3-(5-(2-(1H-Imidazol-1-yl)acetyl)-2-isopropoxyphenyl)-2-((4-(2-(4-chlorophenoxy)acetyl)piperazin-1-yl)methyl)quinazolin-4(3H)-one;PUN-30119;Imidazole ketone erastin (PUN30119)
35 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- ApexBio Technology
- Arctom
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
Package
- 10mM*1mLinDMSO
- 1mg
- 10mM(1mLinDMSO)
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250MG
- 1g
- Manufactureraablocks
- Product numberAA01KKYT
- Product descriptionIKE 99
- Packaging1mg
- Price$72
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01KKYT
- Product descriptionIKE 99
- Packaging2mg
- Price$91
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01KKYT
- Product descriptionIKE 99%
- Packaging10mg
- Price$162
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01KKYT
- Product descriptionIKE 99%
- Packaging5mg
- Price$122
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01KKYT
- Product descriptionIKE 99
- Packaging25mg
- Price$303
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01KKYT
- Product descriptionIKE 99%
- Packaging50mg
- Price$418
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01KKYT
- Product descriptionIKE 99
- Packaging100mg
- Price$589
- Updated2026-05-30
- Buy
- ManufacturerACHEMBLOCK
- Product numberX203238
- Product descriptionIKE 98.00%
- Packaging100MG
- Price$850
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX203238
- Product descriptionIKE 98.00%
- Packaging250MG
- Price$1700
- Updated2026-05-27
- Buy
- ManufacturerApexBio Technology
- Product numberC8432
- Product descriptionImidazole ketone erastin
- Packaging5mg
- Price$145
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC8432
- Product descriptionImidazole ketone erastin
- Packaging10mg
- Price$230
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberSLK-S8877
- Product descriptionImidazole ketone erastin (PUN30119) 99.51%
- Packaging5mg
- Price$245
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberSLK-S8877
- Product descriptionImidazole ketone erastin (PUN30119) 99.51%
- Packaging10mM(1mLinDMSO)
- Price$283
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberSLK-S8877
- Product descriptionImidazole ketone erastin (PUN30119) 99.51%
- Packaging2mg
- Price$169
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberSLK-S8877
- Product descriptionImidazole ketone erastin (PUN30119) 99.51%
- Packaging100mg
- Price$1207
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberSLK-S8877
- Product descriptionImidazole ketone erastin (PUN30119) 99.51%
- Packaging25mg
- Price$732
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01KKYT | IKE 99 | 1mg | $72 | 2026-05-30 | Buy |
| aablocks | AA01KKYT | IKE 99 | 2mg | $91 | 2026-05-30 | Buy |
| aablocks | AA01KKYT | IKE 99% | 10mg | $162 | 2026-05-30 | Buy |
| aablocks | AA01KKYT | IKE 99% | 5mg | $122 | 2026-05-30 | Buy |
| aablocks | AA01KKYT | IKE 99 | 25mg | $303 | 2026-05-30 | Buy |
| aablocks | AA01KKYT | IKE 99% | 50mg | $418 | 2026-05-30 | Buy |
| aablocks | AA01KKYT | IKE 99 | 100mg | $589 | 2026-05-30 | Buy |
| ACHEMBLOCK | X203238 | IKE 98.00% | 100MG | $850 | 2026-05-27 | Buy |
| ACHEMBLOCK | X203238 | IKE 98.00% | 250MG | $1700 | 2026-05-27 | Buy |
| ApexBio Technology | C8432 | Imidazole ketone erastin | 5mg | $145 | 2026-05-06 | Buy |
| ApexBio Technology | C8432 | Imidazole ketone erastin | 10mg | $230 | 2026-05-06 | Buy |
| Arctom | SLK-S8877 | Imidazole ketone erastin (PUN30119) 99.51% | 5mg | $245 | 2026-05-26 | Buy |
| Arctom | SLK-S8877 | Imidazole ketone erastin (PUN30119) 99.51% | 10mM(1mLinDMSO) | $283 | 2026-05-26 | Buy |
| Arctom | SLK-S8877 | Imidazole ketone erastin (PUN30119) 99.51% | 2mg | $169 | 2026-05-26 | Buy |
| Arctom | SLK-S8877 | Imidazole ketone erastin (PUN30119) 99.51% | 100mg | $1207 | 2026-05-26 | Buy |
| Arctom | SLK-S8877 | Imidazole ketone erastin (PUN30119) 99.51% | 25mg | $732 | 2026-05-26 | Buy |
Properties
Boiling point :886.5±75.0 °C(Predicted)
Density :1.34±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMF: 10mg/mL,DMSO: 1mg/mL,DMSO:PBS (pH 7.2) (1:2): 0.25mg/mL
form :A crystalline solid
pka :6.12±0.10(Predicted)
color :White to yellow
InChIKey :PSPXJPWGVFNGQI-UHFFFAOYSA-N
SMILES :N1C2=C(C=CC=C2)C(=O)N(C2=CC(C(CN3C=NC=C3)=O)=CC=C2OC(C)C)C=1CN1CCN(C(COC2=CC=C(Cl)C=C2)=O)CC1
Density :1.34±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMF: 10mg/mL,DMSO: 1mg/mL,DMSO:PBS (pH 7.2) (1:2): 0.25mg/mL
form :A crystalline solid
pka :6.12±0.10(Predicted)
color :White to yellow
InChIKey :PSPXJPWGVFNGQI-UHFFFAOYSA-N
SMILES :N1C2=C(C=CC=C2)C(=O)N(C2=CC(C(CN3C=NC=C3)=O)=CC=C2OC(C)C)C=1CN1CCN(C(COC2=CC=C(Cl)C=C2)=O)CC1
Safety Information
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Description
Imidazole ketone erastin is an inducer of ferroptosis. It inhibits glutamate release in human CCF-STTG1 astrocytoma cells (IC50 = 30 nM), indicating inhibition of the system xc- cystine/glutamate transporter. Imidazole ketone erastin increases production of lipid reactive oxygen species (ROS) in SUDHL6 diffuse large B cell lymphoma (DLBCL) cells in a concentration-dependent manner, as well as reduces glutathione (GSH) levels in these cells (IC50 = 34 nM). It inhibits the growth of HT-1080 fibrosarcoma cells (GI50 = 310 nM) as well as HRASG12V-overexpressing BJeLR cells (IC50 = 3 nM). Imidazole ketone erastin (23 and 40 mg/kg) reduces tumor growth in an SUDHL6 mouse xenograft model.More related product prices
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