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ChemicalBook >> CAS DataBase List >> Irbesartan

Irbesartan

Irbesartan price.
  • $5 - $1200
  • Product name: Irbesartan
  • CAS: 138402-11-6
  • MF: C25H28N6O
  • MW: 428.53
  • EINECS:604-078-2
  • MDL Number:MFCD00864464
  • Synonyms:2-BUTYL-3-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,3-DIAZASPIRO[4.4]NON-1-EN-4-ONE;IRBESARTAN;BMS-186295;APROVEL;1,3-Diazaspiro[4.4]non-1-en-4-one, 2-butyl-3-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-;2-Isopropryl-4-methylthiazole;2-butyl-3-[[4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one;2-butyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one
97 prices
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Brand
  • Adipogen Life Sciences
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AstaTech
  • AvaChem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • Chem-Impex
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Thermo Scientific Chemicals
  • Tocris
  • TRC
  • Usbiological
Package
  • 10mM*1mLinDMSO
  • 10mg
  • y0001166
  • 200mg
  • 500mg
  • 50G
  • 1000g
  • 5 g
  • 10/ G
  • 50
  • 50/ G
  • 60 mg
  • 250/ G
  • 10mM*1mLinDMSO(Solution)
  • 5mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 5g
  • 10g
  • 10mM(in1mLDMSO)
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 25g
  • 100g
  • 500g
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-I0204-M050
  • Product descriptionIrbesartan ≥98%(HPLC)
  • Packaging50mg
  • Price$105
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-I0204-M250
  • Product descriptionIrbesartan ≥98%(HPLC)
  • Packaging250mg
  • Price$421
  • Updated2026-05-06
  • Buy
  • ManufacturerAmbeed
  • Product numberA262974
  • Product descriptionIrbesartan 95%
  • Packaging500g
  • Price$354
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA262974
  • Product descriptionIrbesartan 95%
  • Packaging100g
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA262974
  • Product descriptionIrbesartan 95%
  • Packaging25g
  • Price$42
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA262974
  • Product descriptionIrbesartan 95%
  • Packaging10g
  • Price$19
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA262974
  • Product descriptionIrbesartan 95%
  • Packaging5g
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA262974
  • Product descriptionIrbesartan 95%
  • Packaging1g
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA262974
  • Product descriptionIrbesartan 95%
  • Packaging250mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003025
  • Product descriptionIRBESARTAN 95.00%
  • Packaging1G
  • Price$130.2
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5970
  • Product descriptionIrbesartan
  • Packaging100mg
  • Price$227
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5970
  • Product descriptionIrbesartan
  • Packaging25mg
  • Price$77
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5970
  • Product descriptionIrbesartan
  • Packaging25mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5970
  • Product descriptionIrbesartan
  • Packaging5mg
  • Price$50
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5970
  • Product descriptionIrbesartan
  • Packaging10mM(in1mLDMSO)
  • Price$61
  • Updated2026-05-06
  • Buy
  • ManufacturerArctom
  • Product numberAS498571
  • Product descriptionIrbesartan 95%
  • Packaging1g
  • Price$6
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-I0204-M050 Irbesartan ≥98%(HPLC) 50mg $105 2026-05-06 Buy
Adipogen Life Sciences CDX-I0204-M250 Irbesartan ≥98%(HPLC) 250mg $421 2026-05-06 Buy
Ambeed A262974 Irbesartan 95% 500g $354 2021-12-16 Buy
Ambeed A262974 Irbesartan 95% 100g $115 2021-12-16 Buy
Ambeed A262974 Irbesartan 95% 25g $42 2021-12-16 Buy
Ambeed A262974 Irbesartan 95% 10g $19 2021-12-16 Buy
Ambeed A262974 Irbesartan 95% 5g $11 2021-12-16 Buy
Ambeed A262974 Irbesartan 95% 1g $6 2021-12-16 Buy
Ambeed A262974 Irbesartan 95% 250mg $5 2021-12-16 Buy
American Custom Chemicals Corporation API0003025 IRBESARTAN 95.00% 1G $130.2 2021-12-16 Buy
ApexBio Technology A5970 Irbesartan 100mg $227 2026-05-06 Buy
ApexBio Technology A5970 Irbesartan 25mg $77 2026-05-06 Buy
ApexBio Technology A5970 Irbesartan 25mg $80 2021-12-16 Buy
ApexBio Technology A5970 Irbesartan 5mg $50 2026-05-06 Buy
ApexBio Technology A5970 Irbesartan 10mM(in1mLDMSO) $61 2026-05-06 Buy
Arctom AS498571 Irbesartan 95% 1g $6 2021-12-16 Buy

Properties

Melting point :180-181°C
Boiling point :648.6±65.0 °C(Predicted)
Density :1.30±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >25mg/mL
pka :4.16±0.10(Predicted)
form :powder
color :white to off-white
Merck :14,5083
BCS Class :2
InChIKey :YOSHYTLCDANDAN-UHFFFAOYSA-N
SMILES :N1C2(CCCC2)C(=O)N(CC2=CC=C(C3=CC=CC=C3C3=NNN=N3)C=C2)C=1CCCC
CAS DataBase Reference :138402-11-6(CAS DataBase Reference)
EPA Substance Registry System :1,3-Diazaspiro[4.4]non-1-en-4-one, 2-butyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- (138402-11-6)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P273 Avoid release to the environment.
P501 Dispose of contents/container to..…

Description

Angiotensin II receptor blockers (ARBs) act as cardioprotective agents that are effective in hypertension, left ventricular hypertrophy, postmyocardial infarction, and heart failure. Irbesartan is an ARB with a high affinity for the AT1 receptor (Ki = 2.7 nM) and exceptionally high bioavailability (60-80%). It is an insurmountable antagonist of AT1, as its antagonism of this receptor cannot be overcome by increasing concentrations of angiotensin II. Irbesartan effectively reduces blood pressure alone but may also be used in combination with a diuretic, such as hydrochlorothiazide. As angiotensin II contributes in diverse ways to endothelial dysfunction, irbesartan and other ARBs directly protect the vascular endothelium. Other pathologies, including diabetes and kidney disease, also benefit from the cardiovascular and endothelial protective actions of ARBs like irbesartan.

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