JERVINE
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- $32 - $1800
- Product name: JERVINE
- CAS: 469-59-0
- MF: C27H39NO3
- MW: 425.6
- EINECS:207-417-9
- MDL Number:MFCD01684066
- Synonyms:Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetraMethyl-,(2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-;17,23-epoxy-3-hydroxy-,(3-beta,23-beta)-veratraman-11-on ;17,23-epoxy-3-hydroxy-,(3beta,23beta)-veratraman-11-on ;4’,5’,6,6’,6a,6b,7,7’,7’a,8,11a,11b-hexadecahydro-3-hydroxy-3’,6’,10,11b-tetra ;Iervin;(2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one;jerwiny ;Spiro(9H-benzo(a)fluorene-9,2'(3'H)-furo(3,2-b)-pyridin)-11(1H)-one,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-
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Brand
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
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Package
- 1mg
- 5mg
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- 50mg
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- 100MG
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- 500mg
- 1000mg
- 1g
- ManufacturerACHEMBLOCK
- Product numberV143149
- Product descriptionJervine 98%
- Packaging100MG
- Price$900
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberV143149
- Product descriptionJervine 98%
- Packaging25MG
- Price$325
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberV143149
- Product descriptionJervine 98%
- Packaging250MG
- Price$1800
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberX0086
- Product descriptionJervine
- Packaging50mg
- Price$410
- Updated2021-12-16
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- ManufacturerAK Scientific
- Product numberX0086
- Product descriptionJervine
- Packaging5mg
- Price$158
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8656
- Product descriptionJervine
- Packaging5mg
- Price$109
- Updated2026-05-06
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- ManufacturerApexBio Technology
- Product numberA8656
- Product descriptionJervine
- Packaging10mg
- Price$203
- Updated2026-05-06
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- ManufacturerApexBio Technology
- Product numberA8656
- Product descriptionJervine
- Packaging50mg
- Price$880
- Updated2026-05-06
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- ManufacturerApexBio Technology
- Product numberA8656
- Product descriptionJervine
- Packaging50mg
- Price$1319
- Updated2021-12-16
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- ManufacturerArctom
- Product numberHY-N0836R
- Product descriptionJervine (Standard)
- Packaging50mg
- Price$1236
- Updated2026-05-25
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- ManufacturerArctom
- Product numberHY-N0836R
- Product descriptionJervine (Standard)
- Packaging50mg
- Price$1236
- Updated2026-05-26
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- ManufacturerArctom
- Product numberHY-N0836R
- Product descriptionJervine (Standard)
- Packaging25mg
- Price$883
- Updated2026-05-25
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- ManufacturerArctom
- Product numberHY-N0836R
- Product descriptionJervine (Standard)
- Packaging25mg
- Price$883
- Updated2026-05-26
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- ManufacturerArctom
- Product numberHY-N0836
- Product descriptionJervine 99.28%
- Packaging100mg
- Price$867
- Updated2026-05-25
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- ManufacturerArctom
- Product numberHY-N0836
- Product descriptionJervine 99.28%
- Packaging100mg
- Price$867
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-N0836
- Product descriptionJervine 99.28%
- Packaging50mg
- Price$618
- Updated2026-05-25
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | V143149 | Jervine 98% | 100MG | $900 | 2026-05-27 | Buy |
| ACHEMBLOCK | V143149 | Jervine 98% | 25MG | $325 | 2026-05-27 | Buy |
| ACHEMBLOCK | V143149 | Jervine 98% | 250MG | $1800 | 2026-05-27 | Buy |
| AK Scientific | X0086 | Jervine | 50mg | $410 | 2021-12-16 | Buy |
| AK Scientific | X0086 | Jervine | 5mg | $158 | 2021-12-16 | Buy |
| ApexBio Technology | A8656 | Jervine | 5mg | $109 | 2026-05-06 | Buy |
| ApexBio Technology | A8656 | Jervine | 10mg | $203 | 2026-05-06 | Buy |
| ApexBio Technology | A8656 | Jervine | 50mg | $880 | 2026-05-06 | Buy |
| ApexBio Technology | A8656 | Jervine | 50mg | $1319 | 2021-12-16 | Buy |
| Arctom | HY-N0836R | Jervine (Standard) | 50mg | $1236 | 2026-05-25 | Buy |
| Arctom | HY-N0836R | Jervine (Standard) | 50mg | $1236 | 2026-05-26 | Buy |
| Arctom | HY-N0836R | Jervine (Standard) | 25mg | $883 | 2026-05-25 | Buy |
| Arctom | HY-N0836R | Jervine (Standard) | 25mg | $883 | 2026-05-26 | Buy |
| Arctom | HY-N0836 | Jervine 99.28% | 100mg | $867 | 2026-05-25 | Buy |
| Arctom | HY-N0836 | Jervine 99.28% | 100mg | $867 | 2026-05-26 | Buy |
| Arctom | HY-N0836 | Jervine 99.28% | 50mg | $618 | 2026-05-25 | Buy |
Properties
Melting point :242- 244°C
alpha :D20 -150° (ethanol) (Saito); D20 -167.6° (chloroform) (Poethke)
Boiling point :541.31°C (rough estimate)
Density :1.18±0.1 g/cm3 (20 ºC 760 Torr)
refractive index :1.6400 (estimate)
storage temp. :−20°C
solubility :methanol: >2 mg/mL
form :solid
pka :14.98±0.70(Predicted)
color :White
λmax :250nm(lit.)
Merck :14,5264
Stability :Store in Freezer at - 20°C
InChIKey :CLEXYFLHGFJONT-DNMILWOZSA-N
SMILES :[H][C@@]12C[C@H](C)CN[C@@]1([H])[C@@H](C)[C@@]3(CC[C@]4([H])C(=C3C)C(=O)[C@@]5([H])[C@@]4([H])CC=C6C[C@@H](O)CC[C@]56C)O2
alpha :D20 -150° (ethanol) (Saito); D20 -167.6° (chloroform) (Poethke)
Boiling point :541.31°C (rough estimate)
Density :1.18±0.1 g/cm3 (20 ºC 760 Torr)
refractive index :1.6400 (estimate)
storage temp. :−20°C
solubility :methanol: >2 mg/mL
form :solid
pka :14.98±0.70(Predicted)
color :White
λmax :250nm(lit.)
Merck :14,5264
Stability :Store in Freezer at - 20°C
InChIKey :CLEXYFLHGFJONT-DNMILWOZSA-N
SMILES :[H][C@@]12C[C@H](C)CN[C@@]1([H])[C@@H](C)[C@@]3(CC[C@]4([H])C(=C3C)C(=O)[C@@]5([H])[C@@]4([H])CC=C6C[C@@H](O)CC[C@]56C)O2
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | ||||||||||||||
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Description
Jervine is a naturally occuring steroidal alkaloid that causes cyclopia by blocking sonic hedgehog signaling. This is derived from the Veratrum plant species. It is a close structural analog of cyclopamine which specifically inhibits the hedgehog (Hh) pathway by interaction with the hedgehog signaling protein Smo. Jervine can be used to induce abnormal morphogenesis in a number of experimental models. Jervine is an inhibitor of Smo.More related product prices
329196-48-7 LDE-225 Diphosphate Smoothened Agonist, HCl PROTOVERATRINE A VERATRIDINE veratramine 35158-25-9 DL-IsoleucineRelated product price
- 329196-48-7
$35-1253 - LDE-225 Diphosphate
$32-1802 - Smoothened Agonist, HCl
$30-1140
Suppliers and manufacturers
Shanghai Zheyan Biotech Co., Ltd.
Chengdu GLP biotechnology Co Ltd
Chengdu Biopurify Phytochemicals Ltd.
BOC Sciences
Neostar United (Changzhou) Industrial Co., Ltd.
Wuhan ChemNorm Biotech Co.,Ltd.
